English: Graph of Nrf2 publications (pubmed se...

English: Graph of Nrf2 publications (pubmed search) by year (Photo credit: Wikipedia)

There are currently over 2300 articles (peer reviewed clinical reviews and studies) on Pubmed.gov on the topic of NRF2 Activation. There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to Pubmed.gov and type in the name of their product. Pubmed is a website operated by the National Institute of Health (NIH).  PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources. Last 200 NRF-2 Studies published on Pubmed
Thai SF, Jones CP, Robinette BL, Ren H, Vallant B, Fisher A and Kitchin KT. Effects of Copper Nanoparticles on mRNA and Small RNA Expression in Human Hepatocellular Carcinoma (HepG2) Cells. (2021) J Nanosci Nanotechnol. 21, 5083-5098 Pubmed J Nanosci Nanotechnol
Liu P, Yin Z, Chen M, Huang C, Wu Z, Huang J, Ou S and Zheng J. Cytotoxicity of adducts formed between quercetin and methylglyoxal in PC-12 cells. (2021) Food Chem. 352, 129424 Pubmed Food Chem
Xiang D, Yang J, Xu Y, Lan L, Li G, Zhang C and Liu D. Estrogen cholestasis induces gut and liver injury in rats involving in activating PI3K/Akt and MAPK signaling pathways. (2021) Life Sci. 276, 119367 Pubmed Life Sci
Brasil FB, Bertolini Gobbo RC, Souza de Almeida FJ, Luckachaki MD, Dall'Oglio EL and de Oliveira MR. The signaling pathway PI3K/Akt/Nrf2/HO-1 plays a role in the mitochondrial protection promoted by astaxanthin in the SH-SY5Y cells exposed to hydrogen peroxide. (2021) Neurochem Int. 146, 105024 Pubmed Neurochem Int
Zhang B, Kirn LA and Burke R. The Vhl E3 ubiquitin ligase complex regulates melanisation via sima, cnc and the copper import protein Ctr1A. (2021) Biochim Biophys Acta Mol Cell Res. 1868, 119022 Pubmed Biochim Biophys Acta Mol Cell Res
Yoshida GJ and Saya H. Molecular pathology underlying the robustness of cancer stem cells. (2021) Regen Ther. 17, 38-50 Pubmed Regen Ther PMC Article
Ali FEM, Sayed AM, El-Bahrawy AH, Omar ZMM and Hassanein EHM. Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity. (2021) Life Sci. 275, 119349 Pubmed Life Sci
Shan HJ, Zhu LQ, Yao C, Zhang ZQ, Liu YY, Jiang Q, Zhou XZ, Wang XD and Cao C. MAFG-driven osteosarcoma cell progression is inhibited by a novel miRNA miR-4660. (2021) Mol Ther Nucleic Acids. 24, 385-402 Pubmed Mol Ther Nucleic Acids PMC Article
Liu M, Zheng B, Liu P, Zhang J, Chu X, Dong C, Shi J, Liang Y, Chu L, Liu Y and Han X. Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury. (2021) Mol Med Rep. 23, Pubmed Mol Med Rep PMC Article
Rajput SA, Wang XQ and Yan HC. Morin hydrate: A comprehensive review on novel natural dietary bioactive compound with versatile biological and pharmacological potential. (2021) Biomed Pharmacother. 138, 111511 Pubmed Biomed Pharmacother
Xiao N, Zhao Y, He W, Yao Y, Wu N, Xu M, Du H and Tu Y. Egg yolk oils exert anti-inflammatory effect via regulating Nrf2/NF-κB pathway. (2021) J Ethnopharmacol. 274, 114070 Pubmed J Ethnopharmacol
Oh S, Tsujimoto T, Kim B, Uchida F, Suzuki H, Iizumi S, Isobe T, Sakae T, Tanaka K and Shoda J. Weight-loss-independent benefits of exercise on liver steatosis and stiffness in Japanese men with NAFLD. (2021) JHEP Rep. 3, 100253 Pubmed JHEP Rep PMC Article
. Autophagy-Deficient Pancreatic Cancer Cells Depend on Macropinocytosis. (2021) Cancer Discov. 11, OF28 Pubmed Cancer Discov
Ge MH, Tian H, Mao L, Li DY, Lin JQ, Hu HS, Huang SC, Zhang CJ and Mei XF. Zinc attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury by activating Nrf2/GPX4 defense pathway. (2021) CNS Neurosci Ther. Pubmed CNS Neurosci Ther
Arab HH, Eid AH, Mahmoud AM and Senousy MA. Linagliptin mitigates experimental inflammatory bowel disease in rats by targeting inflammatory and redox signaling. (2021) Life Sci. 273, 119295 Pubmed Life Sci
Li X, Zhou L, Zhang Y, He X, Lu H, Zhang L, Tian Y, Liu X, Zheng H, Shao J and Long M. mGPDH Deficiency leads to melanoma metastasis via induced NRF2. (2021) J Cell Mol Med. Pubmed J Cell Mol Med
Jiang C, Li R, Xiu C, Ma X, Hu H, Wei L, Tang Y, Tao M and Zhao J. Upregulating CXCR7 accelerates endothelial progenitor cell-mediated endothelial repair by activating Akt/Keap-1/Nrf2 signaling in diabetes mellitus. (2021) Stem Cell Res Ther. 12, 264 Pubmed Stem Cell Res Ther
Jin L and Tong L. PAQR3 inhibits proliferation and aggravates ferroptosis in acute lymphoblastic leukemia through modulation Nrf2 stability. (2021) Immun Inflamm Dis. Pubmed Immun Inflamm Dis
Liu T, Lv YF, Zhao JL, You QD and Jiang ZY. Regulation of Nrf2 by phosphorylation: Consequences for biological function and therapeutic implications. (2021) Free Radic Biol Med. 168, 129-141 Pubmed Free Radic Biol Med
Liu J, Qin X, Ma W, Jia S, Zhang X, Yang X, Pan D and Jin F. Corilagin induces apoptosis and autophagy in NRF2‑addicted U251 glioma cell line. (2021) Mol Med Rep. 23, Pubmed Mol Med Rep PMC Article
Kalezic A, Udicki M, Srdic Galic B, Aleksic M, Korac A, Jankovic A and Korac B. Redox profile of breast tumor and associated adipose tissue in premenopausal women - Interplay between obesity and malignancy. (2021) Redox Biol. 41, 101939 Pubmed Redox Biol PMC Article
Yue CF, Li LS, Ai L, Deng JK and Guo YM. sMicroRNA-28-5p acts as a metastasis suppressor in gastric cancer by targeting Nrf2. (2021) Exp Cell Res. 402, 112553 Pubmed Exp Cell Res
Schmidlin CJ, Tian W, Dodson M, Chapman E and Zhang DD. FAM129B-dependent activation of NRF2 promotes an invasive phenotype in BRAF mutant melanoma cells. (2021) Mol Carcinog. 60, 331-341 Pubmed Mol Carcinog
Su X, Wang S, Zhang H, Yang G, Bai Y, Liu P, Meng L, Jiang X and Xin Y. Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 through epigenetic modification. (2021) J Cell Mol Med. 25, 4408-4419 Pubmed J Cell Mol Med
Addison R, Weatherhead SC, Pawitri A, Smith GR, Rider A, Grantham HJ, Cockell SJ and Reynolds NJ. Therapeutic wavelengths of ultraviolet B radiation activate apoptotic, circadian rhythm, redox signalling and key canonical pathways in psoriatic epidermis. (2021) Redox Biol. 41, 101924 Pubmed Redox Biol PMC Article
Yuan T, Sun J, Tian J, Hu J, Yin H and Yin J. Involvement of ABC transporters in the detoxification of non-substrate nanoparticles in lung and cervical cancer cells. (2021) Toxicology. 455, 152762 Pubmed Toxicology
Calabrese EJ, Priest ND and Kozumbo WJ. Thresholds for carcinogens. (2021) Chem Biol Interact. 341, 109464 Pubmed Chem Biol Interact
Pei X, Jiang H, Liu X, Li L, Li C, Xiao X, Li D and Tang S. Targeting HMGB1 inhibits T-2 toxin-induced neurotoxicity via regulation of oxidative stress, neuroinflammation and neuronal apoptosis. (2021) Food Chem Toxicol. 151, 112134 Pubmed Food Chem Toxicol
Sun J, Zhou C, Zhao Y, Zhang X, Chen W, Zhou Q, Hu B, Gao D, Raatz L, Wang Z, Nelson PJ, Jiang Y, Ren N, Bruns CJ and Zhou H. Quiescin sulfhydryl oxidase 1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by driving EGFR endosomal trafficking and inhibiting NRF2 activation. (2021) Redox Biol. 41, 101942 Pubmed Redox Biol PMC Article
Abdel-Wahab BA, Walbi IA, Albarqi HA, Ali FEM and Hassanein EHM. Roflumilast protects from cisplatin-induced testicular toxicity in male rats and enhances its cytotoxicity in prostate cancer cell line. Role of NF-κB-p65, cAMP/PKA and Nrf2/HO-1, NQO1 signaling. (2021) Food Chem Toxicol. 151, 112133 Pubmed Food Chem Toxicol
Sampath C, Wilus D, Tabatabai M, Freeman ML and Gangula PR. Mechanistic role of antioxidants in rescuing delayed gastric emptying in high fat diet induced diabetic female mice. (2021) Biomed Pharmacother. 137, 111370 Pubmed Biomed Pharmacother PMC Article
Mirzaei S, Mohammadi AT, Gholami MH, Hashemi F, Zarrabi A, Zabolian A, Hushmandi K, Makvandi P, Samec M, Liskova A, Kubatka P, Nabavi N, Aref AR, Ashrafizadeh M, Khan H and Najafi M. Nrf2 signaling pathway in cisplatin chemotherapy: Potential involvement in organ protection and chemoresistance. (2021) Pharmacol Res. 167, 105575 Pubmed Pharmacol Res
Ross D and Siegel D. The diverse functionality of NQO1 and its roles in redox control. (2021) Redox Biol. 41, 101950 Pubmed Redox Biol PMC Article
Cen M, Ouyang W, Zhang W, Yang L, Lin X, Dai M, Hu H, Tang H, Liu H, Xia J and Xu F. MitoQ protects against hyperpermeability of endothelium barrier in acute lung injury via a Nrf2-dependent mechanism. (2021) Redox Biol. 41, 101936 Pubmed Redox Biol PMC Article
Guo JW, Cheng YP, Liu CY, Thong HY, Lo Y, Wu CY and Jee SH. Magnolol may contribute to barrier function improvement on imiquimod-induced psoriasis-like dermatitis animal model via the downregulation of interleukin-23. (2021) Exp Ther Med. 21, 448 Pubmed Exp Ther Med PMC Article
Dong W, Liu G, Zhang K, Tan Y, Zou H, Yuan Y, Gu J, Song R, Zhu J and Liu Z. Cadmium exposure induces rat proximal tubular cells injury via p62-dependent Nrf2 nucleus translocation mediated activation of AMPK/AKT/mTOR pathway. (2021) Ecotoxicol Environ Saf. 214, 112058 Pubmed Ecotoxicol Environ Saf
Xu Y, Tu W, Sun D, Chen X, Ge Y, Yao S, Li B, Zhenbo Zhang and Liu Y. Nrf2 alleviates radiation-induced rectal injury by inhibiting of necroptosis. (2021) Biochem Biophys Res Commun. 554, 49-55 Pubmed Biochem Biophys Res Commun
Bader S, Wilmers J, Pelzer M, Jendrossek V and Rudner J. Activation of anti-oxidant Keap1/Nrf2 pathway modulates efficacy of dihydroartemisinin-based monotherapy and combinatory therapy with ionizing radiation. (2021) Free Radic Biol Med. 168, 44-54 Pubmed Free Radic Biol Med
Kohandel Z, Farkhondeh T, Aschner M and Samarghandian S. Nrf2 a molecular therapeutic target for Astaxanthin. (2021) Biomed Pharmacother. 137, 111374 Pubmed Biomed Pharmacother
Consonni FM, Bleve A, Totaro MG, Storto M, Kunderfranco P, Termanini A, Pasqualini F, Alì C, Pandolfo C, Sgambelluri F, Grazia G, Santinami M, Maurichi A, Milione M, Erreni M, Doni A, Fabbri M, Gribaldo L, Rulli E, Soares MP, Torri V, Mortarini R, Anichini A and Sica A. Heme catabolism by tumor-associated macrophages controls metastasis formation. (2021) Nat Immunol. 22, 595-606 Pubmed Nat Immunol
Liu P, Li J, Liu M, Zhang M, Xue Y, Zhang Y, Han X, Jing X and Chu L. Hesperetin modulates the Sirt1/Nrf2 signaling pathway in counteracting myocardial ischemia through suppression of oxidative stress, inflammation, and apoptosis. (2021) Biomed Pharmacother. 139, 111552 Pubmed Biomed Pharmacother
Ayoup MS, Abu-Serie MM, Abdel-Hamid H and Teleb M. Beyond direct Nrf2 activation; reinvestigating 1,2,4-oxadiazole scaffold as a master key unlocking the antioxidant cellular machinery for cancer therapy. (2021) Eur J Med Chem. 220, 113475 Pubmed Eur J Med Chem
Wang Q, Bin C, Xue Q, Gao Q, Huang A, Wang K and Tang N. GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis. (2021) Cell Death Dis. 12, 426 Pubmed Cell Death Dis
Lei L, Guo Y, Lin J, Lin X, He S, Qin Z and Lin Q. Inhibition of endotoxin-induced acute lung injury in rats by bone marrow-derived mesenchymal stem cells: Role of Nrf2/HO-1 signal axis in inhibition of NLRP3 activation. (2021) Biochem Biophys Res Commun. 551, 7-13 Pubmed Biochem Biophys Res Commun
Sezgin-Bayindir Z, Losada-Barreiro S, Bravo-Díaz C, Sova M, Kristl J and Saso L. Nanotechnology-Based Drug Delivery to Improve the Therapeutic Benefits of NRF2 Modulators in Cancer Therapy. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel)
Consoli V, Sorrenti V, Grosso S and Vanella L. Heme Oxygenase-1 Signaling and Redox Homeostasis in Physiopathological Conditions. (2021) Biomolecules. 11, Pubmed Biomolecules PMC Article
Qin S, He X, Lin H, Schulte BA, Zhao M, Tew KD and Wang GY. Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair. (2021) Free Radic Biol Med. 169, 238-247 Pubmed Free Radic Biol Med
Kulkarni A, McDermott JR, Kathad U, Modali R, Richard JP, Sharma P and Bhatia K. The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations. (2021) Oncotarget. 12, 791-806 Pubmed Oncotarget PMC Article
Yue CF, Li LS, Ai L, Deng JK and Guo YM. Corrigendum to "sMicroRNA-28-5p acts as a metastasis suppressor in gastric cancer by targeting Nrf2". (2021) Exp Cell Res. 112616 Pubmed Exp Cell Res
Majumder D, Debnath R, Nath P, Libin Kumar KV, Debnath M, Tribedi P and Maiti D. Bromelain and Olea europaea (L.) leaf extract mediated alleviation of benzo(a)pyrene induced lung cancer through Nrf2 and NFκB pathway. (2021) Environ Sci Pollut Res Int. Pubmed Environ Sci Pollut Res Int
Mao M, Yang L, Hu J, Liu B, Liu C, Zhang X, Liu Y, Wang P and Li H. OCT3/4 enhances tumor immune response by upregulating the TET1-dependent NRF2/MDM2 axis in bladder cancer. (2021) Genomics. Pubmed Genomics
Zhang Z and Costa M. p62 functions as a signal hub in metal carcinogenesis. (2021) Semin Cancer Biol. Pubmed Semin Cancer Biol
Tang Z, Ju Y, Dai X, Ni N, Liu Y, Zhang D, Gao H, Sun H, Zhang J and Gu P. HO-1-mediated ferroptosis as a target for protection against retinal pigment epithelium degeneration. (2021) Redox Biol. 43, 101971 Pubmed Redox Biol
Bi Z, Zhang Q, Fu Y, Seno A, Wadgaonkar P, Qiu Y, Almutairy B, Xu L, Zhang W, Thakur C and Chen F. Cooperation between NRF2-mediated transcription and MDIG-dependent epigenetic modifications in arsenic-induced carcinogenesis and cancer stem cells. (2021) Semin Cancer Biol. Pubmed Semin Cancer Biol
Sriramajayam K, Peng D, Lu H, Zhou S, Bhat N, McDonald OG, Que J, Zaika A and El-Rifai W. Activation of NRF2 by APE1/REF1 is redox-dependent in Barrett's related esophageal adenocarcinoma cells. (2021) Redox Biol. 43, 101970 Pubmed Redox Biol
Harris CM, Zamperoni KE, Sernoskie SC, Chow NSM and Massey TE. Effects of in vivo treatment of mice with sulforaphane on repair of DNA pyridyloxylbutylation. (2021) Toxicology. 454, 152753 Pubmed Toxicology
Jin M, Yang Y, Dai Y, Cai R, Wu L, Jiao Y, Zhang Z, Yang H, Zhou Y, Tang L, Li L and Li Y. 27-Hydroxycholesterol is a specific factor in the neoplastic microenvironment of HCC that causes MDR via GRP75 regulation of the redox balance and metabolic reprogramming. (2021) Cell Biol Toxicol. Pubmed Cell Biol Toxicol
Chang M, Wilson CJ, Karunatilleke NC, Moselhy MH, Karttunen M and Choy WY. Exploring the Conformational Landscape of the Neh4 and Neh5 Domains of Nrf2 Using Two Different Force Fields and Circular Dichroism. (2021) J Chem Theory Comput. Pubmed J Chem Theory Comput
Hill KS, McDowell A, McCorkle JR, Schuler E, Ellingson SR, Plattner R and Kolesar JM. KEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung Cancer. (2021) Cancers (Basel). 13, Pubmed Cancers (Basel) PMC Article
Poznanski SM, Singh K, Ritchie TM, Aguiar JA, Fan IY, Portillo AL, Rojas EA, Vahedi F, El-Sayes A, Xing S, Butcher M, Lu Y, Doxey AC, Schertzer JD, Hirte HW and Ashkar AA. Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment. (2021) Cell Metab. Pubmed Cell Metab
Stefan J, Kim TK, Schedel F, Janjetovic Z, Crossman DK, Steinbrink K, Slominski RM, Zmijewski J, Tulic MK, Reiter RJ, Kleszczyński K and Slominski AT. Differential and Overlapping Effects of Melatonin and Its Metabolites on Keratinocyte Function: Bioinformatics and Metabolic Analyses. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article
Miller HE and Bishop AJR. Correlation AnalyzeR: functional predictions from gene co-expression correlations. (2021) BMC Bioinformatics. 22, 206 Pubmed BMC Bioinformatics PMC Article
Kang Q, Tong Y, Gowd V, Wang M, Chen F and Cheng KW. Oral administration of EGCG solution equivalent to daily achievable dosages of regular tea drinkers effectively suppresses miR483-3p induced metastasis of hepatocellular carcinoma cells in mice. (2021) Food Funct. 12, 3381-3392 Pubmed Food Funct
Feng L, Chen M, Li Y, Li M, Hu S, Zhou B, Zhu L, Yu L, Zhou Q, Tan L, An H, Wang X and Jin H. Sirt1 deacetylates and stabilizes p62 to promote hepato-carcinogenesis. (2021) Cell Death Dis. 12, 405 Pubmed Cell Death Dis PMC Article
Su H, Yang F, Sun B and Karin M. Macropinocytosis: the big drinker behind cancer cell self-consumption. (2021) Autophagy. 1-2 Pubmed Autophagy
Wu Y, Chen H, Zou Y, Yi R, Mu J and Zhao X. Lactobacillus plantarum HFY09 alleviates alcohol-induced gastric ulcers in mice via an anti-oxidative mechanism. (2021) J Food Biochem. e13726 Pubmed J Food Biochem
Ahmed SA and Mohammed WI. Carvedilol induces the antiapoptotic proteins Nrf and Bcl and inhibits cellular apoptosis in aluminum-induced testicular toxicity in male Wistar rats. (2021) Biomed Pharmacother. 139, 111594 Pubmed Biomed Pharmacother
Buha A, Baralić K, Djukic-Cosic D, Bulat Z, Tinkov A, Panieri E and Saso L. The Role of Toxic Metals and Metalloids in Nrf2 Signaling. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel)
Kabel AM, Arab HH and Abd Elmaaboud MA. Attenuation of diethyl nitrosamine-induced hepatocellular carcinoma by taxifolin and/or alogliptin: The interplay between toll-like receptor 4, transforming growth factor beta-1, and apoptosis. (2021) Hum Exp Toxicol. 9603271211008496 Pubmed Hum Exp Toxicol
Mirzaei S, Hushmandi K, Zabolian A, Saleki H, Torabi SMR, Ranjbar A, SeyedSaleh S, Sharifzadeh SO, Khan H, Ashrafizadeh M, Zarrabi A and Ahn KS. Elucidating Role of Reactive Oxygen Species (ROS) in Cisplatin Chemotherapy: A Focus on Molecular Pathways and Possible Therapeutic Strategies. (2021) Molecules. 26, Pubmed Molecules PMC Article
Cheng X, Liu D, Song H, Tian X, Yan C and Han Y. Overexpression of Kininogen-1 aggravates oxidative stress and mitochondrial dysfunction in DOX-induced cardiotoxicity. (2021) Biochem Biophys Res Commun. 550, 142-150 Pubmed Biochem Biophys Res Commun
Ekuban FA, Zong C, Takikawa M, Morikawa K, Sakurai T, Ichihara S, Itoh K, Yamamoto M, Ohsako S and Ichihara G. Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. (2021) Toxicology. 456, 152785 Pubmed Toxicology
Song MY, Lee DY, Chun KS and Kim EH. The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci
Gupta P and Mohanty D. SMMPPI: a machine learning-based approach for prediction of modulators of protein-protein interactions and its application for identification of novel inhibitors for RBD:hACE2 interactions in SARS-CoV-2. (2021) Brief Bioinform. Pubmed Brief Bioinform PMC Article
Ji SY, Cha HJ, Molagoda IMN, Kim MY, Kim SY, Hwangbo H, Lee H, Kim GY, Kim DH, Hyun JW, Kim HS, Kim S, Jin CY and Choi YH. Suppression of Lipopolysaccharide-Induced Inflammatory and Oxidative Response by 5-Aminolevulinic Acid in RAW 264.7 Macrophages and Zebrafish Larvae. (2021) Biomol Ther (Seoul). Pubmed Biomol Ther (Seoul)
Hammad AM, Swiss GMS, Hall FS, Hikmat S, Sari Y, Al-Qirim TM and Amawi HA. Ceftriaxone Reduces Waterpipe Tobacco Smoke Withdrawal-induced Anxiety in rats via Modulating the Expression of TNF-α/NFĸB, Nrf2, and GLT-1. (2021) Neuroscience. 463, 128-142 Pubmed Neuroscience
Kulkarni N, Gadde R, Gugnani KS, Vu N, Yoo C, Zaveri R and Betharia S. Neuroprotective effects of disubstituted dithiolethione ACDT against manganese-induced toxicity in SH-SY5Y cells. (2021) Neurochem Int. 147, 105052 Pubmed Neurochem Int
Cao H, Zhang L, Qu Z, Tian S, Wang Z, Jiang Y, Hou Q, Jia L and Wang W. The protective effect of hydroxylated fullerene pretreatment on pilocarpine-induced status epilepticus. (2021) Brain Res. 1764, 147468 Pubmed Brain Res
Zeng H, Zhao X and Tang C. Downregulation of SELENBP1 enhances oral squamous cell carcinoma chemoresistance through KEAP1-NRF2 signaling. (2021) Cancer Chemother Pharmacol. Pubmed Cancer Chemother Pharmacol
Leon LM, Gautier M, Allan R, Ilié M, Nottet N, Pons N, Paquet A, Lebrigand K, Truchi M, Fassy J, Magnone V, Kinnebrew G, Radovich M, Cheok MH, Barbry P, Vassaux G, Marquette CH, Ponzio G, Ivan M, Pottier N, Hofman P, Mari B and Rezzonico R. Correction: The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress. (2021) Oncogene. 40, 2621 Pubmed Oncogene
Badea MA, Balas M and Dinischiotu A. Biological properties and development of hypoxia in a breast cancer 3D model generated by hanging drop technique. (2021) Cell Biochem Biophys. Pubmed Cell Biochem Biophys
Chen YS, Chang HS, Hsiao HH, Chen YF, Kuo YP, Yen FL and Yen CH. Identification of Root Extract as a Liver Cancer Cell-Normal Keratinocyte Dual-Selective NRF2 Regulator. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article
Du J, Carroll RS, Steers GJ, Wagner BA, O'Leary BR, Jensen CS, Buettner GR and Cullen JJ. Catalase Modulates the Radio-Sensitization of Pancreatic Cancer Cells by Pharmacological Ascorbate. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article
Estaras M, Gonzalez-Portillo MR, Martinez R, Garcia A, Estevez M, Fernandez-Bermejo M, Mateos JM, Vara D, Blanco-Fernández G, Lopez-Guerra D, Roncero V, Salido GM and Gonzalez A. Melatonin Modulates the Antioxidant Defenses and the Expression of Proinflammatory Mediators in Pancreatic Stellate Cells Subjected to Hypoxia. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article
Sulaimon LA, Adisa RA, Samuel TA, Joel IY, Ayankojo AG, Abdulkareem FB and Olaniyi TO. Molecular mechanism of mitoquinol mesylate in mitigating the progression of hepatocellular carcinoma-in silico and in vivo studies. (2021) J Cell Biochem. Pubmed J Cell Biochem
Zhao F, Hong X, Li D, Wei Z, Ci X and Zhang S. Diosmetin induces apoptosis in ovarian cancer cells by activating reactive oxygen species and inhibiting the Nrf2 pathway. (2021) Med Oncol. 38, 54 Pubmed Med Oncol
Kreß JKC, Jessen C, Marquardt A, Hufnagel A and Meierjohann S. NRF2 Enables EGFR Signaling in Melanoma Cells. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci PMC Article
Abo El-Magd NF, El-Mesery M, El-Karef A and El-Shishtawy MM. Amelioration effect of black seed oil against high-fat diet-induced obesity in rats through Nrf2/HO-1 pathway. (2021) J Food Biochem. 45, e13693 Pubmed J Food Biochem
Jovanović M, Tenji D, Nikolić B, Srdić-Rajić T, Svirčev E and Mitić-Ćulafić D. In Vitro Study of Two Edible Polygonoideae Plants: Phenolic Profile, Cytotoxicity, and Modulation of Keap1-Nrf2 Gene Expression. (2021) Foods. 10, Pubmed Foods PMC Article
AboYoussef AM, Khalaf MM, Malak MN and Hamzawy MA. Repurposing of sildenafil as antitumour; induction of cyclic guanosine monophosphate/protein kinase G pathway, caspase-dependent apoptosis and pivotal reduction of Nuclear factor kappa light chain enhancer of activated B cells in lung cancer. (2021) J Pharm Pharmacol. Pubmed J Pharm Pharmacol
Yang S, Huang XL, Chen J, Mao LN, Liu X, Yuan WS, Wu XJ and Luo GW. Curcumin protects BEAS‑2B cells from PM‑induced oxidative stress and inflammation by activating NRF2/antioxidant response element pathways. (2021) Int J Mol Med. 47, Pubmed Int J Mol Med PMC Article
Prochownik EV. Reconciling the Biological and Transcriptional Variability of Hepatoblastoma with Its Mutational Uniformity. (2021) Cancers (Basel). 13, Pubmed Cancers (Basel)
Xu C, Mao L, Tian H, Lin S, Zhao X, Lin J, Li D, Li X and Mei X. MICAL1 (molecule interacting with CasL 1) protects oligodendrocyte cells from oxidative injury through regulating apoptosis, autophagy in spinal cord injury. (2021) Neurosci Lett. 750, 135712 Pubmed Neurosci Lett
Calabrese EJ, Kozumbo WJ, Kapoor R, Dhawan G, Jimenez PCL and Giordano J. NRF2 activation putatively mediates clinical benefits of low-dose radiotherapy in COVID-19 pneumonia and acute respiratory distress syndrome (ards): novel mechanistic considerations. (2021) Radiother Oncol. Pubmed Radiother Oncol PMC Article
Bellanti F and Vendemiale G. The Aging Liver: Redox Biology and Liver Regeneration. (2021) Antioxid Redox Signal. Pubmed Antioxid Redox Signal
Bian S, Zhao Y, Li F, Lu S, Yang S, Liu M, Wang S, Zhao D, Zhang W and Wang J. Knockdown of p62/sequestosome enhances ginsenoside Rh2-induced apoptosis in cervical cancer HeLa cells with no effect on autophagy. (2021) Biosci Biotechnol Biochem. 85, 1097-1103 Pubmed Biosci Biotechnol Biochem
Bateman NW, Tarney CM, Abulez T, Soltis AR, Zhou M, Conrads K, Litzi T, Oliver J, Hood B, Driggers P, Viollet C, Dalgard C, Wilkerson M, Catherino W, Hamilton CA, Darcy KM, Casablanca Y, Al-Hendy A, Segars J, Conrads TP and Larry Maxwell G. Proteogenomic landscape of uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer patients. (2021) Sci Rep. 11, 9371 Pubmed Sci Rep PMC Article
Guerrero-Rubio MA, Hernández-García S, García-Carmona F and Gandía-Herrero F. Flavonoids' Effects on Longevity, Fat Accumulation, Stress Resistance and Gene Modulation Involve mTOR, SKN-1 and DAF-16. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article
Alzahrani AM, Rajendran P, Veeraraghavan VP and Hanieh H. Cardiac Protective Effect of Kirenol against Doxorubicin-Induced Cardiac Hypertrophy in H9c2 Cells through Nrf2 Signaling via PI3K/AKT Pathways. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci PMC Article
Schirrmacher V. Less Can Be More: The Hormesis Theory of Stress Adaptation in the Global Biosphere and Its Implications. (2021) Biomedicines. 9, Pubmed Biomedicines PMC Article
Yang C, Zhang Y, Lin S, Liu Y and Li W. Suppressing the KIF20A/NUAK1/Nrf2/GPX4 signaling pathway induces ferroptosis and enhances the sensitivity of colorectal cancer to oxaliplatin. (2021) Aging (Albany NY). 13, Pubmed Aging (Albany NY)
Sun XH, Zhang H, Fan XP and Wang ZH. Astilbin Protects Against Carbon Tetrachloride-Induced Liver Fibrosis in Rats. (2021) Pharmacology. 1-9 Pubmed Pharmacology
Ibrahim Al-Obaide MA, Arutla V, Bacolod MD, Wang W, Zhang R and Srivenugopal KS. Genomic Space of in Human Glioma Revisited: Novel Motifs, Regulatory RNAs, NRF1, 2, and CTCF Involvement in Gene Expression. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci PMC Article
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