Which NRF2 Products Have Peer Reviewed Studies

English: Graph of Nrf2 publications (pubmed search) by year (Photo credit: Wikipedia)

There are currently over 2300 articles (peer reviewed clinical reviews and studies) on Pubmed.gov on the topic of NRF2 Activation. There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to Pubmed.gov and type in the name of their product. Pubmed is a website operated by the National Institute of Health (NIH). PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources. Last 200 NRF-2 Studies published on Pubmed

Li J, Xiong C, Xu P, Luo Q and Zhang R. Puerarin induces apoptosis in prostate cancer cells via inactivation of the Keap1/Nrf2/ARE signaling pathway. (2021) Bioengineered. 12, 402-413 Pubmed Bioengineered

Yasuda T, Ishimoto T and Baba H. Conflicting metabolic alterations in cancer stem cells and regulation by the stromal niche. (2021) Regen Ther. 17, 8-12 Pubmed Regen Ther PMC Article

Sahu R, Kar RK, Sunita P, Bose P, Kumari P, Bharti S, Srivastava S and Pattanayak SP. LC-MS characterized methanolic extract of zanthoxylum armatum possess anti-breast cancer activity through Nrf2-Keap1 pathway: An in-silico, in-vitro and in-vivo evaluation. (2021) J Ethnopharmacol. 269, 113758 Pubmed J Ethnopharmacol

Zhang J, Jiang D, Lin S, Cheng Y, Pan J, Ding W, Chen Y and Fan J. Prolyl endopeptidase disruption reduces hepatic inflammation and oxidative stress in methionine-choline-deficient diet-induced steatohepatitis. (2021) Life Sci. 270, 119131 Pubmed Life Sci

Dobani S, Latimer C, McDougall GJ, Allwood JW, Pereira-Caro G, Moreno-Rojas JM, Ternan NG, Pourshahidi LK, Lawther R, Tuohy KM, Del Rio D, O'Connor G, Rowland I, Almutairi TM, Crozier A and Gill CIR. Ex vivo fecal fermentation of human ileal fluid collected after raspberry consumption modifies (poly)phenolics and modulates genoprotective effects in colonic epithelial cells. (2021) Redox Biol. 40, 101862 Pubmed Redox Biol PMC Article

Kim SJ, Saeidi S, Cho NC, Kim SH, Lee HB, Han W, Noh DY and Surh YJ. Interaction of Nrf2 with dimeric STAT3 induces IL-23 expression: Implications for breast cancer progression. (2021) Cancer Lett. 500, 147-160 Pubmed Cancer Lett

Weng B, Zhang X, Chu X, Gong X and Cai C. Nrf2‑Keap1‑ARE‑NQO1 signaling attenuates hyperoxia‑induced lung cell injury by inhibiting apoptosis. (2021) Mol Med Rep. 23, 1 Pubmed Mol Med Rep

Albazal A, Delshad AA and Roghani M. Melatonin reverses cognitive deficits in streptozotocin-induced type 1 diabetes in the rat through attenuation of oxidative stress and inflammation. (2021) J Chem Neuroanat. 112, 101902 Pubmed J Chem Neuroanat

Xie J, Lai Z, Zheng X, Liao H, Xian Y, Li Q, Wu J, Ip S, Xie Y, Chen J, Su Z, Lin Z and Yang X. Apoptotic activities of brusatol in human non-small cell lung cancer cells: Involvement of ROS-mediated mitochondrial-dependent pathway and inhibition of Nrf2-mediated antioxidant response. (2021) Toxicology. 451, 152680 Pubmed Toxicology

Yao X, Sun K, Yu S, Luo J, Guo J, Lin J, Wang G, Guo Z, Ye Y and Guo F. Chondrocyte ferroptosis contribute to the progression of osteoarthritis. (2021) J Orthop Translat. 27, 33-43 Pubmed J Orthop Translat PMC Article

Kim CW, Oh ET and Park HJ. A strategy to prevent atherosclerosis via TNF receptor regulation. (2021) FASEB J. 35, e21391 Pubmed FASEB J

Mohs A, Otto T, Schneider KM, Peltzer M, Boekschoten M, Holland CH, Hudert CA, Kalveram L, Wiegand S, Saez-Rodriguez J, Longerich T, Hengstler JG and Trautwein C. Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis. (2021) J Hepatol. 74, 638-648 Pubmed J Hepatol

de Souza ICC, Gobbo RCB, de Almeida FJS, Luckachaki MD and de Oliveira MR. Carnosic acid depends on glutathione to promote mitochondrial protection in methylglyoxal-exposed SH-SY5Y cells. (2021) Metab Brain Dis. 36, 471-481 Pubmed Metab Brain Dis

Zhao B, Li GP, Peng JJ, Ren LH, Lei LC, Ye HM, Wang ZY and Zhao S. Schizandrin B attenuates hypoxia/reoxygenation injury in H9c2 cells by activating the AMPK/Nrf2 signaling pathway. (2021) Exp Ther Med. 21, 220 Pubmed Exp Ther Med PMC Article

Rui Q, Cao S, Wang X, Duan X, Iao X, Dong W, Fang Q, Zhang X and Xue Q. LMTK2 regulates inflammation in lipopolysaccharide-stimulated BV2 cells. (2021) Exp Ther Med. 21, 219 Pubmed Exp Ther Med PMC Article

Ishida K, Kaji K, Sato S, Ogawa H, Takagi H, Takaya H, Kawaratani H, Moriya K, Namisaki T, Akahane T and Yoshiji H. Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway. (2021) J Nutr Biochem. 89, 108573 Pubmed J Nutr Biochem

Sanghvi VR, Mohan P, Singh K, Cao L, Berishaj M, Wolfe AL, Schatz JH, Lailler N, de Stanchina E, Viale A and Wendel HG. NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy. (2021) Cancers (Basel). 13, Pubmed Cancers (Basel)

Zhang Z, Peng L, Fu Y, Wang W, Wang P and Zhou F. Ginnalin A Binds to the Subpockets of Keap1 Kelch Domain To Activate the Nrf2-Regulated Antioxidant Defense System in SH-SY5Y Cells. (2021) ACS Chem Neurosci. Pubmed ACS Chem Neurosci

Korac B, Kalezic A, Pekovic-Vaughan V, Korac A and Jankovic A. Redox changes in obesity, metabolic syndrome, and diabetes. (2021) Redox Biol. 101887 Pubmed Redox Biol

Zhang H, Wang S, Liu Q, Zheng H, Liu X, Wang X, Shen T and Ren D. Dracomolphin A-E, new lignans from Dracocephalum moldavica. (2021) Fitoterapia. 150, 104841 Pubmed Fitoterapia

Kozieł MJ, Kowalska K and Piastowska-Ciesielska AW. Nrf2: a main responsive element in cells to mycotoxin-induced toxicity. (2021) Arch Toxicol. Pubmed Arch Toxicol

Teng RJ, Jing X, Martin DP, Hogg N, Haefke A, Konduri GG, Day BW, Naylor S and Pritchard KA. N-Acetyl-Lysyltyrosylcysteine Amide, a Novel Systems Pharmacology Agent, Reduces Bronchopulmonary Dysplasia in Hyperoxic Neonatal Rat Pups. (2021) Free Radic Biol Med. Pubmed Free Radic Biol Med

Yu ZM, Wan XM, Xiao M, Zheng C and Zhou XL. Puerarin induces Nrf2 as a cytoprotective mechanism to prevent cadmium-induced autophagy inhibition and NLRP3 inflammasome activation in AML12 hepatic cells. (2021) J Inorg Biochem. 217, 111389 Pubmed J Inorg Biochem

El-Sayed RM, Abo El Gheit RE and Badawi GA. Vincamine protects against cisplatin induced nephrotoxicity via activation of Nrf2/HO-1 and hindering TLR4/ IFN-γ/CD44 cells inflammatory cascade. (2021) Life Sci. 272, 119224 Pubmed Life Sci

El-Akad RH, Abou Zeid AH, El-Rafie HM, Kandil ZA and Farag MA. Comparative metabolites profiling of Caryota mitis & Caryota urens via UPLC/MS and isolation of two novel in silico chemopreventive flavonoids. (2021) J Food Biochem. e13648 Pubmed J Food Biochem

Wang W, Li S and Song M. polysaccharide inhibits high glucose-induced oxidative stress, inflammatory response, and apoptosis in RPE cells. (2021) J Recept Signal Transduct Res. 1-8 Pubmed J Recept Signal Transduct Res

Rizvi A, Farhan M, Nabi F, Khan RH, Adil M and Ahmad A. Transcriptional control of the oxidative stress response and implications of using plant derived molecules for therapeutic interventions in cancer. (2021) Curr Med Chem. Pubmed Curr Med Chem

Sayed EA, Badr G, Hassan KA, Waly H, Ozdemir B, Mahmoud MH and Alamery S. Induction of liver fibrosis by CCl4 mediates pathological alterations in the spleen and lymph nodes: The potential therapeutic role of propolis. (2021) Saudi J Biol Sci. 28, 1272-1282 Pubmed Saudi J Biol Sci PMC Article

Fu C, Zheng Y, Lin K, Wang H, Chen T, Li L, Huang J, Lin W, Zhu J, Li P, Fu X and Lin Z. Neuroprotective effect of apigenin against hypoxic-ischemic brain injury in neonatal rats activation of the PI3K/Akt/Nrf2 signaling pathway. (2021) Food Funct. Pubmed Food Funct

Das M and Devi KP. Dihydroactinidiolide regulates Nrf2/HO-1 expression and inhibits caspase-3/Bax pathway to protect SH-SY5Y human neuroblastoma cells from oxidative stress induced neuronal apoptosis. (2021) Neurotoxicology. Pubmed Neurotoxicology

Kim MB, Kang H, Li Y, Park YK and Lee JY. Fucoxanthin inhibits lipopolysaccharide-induced inflammation and oxidative stress by activating nuclear factor E2-related factor 2 via the phosphatidylinositol 3-kinase/AKT pathway in macrophages. (2021) Eur J Nutr. Pubmed Eur J Nutr

Hedrich WD and Wang H. Friend or Foe: Xenobiotic Activation of Nrf2 in Disease Control and Cardioprotection. (2021) Pharm Res. Pubmed Pharm Res

Lee D, Zhang MS, Tsang FH, Bao MH, Xu IM, Kit-Ho Lai R, Chiu DK, Tse AP, Law CT, Chan CY, Yuen VW, Chui NN, Oi-Lin Ng I, Wong CM and Wong CC. Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multi-layered Protection against ROS. (2021) Hepatology. Pubmed Hepatology

Talebi M, Talebi M, Farkhondeh T, Mishra G, İlgün S and Samarghandian S. New insights into the role of the Nrf2 signaling pathway in green tea catechin applications. (2021) Phytother Res. Pubmed Phytother Res

Li D, Hong X, Zhao F, Ci X and Zhang S. Targeting Nrf2 may reverse the drug resistance in ovarian cancer. (2021) Cancer Cell Int. 21, 116 Pubmed Cancer Cell Int PMC Article

Ma S, McGuire MH, Mangala LS, Lee S, Stur E, Hu W, Bayraktar E, Villar-Prados A, Ivan C, Wu SY, Yokoi A, Dasari SK, Jennings NB, Liu J, Lopez-Berestein G, Ram P and Sood AK. Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype. (2021) Cell Rep. 34, 108726 Pubmed Cell Rep

Ferraz-Bannitz R, Welendorf CR, Coelho PO, Salgado W, Nonino CB, Beraldo RA and Foss-Freitas MC. Bariatric surgery can acutely modulate ER-stress and inflammation on subcutaneous adipose tissue in non-diabetic patients with obesity. (2021) Diabetol Metab Syndr. 13, 19 Pubmed Diabetol Metab Syndr PMC Article

Nakajima M, Matsuyama M, Kawaguchi M, Kiwamoto T, Matsuno Y, Morishima Y, Yoshida K, Sherpa M, Yazaki K, Osawa H, Muratani M, Ishii Y and Hizawa N. Nrf2 Regulates Granuloma Formation and Macrophage Activation during Mycobacterium avium Infection via Mediating Nramp1 and HO-1 Expressions. (2021) mBio. 12, Pubmed mBio PMC Article

Peng D, Zaika A, Que J and El-Rifai W. The antioxidant response in Barrett's tumorigenesis: A double-edged sword. (2021) Redox Biol. 41, 101894 Pubmed Redox Biol

Mohamed ME, Abduldaium MS and Younis NS. Cardioprotective Effect of Linalool against Isoproterenol-Induced Myocardial Infarction. (2021) Life (Basel). 11, Pubmed Life (Basel)

Milne JV, Zhang BZ, Fujihara KM, Dawar S, Phillips WA and Clemons NJ. Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation. (2021) Sci Rep. 11, 4480 Pubmed Sci Rep

Soliman MM, Aldhahrani A, Elshazly SA, Shukry M and Abouzed TK. Borate Ameliorates Sodium Nitrite-Induced Oxidative Stress Through Regulation of Oxidant/Antioxidant Status: Involvement of the Nrf2/HO-1 and NF-κB Pathways. (2021) Biol Trace Elem Res. Pubmed Biol Trace Elem Res

Zhang H, Ge F, Shui X, Xiang Y, Wang X, Liao C and Wang J. NIX protein enhances antioxidant capacity of and reduces the apoptosis induced by HSP90 inhibitor luminespib/NVP-AUY922 in PC12 cells. (2021) Cell Stress Chaperones. Pubmed Cell Stress Chaperones

Qiu YH, Zhang TS, Wang XW, Wang MY, Zhao WX, Zhou HM, Zhang CH, Cai ML, Chen XF, Zhao WL and Shao RG. Mitochondria autophagy: a potential target for cancer therapy. (2021) J Drug Target. 1-16 Pubmed J Drug Target

Yang HL, Lin CP, Vudhya Gowrisankar Y, Huang PJ, Chang WL, Shrestha S and Hseu YC. The anti-melanogenic effects of ellagic acid through induction of autophagy in melanocytes and suppression of UVA-activated α-MSH pathways via Nrf2 activation in keratinocytes. (2021) Biochem Pharmacol. 185, 114454 Pubmed Biochem Pharmacol

Sekine H and Motohashi H. Roles of CNC Transcription Factors NRF1 and NRF2 in Cancer. (2021) Cancers (Basel). 13, Pubmed Cancers (Basel) PMC Article

Wallis KF, Morehead LC, Bird JT, Byrum S and Miousse IR. Differences in cell death in methionine versus cysteine depletion. (2021) Environ Mol Mutagen. Pubmed Environ Mol Mutagen

Li H, Gao C, Liu C, Liu L, Zhuang J, Yang J, Zhou C, Feng F, Sun C and Wu J. A review of the biological activity and pharmacology of cryptotanshinone, an important active constituent in Danshen. (2021) Biomed Pharmacother. 137, 111332 Pubmed Biomed Pharmacother

Meng M, Zhang R, Han R, Kong Y, Wang R and Hou L. The polysaccharides from the fruiting body prevent lipopolysaccharide/D-galactosamine-induced acute liver injury the miR-122-Nrf2/ARE pathways. (2021) Food Funct. Pubmed Food Funct

Elgohary S, Elkhodiry AA, Amin NS, Stein U and El Tayebi HM. Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients?. (2021) Cells. 10, Pubmed Cells

Kuscuoglu D, Bewersdorf L, Wenzel K, Gross A, Kobazi Ensari G, Luo Y, Kilic K, Hittatiya K, Golob-Schwarzl N, Leube RE, Preisinger C, George J, Metwally M, Eslam M, Lampertico P, Petta S, Mangia A, Berg T, Boonstra A, Brouwer WP, Abate ML, Loglio A, Sutton A, Nahon P, Schäfer B, Zoller H, Aigner E, Trautwein C, Haybaeck J and Strnad P. Dual proteotoxic stress accelerates liver injury via activation of p62-Nrf2. (2021) J Pathol. Pubmed J Pathol

Terasaki M, Takahashi S, Nishimura R, Kubota A, Kojima H, Ohta T, Hamada J, Kuramitsu Y, Maeda H, Miyashita K, Takahashi M and Mutoh M. A Marine Carotenoid of Fucoxanthinol Accelerates the Growth of Human Pancreatic Cancer PANC-1 Cells. (2021) Nutr Cancer. 1-16 Pubmed Nutr Cancer

Wang H, Lu J, Mandel JA, Zhang W, Schwalbe M, Gorka J, Liu Y, Marburger B, Wang J, Ranganathan S and Prochownik EV. Patient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggressive Murine Hepatoblastomas. (2021) Cell Mol Gastroenterol Hepatol. Pubmed Cell Mol Gastroenterol Hepatol

Mahn A and Castillo A. Potential of Sulforaphane as a Natural Immune System Enhancer: A Review. (2021) Molecules. 26, Pubmed Molecules PMC Article

Kaikini AA, Muke S, Peshattiwar V, Bagle S, Dighe V and Sathaye S. Ethyl ferulate, a lipophilic phenylpropanoid, prevents diabetes-associated renal injury in rats by amelioration of hyperglycemia-induced oxidative stress via activation of nuclear factor erythroid 2-related factor 2. (2021) J Food Biochem. e13607 Pubmed J Food Biochem

Zhu DC, Wang YH, Lin JH, Miao ZM, Xu JJ and Wu YS. Maltol inhibits the progression of osteoarthritis the nuclear factor-erythroid 2-related factor-2/heme oxygenase-1 signal pathway and . (2021) Food Funct. 12, 1327-1337 Pubmed Food Funct

Ali FEM, Hassanein EHM, El-Bahrawy AH, Omar ZMM, Rashwan EK, Abdel-Wahab BA and Abd-Elhamid TH. Nephroprotective effect of umbelliferone against cisplatin-induced kidney damage is mediated by regulation of NRF2, cytoglobin, SIRT1/FOXO-3, and NF- kB-p65 signaling pathways. (2021) J Biochem Mol Toxicol. e22738 Pubmed J Biochem Mol Toxicol

Zhang Y, Wei Z, Yang M, Liu D, Pan M, Wu C, Zhang W and Mai K. Dietary taurine modulates hepatic oxidative status, ER stress and inflammation in juvenile turbot (Scophthalmus maximus L.) fed high carbohydrate diets. (2021) Fish Shellfish Immunol. 109, 1-11 Pubmed Fish Shellfish Immunol

Sheng Y, Yang G, Casey K, Curry S, Oliver M, Han SM, Leeuwenburgh C and Xiao R. A novel role of the mitochondrial iron-sulfur cluster assembly protein ISCU-1/ISCU in longevity and stress response. (2021) Geroscience. Pubmed Geroscience

Tao J, Krutsenko Y, Moghe A, Singh S, Poddar M, Bell A, Oertel M, Singhi AD, Geller D, Chen X, Lujambio A, Liu S and Monga SP. Nrf2 and β-catenin coactivation in hepatocellular cancer: Biological and therapeutic implications. (2021) Hepatology. Pubmed Hepatology

Dar AA, Fehaid A, Alkhatani S, Alarifi S, Alqahtani WS, Albasher G, Almeer R, Alfarraj S and Moneim AA. The protective role of luteolin against the methotrexate-induced hepato-renal toxicity via its antioxidative, anti-inflammatory, and anti-apoptotic effects in rats. (2021) Hum Exp Toxicol. 960327121991905 Pubmed Hum Exp Toxicol

Ibor OR, Khan EA and Arukwe A. Toxicity assessment of Lemna solid waste dumpsite (Calabar, Nigeria) using different extraction methods and toxicological responses of PLHC-1 cells. (2021) Environ Toxicol Pharmacol. 82, 103554 Pubmed Environ Toxicol Pharmacol

Lei S, Wu S, Wang G, Li B, Liu B and Lei X. Pinoresinol diglucoside attenuates neuroinflammation, apoptosis and oxidative stress in a mice model with Alzheimer's disease. (2021) Neuroreport. 32, 259-267 Pubmed Neuroreport

Kumar N, Perez-Novo C, Shaw P, Logie E, Privat-Maldonado A, Dewilde S, Smits E, Berghe WV and Bogaerts A. Physical plasma-derived oxidants sensitize pancreatic cancer cells to ferroptotic cell death. (2021) Free Radic Biol Med. Pubmed Free Radic Biol Med

Panieri E and Saso L. Inhibition of the NRF2/KEAP1 Axis: A Promising Therapeutic Strategy to Alter Redox Balance of Cancer Cells. (2021) Antioxid Redox Signal. Pubmed Antioxid Redox Signal

Wang Z, Sun X, Feng Y, Wang Y, Zhang L, Wang Y, Fang Z, Azami NLB, Sun M and Li Q. Dihydromyricetin reverses MRP2-induced multidrug resistance by preventing NF-κB-Nrf2 signaling in colorectal cancer cell. (2021) Phytomedicine. 82, 153414 Pubmed Phytomedicine

Meng C, Zhan J, Chen D, Shao G, Zhang H, Gu W and Luo J. The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2. (2021) Oncogene. Pubmed Oncogene

Cao X, Chen XM, Xiao WZ, Li B, Zhang B, Wu Q and Xue Q. ROS‑mediated hypomethylation of PRDX5 promotes STAT3 binding and activates the Nrf2 signaling pathway in NSCLC. (2021) Int J Mol Med. 47, 573-582 Pubmed Int J Mol Med PMC Article

Zhang MH, Li J, Zhu XY, Zhang YQ, Ye ST, Leng YR, Yang T, Zhang H and Kong LY. Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress. (2021) Free Radic Biol Med. 164, 1-12 Pubmed Free Radic Biol Med

Li N, Wang J, Zang X, Wang Z, Zhang T, Zhao B, Miao J and Lin Z. HS probe CPC inhibits autophagy and promotes apoptosis by inhibiting glutathionylation of Keap1 at Cys434. (2021) Apoptosis. 26, 111-131 Pubmed Apoptosis

Yang G, Xiang Y, Zhou W, Zhong X, Zhang Y, Lin D and Huang X. 1-Bromopropane-induced apoptosis in OVCAR-3 cells via oxidative stress and inactivation of Nrf2. (2021) Toxicol Ind Health. 37, 59-67 Pubmed Toxicol Ind Health

Xiao S, Liu N, Yang X, Ji G and Li M. Polygalacin D suppresses esophageal squamous cell carcinoma growth and metastasis through regulating miR-142-5p/Nrf2 axis. (2021) Free Radic Biol Med. 164, 58-75 Pubmed Free Radic Biol Med

Dun Su , Wang X, Ma Y, Hao J, Jinshen Wang , Yongqu Lu , Yulin Liu , Xingfang Wang and Zhang L. Nrf2-induced miR-23a-27a-24-2 cluster modulates damage repair of intestinal mucosa by targeting the Bach1/HO-1 axis in inflammatory bowel diseases. (2021) Free Radic Biol Med. 163, 1-9 Pubmed Free Radic Biol Med

Chen G, Chang W, Li X, Han L, Zhou D, Feng Y, Li B, Zhu F and Li N. n-BuOH extract of Bletilla striata exerts chemopreventive effects on lung against SiO nanoparticles through activation of Nrf2 pathway. (2021) Phytomedicine. 82, 153445 Pubmed Phytomedicine

Li Z, Bi H, Jiang H, Song J, Meng Q, Zhang Y and Fei X. Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice. (2021) Mol Med Rep. 23, 1 Pubmed Mol Med Rep PMC Article

Krajka-Kuźniak V, Paluszczak J, Kleszcz R and Baer-Dubowska W. (+)-Usnic acid modulates the Nrf2-ARE pathway in FaDu hypopharyngeal carcinoma cells. (2021) Mol Cell Biochem. Pubmed Mol Cell Biochem

Panigrahi DP, Bhol CS, Nivetha R, Nagini S, Patil S, Maiti TK and Bhutia SK. Corrigendum to "Abrus agglutinin inhibits oral carcinogenesis through inactivation of NRF2 signaling pathway" [Int J Biol Macromol. 2020; 155:1123-1132.]. (2021) Int J Biol Macromol. 169, 599-600 Pubmed Int J Biol Macromol

Al Mamun A, Wu Y, Monalisa I, Jia C, Zhou K, Munir F and Xiao J. Role of pyroptosis in spinal cord injury and its therapeutic implications. (2021) J Adv Res. 28, 97-109 Pubmed J Adv Res PMC Article

Cheng X, Aabdin ZU, Wang Y, Ma N, Dai H, Shi X and Shen X. Glutamine pretreatment protects bovine mammary epithelial cells from inflammation and oxidative stress induced by γ-d-glutamyl-meso-diaminopimelic acid (iE-DAP). (2021) J Dairy Sci. 104, 2123-2139 Pubmed J Dairy Sci

Sano A, Maehara T and Fujimori K. Protection of 6-OHDA neurotoxicity by PGF through FP-ERK-Nrf2 signaling in SH-SY5Y cells. (2021) Toxicology. 450, 152686 Pubmed Toxicology

Song X, Tan L, Wang M, Ren C, Guo C, Yang B, Ren Y, Cao Z, Li Y and Pei J. Myricetin: A review of the most recent research. (2021) Biomed Pharmacother. 134, 111017 Pubmed Biomed Pharmacother

He H, Ma Y, Huang H, Huang C, Chen Z, Chen D, Gu Y, Wang X and Chen J. A comprehensive understanding about the pharmacological effect of diallyl disulfide other than its anti-carcinogenic activities. (2021) Eur J Pharmacol. 893, 173803 Pubmed Eur J Pharmacol

Purohit V, Wang L, Yang H, Li J, Ney GM, Gumkowski ER, Vaidya AJ, Wang A, Bhardwaj A, Zhao E, Dolgalev I, Zamperone A, Abel EV, Magliano MPD, Crawford HC, Diolaiti D, Papagiannakopoulos TY, Lyssiotis CA and Simeone DM. ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer. (2021) Genes Dev. 35, 218-233 Pubmed Genes Dev PMC Article

Ashrafizadeh M, Zarrabi A, Orouei S, Kiavash Hushmandi , Hakimi A, Amirhossein Zabolian , Daneshi S, Samarghandian S, Baradaran B and Najafi M. MicroRNA-mediated autophagy regulation in cancer therapy: The role in chemoresistance/chemosensitivity. (2021) Eur J Pharmacol. 892, 173660 Pubmed Eur J Pharmacol

Cheng J, Xu T, Xun C, Guo H, Cao R, Gao S and Sheng W. Carnosic acid protects against ferroptosis in PC12 cells exposed to erastin through activation of Nrf2 pathway. (2021) Life Sci. 266, 118905 Pubmed Life Sci

Wang Q, Gu T, Ma L, Bu S, Zhou W, Mao G, Wang LL, Guo Y and Lai D. Efficient iron utilization compensates for loss of extracellular matrix of ovarian cancer spheroids. (2021) Free Radic Biol Med. 164, 369-380 Pubmed Free Radic Biol Med

Li J, Yang C and Wang Y. miR‑126 overexpression attenuates oxygen‑glucose deprivation/reperfusion injury by inhibiting oxidative stress and inflammatory response via the activation of SIRT1/Nrf2 signaling pathway in human umbilical vein endothelial cells. (2021) Mol Med Rep. 23, 1 Pubmed Mol Med Rep PMC Article

Okazaki K, Anzawa H, Liu Z, Ota N, Kitamura H, Onodera Y, Alam MM, Matsumaru D, Suzuki T, Katsuoka F, Tadaka S, Motoike I, Watanabe M, Hayasaka K, Sakurada A, Okada Y, Yamamoto M, Suzuki T, Kinoshita K, Sekine H and Motohashi H. Publisher Correction: Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers. (2021) Nat Commun. 12, 506 Pubmed Nat Commun PMC Article

Zhang F, Shao C, Chen Z, Li Y, Jing X and Huang Q. Low Dose of Trichostatin A Improves Radiation Resistance by Activating Akt/Nrf2-Dependent Antioxidation Pathway in Cancer Cells. (2021) Radiat Res. Pubmed Radiat Res

Land Lail H, Feresin RG, Hicks D, Stone B, Price E and Wanders D. Berries as a Treatment for Obesity-Induced Inflammation: Evidence from Preclinical Models. (2021) Nutrients. 13, Pubmed Nutrients

Musso N, Caruso G, Bongiorno D, Grasso M, Bivona DA, Campanile F, Caraci F and Stefani S. Different Modulatory Effects of Four Methicillin-Resistant Clones on MG-63 Osteoblast-Like Cells. (2021) Biomolecules. 11, Pubmed Biomolecules PMC Article

Nemmar A, Al-Salam S, Nuaman SA, Kazim M, Mohamed F, Beegam S, Yuvaraju P, Yasin J and Ali BH. Exacerbation of Coagulation and Cardiac Injury in Rats with Cisplatin-Induced Nephrotoxicity Following Intratracheal Instillation of Cerium Oxide Nanoparticles. (2021) Cell Physiol Biochem. 55, 1-16 Pubmed Cell Physiol Biochem

Veres B, Eros K, Antus C, Kalman N, Fonai F, Jakus PB, Boros E, Hegedus Z, Nagy I, Tretter L, Gallyas F and Sumegi B. Cyclophilin D-dependent mitochondrial permeability transition amplifies inflammatory reprogramming in endotoxemia. (2021) FEBS Open Bio. Pubmed FEBS Open Bio

Ashrafizadeh M, Rafiei H, Mohammadinejad R, Farkhondeh T and Samarghandian S. Anti-tumor activity of resveratrol against gastric cancer: a review of recent advances with an emphasis on molecular pathways. (2021) Cancer Cell Int. 21, 66 Pubmed Cancer Cell Int PMC Article

Joshi P, Joshi S, Semwal D, Bisht A, Paliwal S, Dwivedi J and Sharma S. Curcumin: An Insight to Molecular Pathways Involved in Anticancer Activity. (2021) Mini Rev Med Chem. Pubmed Mini Rev Med Chem

Wang F, Zhang Y, Shen J, Yang B, Dai W, Yan J, Maimouni S, Daguplo HQ, Coppola S, Gao Y, Wang Y, Du Z, Peng K, Liu H, Zhang Q, Tang F, Wang P, Gao S, Wang Y, Ding WX, Guo G, Wang F and Zong WX. The Ubiquitin E3 Ligase TRIM21 Promotes Hepatocarcinogenesis by Suppressing the p62-Keap1-Nrf2 Antioxidant Pathway. (2021) Cell Mol Gastroenterol Hepatol. Pubmed Cell Mol Gastroenterol Hepatol

Hemmati M, Yousefi B, Bahar A and Eslami M. Importance of Heme Oxygenase-1 in Gastrointestinal Cancers: Functions, Inductions, Regulations, and Signaling. (2021) J Gastrointest Cancer. Pubmed J Gastrointest Cancer

Küper A, Baumann J, Göpelt K, Baumann M, Sänger C, Metzen E, Kranz P and Brockmeier U. Overcoming hypoxia-induced resistance of pancreatic and lung tumor cells by disrupting the PERK-NRF2-HIF-axis. (2021) Cell Death Dis. 12, 82 Pubmed Cell Death Dis PMC Article

Hu Q, Zhang W, Wu Z, Tian X, Xiang J, Li L, Li Z, Peng X, Wei S, Ma X and Zhao Y. Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects. (2021) Pharmacol Res. 105444 Pubmed Pharmacol Res

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