Ferroptosis

Corrigendum to "The mechanism of hypoxia-inducible factor-1α enhancing the transcriptional activity of transferrin ferroportin 1 and regulating the Nrf2/HO-1 pathway in ferroptosis after cerebral ischemic injury". [Neuroscience 559 (2024) 26-38].

Neuroscience

Abstract

Key Findings

  • Hypoxia-inducible factor-1α enhances the transcriptional activity of transferrin and ferroportin 1.
  • HIF-1α regulates the Nrf2/HO-1 pathway during ferroptosis after cerebral ischemic injury.
  • The interplay between HIF-1α and Nrf2/HO-1 pathway influences ferroptosis mechanisms in brain injury.

Clinical Significance

Understanding the regulation of ferroptosis via HIF-1α and Nrf2/HO-1 pathways offers potential therapeutic targets for reducing neuronal damage after cerebral ischemic injury.

Citation

Yao Haiqian, Tian Jianan, Cheng Shiet al.. Corrigendum to "The mechanism of hypoxia-inducible factor-1α enhancing the transcriptional activity of transferrin ferroportin 1 and regulating the Nrf2/HO-1 pathway in ferroptosis after cerebral ischemic injury". [Neuroscience 559 (2024) 26-38]. Neuroscience. 2026-Apr-06.

DOI: 10.1016/j.neuroscience.2026.01.018