Which NRF2 Products Have Peer Reviewed Studies

English: Graph of Nrf2 publications (pubmed search) by year (Photo credit: Wikipedia)

There are currently over 2300 articles (peer reviewed clinical reviews and studies) on Pubmed.gov on the topic of NRF2 Activation. There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to Pubmed.gov and type in the name of their product. Pubmed is a website operated by the National Institute of Health (NIH). PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources. Last 200 NRF-2 Studies published on Pubmed

Thai SF, Jones CP, Robinette BL, Ren H, Vallanat B, Fisher AA and Kitchin KT. Effects of Silver Nanoparticles and Silver Nitrate on mRNA and microRNA Expression in Human Hepatocellular Carcinoma Cells (HepG2). (2021) J Nanosci Nanotechnol. 21, 5414-5428 Pubmed J Nanosci Nanotechnol

Thai SF, Jones CP, Robinette BL, Ren H, Vallant B, Fisher A and Kitchin KT. Effects of Copper Nanoparticles on mRNA and Small RNA Expression in Human Hepatocellular Carcinoma (HepG2) Cells. (2021) J Nanosci Nanotechnol. 21, 5083-5098 Pubmed J Nanosci Nanotechnol

Ayoup MS, Abu-Serie MM, Abdel-Hamid H and Teleb M. Beyond direct Nrf2 activation; reinvestigating 1,2,4-oxadiazole scaffold as a master key unlocking the antioxidant cellular machinery for cancer therapy. (2021) Eur J Med Chem. 220, 113475 Pubmed Eur J Med Chem

Osman AT, Sharkawi SMZ, Hassan MIA, Abo-Youssef AM and Hemeida RAM. Empagliflozin and neohesperidin mitigate methotrexate hepatotoxicity via Nrf2/PPARγ/HO-1 signalling initiation and suppression of NF-κB/Keap1/HSP70/caspase-3 axis in rats. (2021) Life Sci. 278, 119638 Pubmed Life Sci

Cao H, Zhang L, Qu Z, Tian S, Wang Z, Jiang Y, Hou Q, Jia L and Wang W. The protective effect of hydroxylated fullerene pretreatment on pilocarpine-induced status epilepticus. (2021) Brain Res. 1764, 147468 Pubmed Brain Res

Ooi BK, Phang SW, Yong PVC, Chellappan DK, Dua K, Khaw KY, Goh BH, Pusparajah P and Yap WH. In vitro evaluation of the involvement of Nrf2 in maslinic acid-mediated anti-inflammatory effects in atheroma pathogenesis. (2021) Life Sci. 278, 119658 Pubmed Life Sci

Zhang L, Gao X, Qin Z, Shi X, Xu K, Wang S, Tang M, Wang W, Gao S, Zuo L, Zhang L and Zhang W. USP15 participates in DBP-induced testicular oxidative stress injury through regulating the Keap1/Nrf2 signaling pathway. (2021) Sci Total Environ. 783, 146898 Pubmed Sci Total Environ

Tang Z, Ju Y, Dai X, Ni N, Liu Y, Zhang D, Gao H, Sun H, Zhang J and Gu P. HO-1-mediated ferroptosis as a target for protection against retinal pigment epithelium degeneration. (2021) Redox Biol. 43, 101971 Pubmed Redox Biol PMC Article

Kulkarni N, Gadde R, Gugnani KS, Vu N, Yoo C, Zaveri R and Betharia S. Neuroprotective effects of disubstituted dithiolethione ACDT against manganese-induced toxicity in SH-SY5Y cells. (2021) Neurochem Int. 147, 105052 Pubmed Neurochem Int

Gunaydin Akyildiz A, Boran T, Jannuzzi AT and Alpertunga B. Mitochondrial dynamics imbalance and mitochondrial dysfunction contribute to the molecular cardiotoxic effects of lenvatinib. (2021) Toxicol Appl Pharmacol. 423, 115577 Pubmed Toxicol Appl Pharmacol

Su Y, Wang Y, Liu M and Chen H. Hydrogen sulfide attenuates renal I/R‑induced activation of the inflammatory response and apoptosis via regulating Nrf2‑mediated NLRP3 signaling pathway inhibition. (2021) Mol Med Rep. 24, Pubmed Mol Med Rep PMC Article

Ahmed SA and Mohammed WI. Carvedilol induces the antiapoptotic proteins Nrf and Bcl and inhibits cellular apoptosis in aluminum-induced testicular toxicity in male Wistar rats. (2021) Biomed Pharmacother. 139, 111594 Pubmed Biomed Pharmacother

Ayıkgöz Y, Salih Aydın M, Kankılıç N and Temiz E. Nuclear factor erythroid 2-related factor 2 (Nrf2), tumor necrosis factor alpha protein (TNF-α), heme oxygenase-1 (HO-1) gene expressions during cardiopulmonary bypass. (2021) Gene. 790, 145690 Pubmed Gene

Liu P, Li J, Liu M, Zhang M, Xue Y, Zhang Y, Han X, Jing X and Chu L. Hesperetin modulates the Sirt1/Nrf2 signaling pathway in counteracting myocardial ischemia through suppression of oxidative stress, inflammation, and apoptosis. (2021) Biomed Pharmacother. 139, 111552 Pubmed Biomed Pharmacother

Hwang SH, Yang Y, Woo SH, Jung JH, Seo D, Kim DY and Kim Y. Thyroglobulin as a negative marker for malignancy in canine and human breast tumors. (2021) Mol Carcinog. 60, 455-468 Pubmed Mol Carcinog

Jia L, Hao H, Wang C and Wei J. Etomidate attenuates hyperoxia-induced acute lung injury in mice by modulating the Nrf2/HO-1 signaling pathway. (2021) Exp Ther Med. 22, 785 Pubmed Exp Ther Med PMC Article

Sriramajayam K, Peng D, Lu H, Zhou S, Bhat N, McDonald OG, Que J, Zaika A and El-Rifai W. Activation of NRF2 by APE1/REF1 is redox-dependent in Barrett's related esophageal adenocarcinoma cells. (2021) Redox Biol. 43, 101970 Pubmed Redox Biol PMC Article

Yin QH, Zhou Y and Li ZHY. Suppresses Cell Proliferation and Apoptosis via Regulation of SIRT1/PGC-1α/NRF2 Axis in Pancreatic Cancer. (2021) Cell J. 23, 199-210 Pubmed Cell J PMC Article

Chen M, Wang Z, Zhou W, Lu C, Ji T, Yang W, Jin Z, Tian Y, Lei W, Wu S, Fu Q, Wu Z, Wu X, Han M, Fang M and Yang Y. SIRT1/PGC-1α signaling activation by mangiferin attenuates cerebral hypoxia/reoxygenation injury in neuroblastoma cells. (2021) Eur J Pharmacol. 174236 Pubmed Eur J Pharmacol

Li X, Mu J, Lin Y, Zhao J and Meng X. Combination of cyanidin-3-O-glucoside and cisplatin induces oxidative stress and apoptosis in HeLa cells by reducing activity of endogenous antioxidants, increasing bax/bcl-2 mRNA expression ratio, and downregulating Nrf2 expression. (2021) J Food Biochem. e13806 Pubmed J Food Biochem

Zhao F, Hong X, Li D, Wei Z, Ci X and Zhang S. Correction to: Diosmetin induces apoptosis in ovarian cancer cells by activating reactive oxygen species and inhibiting the Nrf2 pathway. (2021) Med Oncol. 38, 78 Pubmed Med Oncol

Liu Y, Chen J, Xia P, Stratakis CA and Cheng Z. Loss of PKA regulatory subunit 1α aggravates cardiomyocyte necrosis and myocardial ischemia/reperfusion injury. (2021) J Biol Chem. 100850 Pubmed J Biol Chem

Cheng C, Yuan F, Chen XP, Zhang W, Zhao XL, Jiang ZP, Zhou HH, Zhou G and Cao S. Inhibition of Nrf2-mediated glucose metabolism by brusatol synergistically sensitizes acute myeloid leukemia to Ara-C. (2021) Biomed Pharmacother. 111652 Pubmed Biomed Pharmacother

Augusti PR, Conterato GMM, Denardin CC, Prazeres ID, Serra AT, Bronze MR and Emanuelli T. BIOACTIVITY, BIOAVAILABILITY, AND GUT MICROBIOTA TRANSFORMATIONS OF DIETARY PHENOLIC COMPOUNDS: IMPLICATIONS FOR COVID-19. (2021) J Nutr Biochem. 108787 Pubmed J Nutr Biochem PMC Article

Fu D, Wang C, Yu L and Yu R. Induction of ferroptosis by ATF3 elevation alleviates cisplatin resistance in gastric cancer by restraining Nrf2/Keap1/xCT signaling. (2021) Cell Mol Biol Lett. 26, 26 Pubmed Cell Mol Biol Lett PMC Article

Liao Y, Jia X, Ren Y, Deji Z, Gesang Y, Ning N, Feng H, Yu H and Wei A. Suppressive role of microRNA-130b-3p in ferroptosis in melanoma cells correlates with DKK1 inhibition and Nrf2-HO-1 pathway activation. (2021) Hum Cell. Pubmed Hum Cell

Chen Z, Zhang H, Zhou J, Stone C, Ding Y, Zhang Y, Ren C, Yin X and Meng R. CORM-2 inhibits intracerebral hemorrhage-mediated inflammation. (2021) Neurol Res. 1-8 Pubmed Neurol Res

Fakhri S, Tomas M, Capanoglu E, Hussain Y, Abbaszadeh F, Lu B, Hu X, Wu J, Zou L, Smeriglio A, Simal-Gandara J, Cao H, Xiao J and Khan H. Antioxidant and anticancer potentials of edible flowers: where do we stand?. (2021) Crit Rev Food Sci Nutr. 1-57 Pubmed Crit Rev Food Sci Nutr

Ghosh S, Dutta N, Banerjee P, Gajbhiye RL, Sareng HR, Kapse P, Pal S, Burdelya L, Mandal NC, Ravichandiran V, Bhattacharjee A, Kundu GC, Gudkov AV and Pal M. Induction of monoamine oxidase A-mediated oxidative stress and impairment of NRF2-antioxidant defence response by polyphenol-rich fraction of Bergenia ligulata sensitizes prostate cancer cells in vitro and in vivo. (2021) Free Radic Biol Med. Pubmed Free Radic Biol Med

Truong VL, Manochai B, Pham TT and Jeong WS. Antioxidant and Anti-inflammatory Activities of Oil in HepG2 Cells and Lipopolysaccharide-Stimulated RAW 264.7 Macrophages. (2021) J Med Food. Pubmed J Med Food

Suh KS, Chon S, Jung WW and Choi EM. Protective effects of sciadopitysin against methylglyoxal-induced degeneration in neuronal SK-N-MC cells. (2021) J Appl Toxicol. Pubmed J Appl Toxicol

Xu X, Zhang X, Zhang Y, Yang L, Liu Y, Huang S, Lu L, Kong L, Li Z, Guo Q and Zhao L. Author Correction: Wogonin reversed resistant human myelogenous leukemia cells via inhibiting Nrf2 signaling by Stat3/ NF-κB inactivation. (2021) Sci Rep. 11, 12746 Pubmed Sci Rep

Sivinski J, Zhang DD and Chapman E. Targeting NRF2 to treat cancer. (2021) Semin Cancer Biol. Pubmed Semin Cancer Biol

Cai J, Yi M, Tan Y, Li X, Li G, Zeng Z, Xiong W and Xiang B. Natural product triptolide induces GSDME-mediated pyroptosis in head and neck cancer through suppressing mitochondrial hexokinase-ΙΙ. (2021) J Exp Clin Cancer Res. 40, 190 Pubmed J Exp Clin Cancer Res PMC Article

Wang S, Cao K, Liao Y, Zhang W, Zheng J, Li X, Huang M, Zhong Y, Hu X, Chen and Wang Y. CDCA2 protects against oxidative stress by promoting BRCA1-NRF2 signaling in hepatocellular carcinoma. (2021) Oncogene. Pubmed Oncogene

Qin S, He X, Lin H, Schulte BA, Zhao M, Tew KD and Wang GY. Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair. (2021) Free Radic Biol Med. 169, 238-247 Pubmed Free Radic Biol Med PMC Article

Dai Y, Li F, Jiao Y, Wang G, Zhan T, Xia Y, Liu H, Yang H, Zhang J and Tang L. Mortalin/glucose-regulated protein 75 promotes the cisplatin-resistance of gastric cancer via regulating anti-oxidation/apoptosis and metabolic reprogramming. (2021) Cell Death Discov. 7, 140 Pubmed Cell Death Discov

Kabel AM, Ashour AM, Ali DA and Arab HH. The immunomodulatory effects of topiramate on azoxymethane-induced colon carcinogenesis in rats: The role of the inflammatory cascade, vascular endothelial growth factor, AKT/mTOR/MAP kinase signaling and the apoptotic markers. (2021) Int Immunopharmacol. 98, 107830 Pubmed Int Immunopharmacol

Li X, Zhou L, Zhang Y, He X, Lu H, Zhang L, Tian Y, Liu X, Zheng H, Shao J and Long M. mGPDH Deficiency leads to melanoma metastasis via induced NRF2. (2021) J Cell Mol Med. 25, 5305-5315 Pubmed J Cell Mol Med

Li KW, Liang YY, Wang Q, Li Y, Zhou SJ, Wei HC, Zhou CZ and Wan XH. Brucea javanica: A review on anticancer of its pharmacological properties and clinical researches. (2021) Phytomedicine. 86, 153560 Pubmed Phytomedicine

Oh S, Tsujimoto T, Kim B, Uchida F, Suzuki H, Iizumi S, Isobe T, Sakae T, Tanaka K and Shoda J. Weight-loss-independent benefits of exercise on liver steatosis and stiffness in Japanese men with NAFLD. (2021) JHEP Rep. 3, 100253 Pubmed JHEP Rep PMC Article

Poznanski SM, Singh K, Ritchie TM, Aguiar JA, Fan IY, Portillo AL, Rojas EA, Vahedi F, El-Sayes A, Xing S, Butcher M, Lu Y, Doxey AC, Schertzer JD, Hirte HW and Ashkar AA. Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment. (2021) Cell Metab. 33, 1205-1220.e5 Pubmed Cell Metab

Yaqub F, Latief N, Butt H, Naseer N and Riazuddin S. Alpha lipoic acid priming enhances the hepatoprotective effect of adipose derived stem cells in CCl4 induced hepatic injury in-vitro. (2021) Eur J Pharmacol. 174201 Pubmed Eur J Pharmacol

Hu J, Wang J, Li C and Shang Y. Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway. (2021) J Cell Mol Med. 25, 5001-5014 Pubmed J Cell Mol Med

Yoshida GJ and Saya H. Molecular pathology underlying the robustness of cancer stem cells. (2021) Regen Ther. 17, 38-50 Pubmed Regen Ther PMC Article

Liu M, Zheng B, Liu P, Zhang J, Chu X, Dong C, Shi J, Liang Y, Chu L, Liu Y and Han X. Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury. (2021) Mol Med Rep. 23, Pubmed Mol Med Rep PMC Article

Shan HJ, Zhu LQ, Yao C, Zhang ZQ, Liu YY, Jiang Q, Zhou XZ, Wang XD and Cao C. MAFG-driven osteosarcoma cell progression is inhibited by a novel miRNA miR-4660. (2021) Mol Ther Nucleic Acids. 24, 385-402 Pubmed Mol Ther Nucleic Acids PMC Article

Yue CF, Li LS, Ai L, Deng JK and Guo YM. Corrigendum to "sMicroRNA-28-5p acts as a metastasis suppressor in gastric cancer by targeting Nrf2". (2021) Exp Cell Res. 403, 112616 Pubmed Exp Cell Res

Akagi R, Kubo T, Hatori Y, Miyamoto T and Inouye S. Heme oxygenase-1 induction by heat shock in rat hepatoma cell line is regulated by the coordinated function of HSF1, NRF2, AND BACH1. (2021) J Biochem. Pubmed J Biochem

Haque E, Śmiech M, Łuczyńska K, Bouchard MF, Viger R, Kono H, Pierzchała M and Taniguchi H. NRF2 DLG Domain Mutations Identified in Japanese Liver Cancer Patients Affect the Transcriptional Activity in HCC Cell Lines. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci PMC Article

Fusco R, Salinaro AT, Siracusa R, D'Amico R, Impellizzeri D, Scuto M, Ontario ML, Crea R, Cordaro M, Cuzzocrea S, Di Paola R and Calabrese V. Hidrox Counteracts Cyclophosphamide-Induced Male Infertility through NRF2 Pathways in a Mouse Model. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Chen J, Chen Y, Zheng Y, Zhao J, Yu H, Zhu J and Li D. Neuroprotective Effects and Mechanisms of Procyanidins In Vitro and In Vivo. (2021) Molecules. 26, Pubmed Molecules PMC Article

Schmidlin CJ, Shakya A, Dodson M, Chapman E and Zhang DD. The intricacies of NRF2 regulation in cancer. (2021) Semin Cancer Biol. Pubmed Semin Cancer Biol

Wijaya LS, Rau C, Braun TS, Marangoz S, Spegg V, Vlasveld M, Albrecht W, Brecklinghaus T, Kamp H, Beltman JB, Hengstler JG, van de Water B, Leist M and Schildknecht S. Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes. (2021) Cell Biol Toxicol. Pubmed Cell Biol Toxicol

Yoon SJ, Kim SK, Lee NY, Choi YR, Kim HS, Gupta H, Youn GS, Sung H, Shin MJ and Suk KT. Effect of Korean Red Ginseng on metabolic syndrome. (2021) J Ginseng Res. 45, 380-389 Pubmed J Ginseng Res PMC Article

Yu H, Gao HY, Guo H, Wang GZ, Yang YQ, Hu Q, Liang LJ, Zhao Q, Xie DW, Rao Y and Zhou GB. Upregulation of wild-type p53 by small molecule-induced elevation of NQO1 in non-small cell lung cancer cells. (2021) Acta Pharmacol Sin. Pubmed Acta Pharmacol Sin

Bohn T, Bonet ML, Borel P, Keijer J, Landrier JF, Milisav I, Ribot J, Riso P, Winklhofer-Roob B, Sharoni Y, Corte-Real J, van Helden Y, Loizzo MR, Poljšak B, Porrini M, Roob J, Trebše P, Tundis R, Wawrzyniak A, Rühl R and Dulińska-Litewka J. Mechanistic Aspects of Carotenoid Health Benefits - Where are we Now?. (2021) Nutr Res Rev. 1-66 Pubmed Nutr Res Rev

Mikac S, Rychłowski M, Dziadosz A, Szabelska-Beresewicz A, Fahraeus R, Hupp T and Sznarkowska A. Identification of a Stable, Non-Canonically Regulated Nrf2 Form in Lung Cancer Cells. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Wilson CJ, Chang M, Karttunen M and Choy WY. KEAP1 Cancer Mutants: A Large-Scale Molecular Dynamics Study of Protein Stability. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci PMC Article

Kim M, Jee SC, Kim KS, Kim HS, Yu KN and Sung JS. Quercetin and Isorhamnetin Attenuate Benzo[a]pyrene-Induced Toxicity by Modulating Detoxification Enzymes through the AhR and NRF2 Signaling Pathways. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Lee DY, Song MY and Kim EH. Role of Oxidative Stress and Nrf2/KEAP1 Signaling in Colorectal Cancer: Mechanisms and Therapeutic Perspectives with Phytochemicals. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

El Badawy SA, Ogaly HA, Abd-Elsalam RM and Azouz AA. Benzyl isothiocyanates modulate inflammation, oxidative stress, and apoptosis Nrf2/HO-1 and NF-κB signaling pathways on indomethacin-induced gastric injury in rats. (2021) Food Funct. Pubmed Food Funct

Long X, Sun F, Wang Z, Liu T, Gong J, Kan X, Zou Y and Zhao X. CQPC08 protects rats from lead-induced oxidative damage by regulating the Keap1/Nrf2/ARE pathway. (2021) Food Funct. Pubmed Food Funct

Zedan AMG, Sakran MI, Bahattab O, Hawsawi YM, Al-Amer O, Oyouni AAA, Nasr Eldeen SK and El-Magd MA. Oriental Hornet () Larval Extracts Induce Antiproliferative, Antioxidant, Anti-Inflammatory, and Anti-Migratory Effects on MCF7 Cells. (2021) Molecules. 26, Pubmed Molecules

Gao Y, Yuan D, Gai L, Wu X, Shi Y, He Y, Liu C, Zhang C, Zhou G and Yuan C. Saponins from ameliorate age-related renal fibrosis by inhibition of inflammation mediated by NF-κB and TGF-β1/Smad signaling and suppression of oxidative stress via activation of Nrf2-ARE signaling. (2021) J Ginseng Res. 45, 408-419 Pubmed J Ginseng Res PMC Article

Tsai CS, Lin FY, Liu YC, Lin YW, Tsai YT, Huang CY, Lin SJ, Li CY, Lin CY, Tseng HT and Shih CM. Transferring Plasmon Effect on a Biological System: Expression of Biological Polymers in Chronic Rejection and Inflammatory Rat Model. (2021) Polymers (Basel). 13, Pubmed Polymers (Basel)

Mohammadi H and Ashari S. Mechanistic insight into toxicity of phthalates, the involved receptors, and the role of Nrf2, NF-κB, and PI3K/AKT signaling pathways. (2021) Environ Sci Pollut Res Int. Pubmed Environ Sci Pollut Res Int

Xie H, Chun FK, Rutz J and Blaheta RA. Sulforaphane Impact on Reactive Oxygen Species (ROS) in Bladder Carcinoma. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci

Zhu J, Wang H, Sun Q, Ji X, Zhu L, Cong Z, Zhou Y, Liu H and Zhou M. Correction to: Nrf2 is required to maintain the self-renewal of glioma stem cells. (2021) BMC Cancer. 21, 582 Pubmed BMC Cancer PMC Article

Sugimoto M, Ko R, Goshima H, Koike A, Shibano M and Fujimori K. Formononetin attenuates HO-induced cell death through decreasing ROS level by PI3K/Akt-Nrf2-activated antioxidant gene expression and suppressing MAPK-regulated apoptosis in neuronal SH-SY5Y cells. (2021) Neurotoxicology. 85, 186-200 Pubmed Neurotoxicology

Yu X, Mansouri A, Liu Z, Gao R, Li K, Chen C, Huang Y, Chen Z, Chen S, Lu Y, Li Y, Zeng C and Zeng Y. NRF2 activation induced by PML-RARα promotes microRNA 125b-1 expression and confers resistance to chemotherapy in acute promyelocytic leukemia. (2021) Clin Transl Med. 11, e418 Pubmed Clin Transl Med PMC Article

Nitti M, Ivaldo C, Traverso N and Furfaro AL. Clinical Significance of Heme Oxygenase 1 in Tumor Progression. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Kamai T, Higashi S, Murakami S, Arai K, Namatame T, Kijima T, Abe H, Jamiyan T, Ishida K, Shirataki H and Yoshida KI. Single nucleotide variants of succinate dehydrogenase A (SDHA) gene in renal cell carcinoma. (2021) Cancer Sci. Pubmed Cancer Sci

Šuran J, Cepanec I, Mašek T, Radić B, Radić S, Tlak Gajger I and Vlainić J. Propolis Extract and Its Bioactive Compounds-From Traditional to Modern Extraction Technologies. (2021) Molecules. 26, Pubmed Molecules PMC Article

Wu Y, Chen H, Zou Y, Yi R, Mu J and Zhao X. Lactobacillus plantarum HFY09 alleviates alcohol-induced gastric ulcers in mice via an anti-oxidative mechanism. (2021) J Food Biochem. 45, e13726 Pubmed J Food Biochem

Fakhri S, Nouri Z, Moradi SZ, Akkol EK, Piri S, Sobarzo-Sánchez E, Farzaei MH and Echeverría J. Targeting Multiple Signal Transduction Pathways of SARS-CoV-2: Approaches to COVID-19 Therapeutic Candidates. (2021) Molecules. 26, Pubmed Molecules PMC Article

Ebrahimpour A, Wang M, Li L, Jegga AG, Bonnen MD, Eissa NT, Raghu G, Jyothula S, Kheradmand F, Hanania NA, Rosas IO and Ghebre YT. Esomeprazole attenuates inflammatory and fibrotic response in lung cells through the MAPK/Nrf2/HO1 pathway. (2021) J Inflamm (Lond). 18, 17 Pubmed J Inflamm (Lond) PMC Article

Meier JK, Schnetz M, Beck S, Schmid T, Dominguez M, Kalinovic S, Daiber A, Brüne B and Jung M. Iron-Bound Lipocalin-2 Protects Renal Cell Carcinoma from Ferroptosis. (2021) Metabolites. 11, Pubmed Metabolites PMC Article

Ishak NIM, Mohamed S, Madzuki IN, Mustapha NM and Esa NM. Limonin modulated immune and inflammatory responses to suppress colorectal adenocarcinoma in mice model. (2021) Naunyn Schmiedebergs Arch Pharmacol. Pubmed Naunyn Schmiedebergs Arch Pharmacol

Bolland H, Ma TS, Ramlee S, Ramadan K and Hammond EM. Links between the unfolded protein response and the DNA damage response in hypoxia: a systematic review. (2021) Biochem Soc Trans. Pubmed Biochem Soc Trans

Grewal AK, Singh TG, Sharma D, Sharma V, Singh M, Rahman MH, Najda A, Walasek-Janusz M, Kamel M, Albadrani GM, Akhtar MF, Saleem A and Abdel-Daim MM. Mechanistic insights and perspectives involved in neuroprotective action of quercetin. (2021) Biomed Pharmacother. 140, 111729 Pubmed Biomed Pharmacother

Farkhondeh T, Pourbagher-Shahri AM, Azimi-Nezhad M, Forouzanfar F, Brockmueller A, Ashrafizadeh M, Talebi M, Shakibaei M and Samarghandian S. Roles of Nrf2 in Gastric Cancer: Targeting for Therapeutic Strategies. (2021) Molecules. 26, Pubmed Molecules

Hassanein EHM, Mohamed WR, Khalaf MM, Shalkami AS, Sayed AM and Hemeida RAM. Diallyl disulfide ameliorates methotrexate-induced nephropathy in rats: Molecular studies and network pharmacology analysis. (2021) J Food Biochem. e13765 Pubmed J Food Biochem

Mondal G and Debnath J. NRF2 activates macropinocytosis upon autophagy inhibition. (2021) Cancer Cell. 39, 596-598 Pubmed Cancer Cell

Chen G, Yang Z, Wen D, Guo J, Xiong Q, Li P, Zhao L, Wang J, Wu C and Dong L. Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis. (2021) Immun Inflamm Dis. Pubmed Immun Inflamm Dis

Li J, Jiang H, Wu P, Li S, Han B, Yang Q, Wang X, Han B, Deng N, Qu B and Zhang Z. Toxicological effects of deltamethrin on quail cerebrum: Weakened antioxidant defense and enhanced apoptosis. (2021) Environ Pollut. 286, 117319 Pubmed Environ Pollut

Levings DC, Lacher SE, Palacios-Moreno J and Slattery M. Transcriptional reprogramming by oxidative stress occurs within a predefined chromatin accessibility landscape. (2021) Free Radic Biol Med. 171, 319-331 Pubmed Free Radic Biol Med

Jiang C, Li R, Xiu C, Ma X, Hu H, Wei L, Tang Y, Tao M and Zhao J. Upregulating CXCR7 accelerates endothelial progenitor cell-mediated endothelial repair by activating Akt/Keap-1/Nrf2 signaling in diabetes mellitus. (2021) Stem Cell Res Ther. 12, 264 Pubmed Stem Cell Res Ther PMC Article

Peng YJ, Lu JW, Lee CH, Lee HS, Chu YH, Ho YJ, Liu FC, Huang CJ, Wu CC and Wang CC. Cardamonin Attenuates Inflammation and Oxidative Stress in Interleukin-1β-Stimulated Osteoarthritis Chondrocyte through the Nrf2 Pathway. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel)

Lu Z, Ren Y, Yang L, Jia A, Hu Y, Zhao Y, Zhao W, Yu B, Zhao W, Zhang J and Hou G. Inhibiting autophagy enhances sulforaphane-induced apoptosis targeting NRF2 in esophageal squamous cell carcinoma. (2021) Acta Pharm Sin B. 11, 1246-1260 Pubmed Acta Pharm Sin B PMC Article

Su H, Yang F, Sun B and Karin M. Macropinocytosis: the big drinker behind cancer cell self-consumption. (2021) Autophagy. 17, 1290-1291 Pubmed Autophagy PMC Article

Li J, Wang T, Liu P, Yang F, Wang X, Zheng W and Sun W. Hesperetin ameliorates hepatic oxidative stress and inflammation the PI3K/AKT-Nrf2-ARE pathway in oleic acid-induced HepG2 cells and a rat model of high-fat diet-induced NAFLD. (2021) Food Funct. 12, 3898-3918 Pubmed Food Funct

Li XX, Yuan R, Wang QQ, Han S, Liu Z, Xu Q, Yang S and Gao H. Rotundic acid reduces LPS-induced acute lung injury in vitro and in vivo through regulating TLR4 dimer. (2021) Phytother Res. Pubmed Phytother Res

Dai M, Chen B, Wang X, Gao C and Yu H. Icariin enhance mild hypothermia-induced neuroprotection via inhibiting the activation of NF-κB in experimental ischemic stroke. (2021) Metab Brain Dis. Pubmed Metab Brain Dis

Ge MH, Tian H, Mao L, Li DY, Lin JQ, Hu HS, Huang SC, Zhang CJ and Mei XF. Zinc attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury by activating Nrf2/GPX4 defense pathway. (2021) CNS Neurosci Ther. Pubmed CNS Neurosci Ther

Calabrese EJ, Priest ND and Kozumbo WJ. Thresholds for carcinogens. (2021) Chem Biol Interact. 341, 109464 Pubmed Chem Biol Interact

Jin L and Tong L. PAQR3 inhibits proliferation and aggravates ferroptosis in acute lymphoblastic leukemia through modulation Nrf2 stability. (2021) Immun Inflamm Dis. Pubmed Immun Inflamm Dis

Ekuban FA, Zong C, Takikawa M, Morikawa K, Sakurai T, Ichihara S, Itoh K, Yamamoto M, Ohsako S and Ichihara G. Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. (2021) Toxicology. 456, 152785 Pubmed Toxicology

Abd El-Ghafar OAM, Hassanein EHM, Sayed AM, Rashwan EK, Shalkami AS and Mahmoud AM. Acetovanillone prevents cyclophosphamide-induced acute lung injury by modulating PI3K/Akt/mTOR and Nrf2 signaling in rats. (2021) Phytother Res. Pubmed Phytother Res

Han EJ, Fernando IPS, Kim HS, Lee DS, Kim A, Je JG, Seo MJ, Jee YH, Jeon YJ, Kim SY and Ahn G. (-)-Loliolide Isolated from Suppressed Oxidative Stress and Inflammation by Activating Nrf2/HO-1 Signaling in IFN-γ/TNF-α-Stimulated HaCaT Keratinocytes. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel)

Consonni FM, Bleve A, Totaro MG, Storto M, Kunderfranco P, Termanini A, Pasqualini F, Alì C, Pandolfo C, Sgambelluri F, Grazia G, Santinami M, Maurichi A, Milione M, Erreni M, Doni A, Fabbri M, Gribaldo L, Rulli E, Soares MP, Torri V, Mortarini R, Anichini A and Sica A. Heme catabolism by tumor-associated macrophages controls metastasis formation. (2021) Nat Immunol. 22, 595-606 Pubmed Nat Immunol

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