English: Graph of Nrf2 publications (pubmed se...

English: Graph of Nrf2 publications (pubmed search) by year (Photo credit: Wikipedia)

There are currently over 2300 articles (peer reviewed clinical reviews and studies) on Pubmed.gov on the topic of NRF2 Activation. There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to Pubmed.gov and type in the name of their product. Pubmed is a website operated by the National Institute of Health (NIH).  PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources. Last 200 NRF-2 Studies published on Pubmed
Senyuk V, Eskandari N, Jiang Y, Garcia-Varela R, Sundstrom R, Leanza L, Peruzzo R, Burkard M, Minshall RD and Gentile S. Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs. (2021) Redox Biol. 45, 102030 Pubmed Redox Biol PMC Article
Yaqub F, Latief N, Butt H, Naseer N and Riazuddin S. Alpha lipoic acid priming enhances the hepatoprotective effect of adipose derived stem cells in CCl4 induced hepatic injury in-vitro. (2021) Eur J Pharmacol. 906, 174201 Pubmed Eur J Pharmacol
Jiang P, Chen L, Xu J, Liu W, Feng F and Qu W. Neuroprotective Effects of Rhynchophylline Against Aβ-Induced Oxidative Stress, Neurodegeneration, and Memory Impairment Via Nrf2-ARE Activation. (2021) Neurochem Res. 46, 2439-2450 Pubmed Neurochem Res
Liu H, Zhu S, Han W, Cai Y and Liu C. DMEP induces mitochondrial damage regulated by inhibiting Nrf2 and SIRT1/PGC-1α signaling pathways in HepG2 cells. (2021) Ecotoxicol Environ Saf. 221, 112449 Pubmed Ecotoxicol Environ Saf
Liu HY, Zhang HS, Liu MY, Li HM, Wang XY and Wang M. GLS1 depletion inhibited colorectal cancer proliferation and migration via redox/Nrf2/autophagy-dependent pathway. (2021) Arch Biochem Biophys. 708, 108964 Pubmed Arch Biochem Biophys
Niu LT, Wang YQ, Wong CCL, Gao SX, Mo XD and Huang XJ. Targeting IFN-γ-inducible lysosomal thiol reductase overcomes chemoresistance in AML through regulating the ROS-mediated mitochondrial damage. (2021) Transl Oncol. 14, 101159 Pubmed Transl Oncol
Hong J, Shi Z, Li C, Ji X, Li S, Chen Y, Jiang G, Shi M, Wang W, Zhang Y, Hu B and Yan S. Virtual screening identified natural Keap1-Nrf2 PPI inhibitor alleviates inflammatory osteoporosis through Nrf2-mir214-Traf3 axis. (2021) Free Radic Biol Med. 171, 365-378 Pubmed Free Radic Biol Med
Mishra R, Nawas AF and Mendelson CR. Role of NRF2 in immune modulator expression in developing lung. (2021) FASEB J. 35, e21758 Pubmed FASEB J
Ooi BK, Phang SW, Yong PVC, Chellappan DK, Dua K, Khaw KY, Goh BH, Pusparajah P and Yap WH. In vitro evaluation of the involvement of Nrf2 in maslinic acid-mediated anti-inflammatory effects in atheroma pathogenesis. (2021) Life Sci. 278, 119658 Pubmed Life Sci
Wu S, Yu W, Jiang X, Huang R, Zhang X, Lan J, Zhong G, Wan F, Tang Z and Hu L. Protective effects of curcumin on ATO-induced nephrotoxicity in ducks in relation to suppressed autophagy, apoptosis and dyslipidemia by regulating oxidative stress. (2021) Ecotoxicol Environ Saf. 219, 112350 Pubmed Ecotoxicol Environ Saf
Osman AT, Sharkawi SMZ, Hassan MIA, Abo-Youssef AM and Hemeida RAM. Empagliflozin and neohesperidin mitigate methotrexate hepatotoxicity via Nrf2/PPARγ/HO-1 signalling initiation and suppression of NF-κB/Keap1/HSP70/caspase-3 axis in rats. (2021) Life Sci. 278, 119638 Pubmed Life Sci
Hseu YC, Vudhya Gowrisankar Y, Wang LW, Zhang YZ, Chen XZ, Huang PJ, Yen HR and Yang HL. The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated α-MSH in keratinocytes via Nrf2-mediated antioxidant pathways. (2021) Redox Biol. 44, 102007 Pubmed Redox Biol PMC Article
Zhang L, Gao X, Qin Z, Shi X, Xu K, Wang S, Tang M, Wang W, Gao S, Zuo L, Zhang L and Zhang W. USP15 participates in DBP-induced testicular oxidative stress injury through regulating the Keap1/Nrf2 signaling pathway. (2021) Sci Total Environ. 783, 146898 Pubmed Sci Total Environ
Grewal AK, Singh TG, Sharma D, Sharma V, Singh M, Rahman MH, Najda A, Walasek-Janusz M, Kamel M, Albadrani GM, Akhtar MF, Saleem A and Abdel-Daim MM. Mechanistic insights and perspectives involved in neuroprotective action of quercetin. (2021) Biomed Pharmacother. 140, 111729 Pubmed Biomed Pharmacother
Mardi A, Biglar A, Nejatbakhsh R and Abdanipour A. Valproic Acid Ameliorates Locomotor Function in the Rat Model of Contusion via Alteration of Mst1, Bcl-2, and Nrf2 Gene Expression. (2021) Iran Biomed J. 25, 303-7 Pubmed Iran Biomed J
El Badawy SA, Ogaly HA, Abd-Elsalam RM and Azouz AA. Benzyl isothiocyanates modulate inflammation, oxidative stress, and apoptosis via Nrf2/HO-1 and NF-κB signaling pathways on indomethacin-induced gastric injury in rats. (2021) Food Funct. 12, 6001-6013 Pubmed Food Funct
Long X, Sun F, Wang Z, Liu T, Gong J, Kan X, Zou Y and Zhao X. CQPC08 protects rats from lead-induced oxidative damage by regulating the Keap1/Nrf2/ARE pathway. (2021) Food Funct. 12, 6029-6044 Pubmed Food Funct
Gao L, Liu Y, Du X, Ma S, Ge M, Tang H, Han C, Zhao X, Liu Y, Shao Y, Wu Z, Zhang L, Meng F and Xiao-Feng Qin F. The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression. (2021) Cell Death Dis. 12, 680 Pubmed Cell Death Dis PMC Article
Cheng L, Wang H, Li S, Liu Z and Wang C. New insights into the mechanism of Keap1-Nrf2 interaction based on cancer-associated mutations. (2021) Life Sci. 119791 Pubmed Life Sci
Julián-Serrano S, Yuan F, Wheeler W, Benyamin B, Machiela MJ, Arslan AA, Beane-Freeman LE, Bracci PM, Duell EJ, Du M, Gallinger S, Giles GG, Goodman PJ, Kooperberg C, Marchand LL, Neale RE, Shu XO, Van Den Eeden SK, Visvanathan K, Zheng W, Albanes D, Andreotti G, Ardanaz E, Babic A, Berndt SI, Brais LK, Brennan P, Bueno-de-Mesquita B, Buring JE, Chanock SJ, Childs EJ, Chung CC, Fabiánová E, Foretová L, Fuchs CS, Gaziano JM, Gentiluomo M, Giovannucci EL, Goggins MG, Hackert T, Hartge P, Hassan MM, Holcátová I, Holly EA, Hung RI, Janout V, Kurtz RC, Lee IM, Malats N, McKean D, Milne RL, Newton CC, Oberg AL, Perdomo S, Peters U, Porta M, Rothman N, Schulze MB, Sesso HD, Silverman DT, Thompson IM, Wactawski-Wende J, Weiderpass E, Wenstzensen N, White E, Wilkens LR, Yu H, Zeleniuch-Jacquotte A, Zhong J, Kraft P, Li D, Campbell PT, Petersen GM, Wolpin BM, Risch HA, Amundadottir LT, Klein AP, Yu K and Stolzenberg-Solomon RZ. Hepcidin-regulating iron metabolism genes and pancreatic ductal adenocarcinoma: a pathway analysis of genome-wide association studies. (2021) Am J Clin Nutr. Pubmed Am J Clin Nutr
Gunaydin Akyildiz A, Boran T, Jannuzzi AT and Alpertunga B. Mitochondrial dynamics imbalance and mitochondrial dysfunction contribute to the molecular cardiotoxic effects of lenvatinib. (2021) Toxicol Appl Pharmacol. 423, 115577 Pubmed Toxicol Appl Pharmacol
Su Y, Wang Y, Liu M and Chen H. Hydrogen sulfide attenuates renal I/R‑induced activation of the inflammatory response and apoptosis via regulating Nrf2‑mediated NLRP3 signaling pathway inhibition. (2021) Mol Med Rep. 24, Pubmed Mol Med Rep PMC Article
Yang X, Wang X, Gao D, Zhang Y, Chen X, Xia Q, Jin M, Sun C, He Q, Wang R and Liu K. Developmental toxicity caused by sanguinarine in zebrafish embryos via regulating oxidative stress, apoptosis and wnt pathways. (2021) Toxicol Lett. 350, 71-80 Pubmed Toxicol Lett
Zhang N, Zhao W, Hu ZJ, Ge SM, Huo Y, Liu LX and Gao BL. Protective effects and mechanisms of high-dose vitamin C on sepsis-associated cognitive impairment in rats. (2021) Sci Rep. 11, 14511 Pubmed Sci Rep PMC Article
Fu J, Ni C, Ni HD, Xu LS, He QL, Pan H, Huang DD, Sun YB, Luo G, Liu MJ and Yao M. Spinal Nrf2 translocation may inhibit neuronal NF-κB activation and alleviate allodynia in a rat model of bone cancer pain. (2021) J Neurochem. Pubmed J Neurochem
Khan A, Park TJ, Ikram M, Ahmad S, Ahmad R, Jo MG and Kim MO. Antioxidative and Anti-inflammatory Effects of Kojic Acid in Aβ-Induced Mouse Model of Alzheimer's Disease. (2021) Mol Neurobiol. Pubmed Mol Neurobiol
Bashir DW, Rashad MM, Ahmed YH, Drweesh EA, Elzahany EAM, Abou-El-Sherbini KS and El-Leithy EMM. The ameliorative effect of nanoselenium on histopathological and biochemical alterations induced by melamine toxicity on the brain of adult male albino rats. (2021) Neurotoxicology. 86, 37-51 Pubmed Neurotoxicology
Amin N, Du X, Chen S, Ren Q, Hussien AB, Botchway BOA, Hu Z and Fang M. Evaluating the therapeutic impact of thymoquinone toward ischemic brain injury alleviation via Nrf2/HO-1 pathway. (2021) Expert Opin Ther Targets. Pubmed Expert Opin Ther Targets
Javadinia SA, Nazeminezhad N, Ghahramani-Asl R, Soroosh D, Fazilat-Panah D, PeyroShabany B, Saberhosseini SN, Mehrabian A, Taghizadeh-Hesary F, Nematshahi M, Dhawan G, Welsh JS, Calabrese EJ and Kapoor R. Low-Dose Radiation Therapy for Osteoarthritis and Enthesopathies: A Review of Current Data. (2021) Int J Radiat Biol. 1-60 Pubmed Int J Radiat Biol
Hwang SH, Yang Y, Woo SH, Jung JH, Seo D, Kim DY and Kim Y. Thyroglobulin as a negative marker for malignancy in canine and human breast tumors. (2021) Mol Carcinog. 60, 455-468 Pubmed Mol Carcinog
Dai B, Augustine JJ, Kang Y, Roife D, Li X, Deng J, Tan L, Rusling LA, Weinstein JN, Lorenzi PL, Kim MP and Fleming JB. Compound NSC84167 selectively targets NRF2-activated pancreatic cancer by inhibiting asparagine synthesis pathway. (2021) Cell Death Dis. 12, 693 Pubmed Cell Death Dis PMC Article
Hou K, Shen J, Yan J, Zhai C, Zhang J, Pan JA, Zhang Y, Jiang Y, Wang Y, Lin RZ, Cong H, Gao S and Zong WX. Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin. (2021) EBioMedicine. 69, 103456 Pubmed EBioMedicine PMC Article
Petkovic M, Leal EC, Alves I, Bose C, Palade PT, Singh P, Awasthi S, Børsheim E, Dalgaard LT, Singh SP and Carvalho E. Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway. (2021) J Nutr Biochem. 108817 Pubmed J Nutr Biochem
Xiong J, Kuang X, Lu T, Yu K, Liu X, Zhang Z, Wang W, Zhao L, Fang Q, Wu D and Wang J. Correction: C3a and C5a facilitates the metastasis of myeloma cells by activating Nrf2. (2021) Cancer Gene Ther. Pubmed Cancer Gene Ther
Alshammari GM, Al-Qahtani WH, AlFaris NA, Albekairi NA, Alqahtani S, Eid R, Yagoub AEA, Al-Harbi LN and Yahya MA. Quercetin alleviates cadmium chloride-induced renal damage in rats by suppressing endoplasmic reticulum stress through SIRT1-dependent deacetylation of Xbp-1s and eIF2α. (2021) Biomed Pharmacother. 141, 111862 Pubmed Biomed Pharmacother
Cai Y, Wang B, Xu W, Liu K, Gao Y, Guo C, Chen J, Kamal MA and Yuan C. Endometrial Cancer: genetic, metabolic characteristics, therapeutic strategies and nanomedicine. (2021) Curr Med Chem. Pubmed Curr Med Chem
Li L, Zhang Q, Zhang X, Xu X, Wang X, Huang X, Wang T, Jiang Z, Xiao L, Zhang L and Sun L. Protective effects of Nrf2 against sepsis-induced hepatic injury. (2021) Life Sci. 282, 119807 Pubmed Life Sci
Mukherjee S, Ghosh S, Choudhury S, Gupta P, Adhikary A and Chattopadhyay S. Pomegranate Polyphenols Attenuate Inflammation and Hepatic Damage in Tumor-Bearing Mice: Crucial Role of NF-κB and the Nrf2/GSH Axis. (2021) J Nutr Biochem. 108812 Pubmed J Nutr Biochem
Zhao J, Xiao X, Li Y, Gao X, Zhang X, Liu Z, Yi Y, Fu X, Wang H, Guan Y, Xia X, Zhang W and Huang J. The prevalence of HLA-I LOH in Chinese pan-cancer patients and genomic features of patients harboring HLA-I LOH. (2021) Hum Mutat. Pubmed Hum Mutat
Singh G, Haileselassie Y, Ji AR, Maecker HT, Sinha SR, Brim H, Habtezion A and Ashktorab H. Protective Effect of Saffron in Mouse Colitis Models Through Immune Modulation. (2021) Dig Dis Sci. Pubmed Dig Dis Sci
van der Merwe M, van Niekerk G, Fourie C, du Plessis M and Engelbrecht AM. The impact of mitochondria on cancer treatment resistance. (2021) Cell Oncol (Dordr). Pubmed Cell Oncol (Dordr)
Kalyankumarraju M, Puppala ER, Ahmed S, Jagadeesh Kumar G, Tene K, N P S, Sahu BD, Barua CC and Naidu VGM. Zanthoxylum alatum Roxb. seed extract ameliorates stress aggravated DSS-induced ulcerative colitis in mice: Plausible role on NF-κB signaling axis. (2021) J Ethnopharmacol. 279, 114385 Pubmed J Ethnopharmacol
El-Shahawy AAG, Abdel-Moneim A, Ebeid ASM, Eldin ZE and Zanaty MI. A novel layered double hydroxide-hesperidin nanoparticles exert antidiabetic, antioxidant and anti-inflammatory effects in rats with diabetes. (2021) Mol Biol Rep. Pubmed Mol Biol Rep
Wang YZ, Fei DD, Zhang Y, Zhang XG, Wang Y and Wang QT. [Role and mechanism of low-dose lipopolysaccharide-treated human periodontal ligament stem cells on the expression of macrophage pro-inflammatory factors]. (2021) Zhonghua Kou Qiang Yi Xue Za Zhi. 56, 672-678 Pubmed Zhonghua Kou Qiang Yi Xue Za Zhi
Wang S, Yi X, Wu Z, Guo S, Dai W, Wang H, Shi Q, Zeng K, Guo W and Li C. CAMKK2 defines ferroptosis sensitivity of melanoma cells by regulating AMPK-Nrf2 pathway. (2021) J Invest Dermatol. Pubmed J Invest Dermatol
Yang X, Zhi J, Leng H, Chen Y, Gao H, Ma J, Ji J and Hu Q. The piperine derivative HJ105 inhibits Aβ-induced neuroinflammation and oxidative damage via the Keap1-Nrf2-TXNIP axis. (2021) Phytomedicine. 87, 153571 Pubmed Phytomedicine
Mohammadi H and Ashari S. Mechanistic insight into toxicity of phthalates, the involved receptors, and the role of Nrf2, NF-κB, and PI3K/AKT signaling pathways. (2021) Environ Sci Pollut Res Int. 28, 35488-35527 Pubmed Environ Sci Pollut Res Int
Pahlke G, Ahlberg K, Oertel A, Janson-Schaffer T, Grabher S, Mock HP, Matros A and Marko D. Antioxidant Effects of Elderberry Anthocyanins in Human Colon Carcinoma Cells: A Study on Structure-Activity Relationships. (2021) Mol Nutr Food Res. e2100229 Pubmed Mol Nutr Food Res
Liang Z, Zhao W, Li X, Wang L, Meng L and Yu R. Cisplatin synergizes with PRLX93936 to induce ferroptosis in non-small cell lung cancer cells. (2021) Biochem Biophys Res Commun. 569, 79-85 Pubmed Biochem Biophys Res Commun
Goncalves J, Moog S, Morin A, Gentric G, Müller S, Morrell AP, Kluckova K, Stewart TJ, Andoniadou CL, Lussey-Lepoutre C, Bénit P, Thakker A, Vettore L, Roberts J, Rodriguez R, Mechta-Grigoriou F, Gimenez-Roqueplo AP, Letouzé E, Tennant DA and Favier J. Loss of SDHB Promotes Dysregulated Iron Homeostasis, Oxidative Stress, and Sensitivity to Ascorbate. (2021) Cancer Res. 81, 3480-3494 Pubmed Cancer Res
Akaishi R, Fujishima F, Ishida H, Tsunokake J, Yamauchi T, Gokon Y, Ueki S, Fukutomi T, Okamoto H, Takaya K, Sato C, Taniyama Y, Nakamura T, Nakaya N, Kamei T and Sasano H. HO-1 in lymph node metastasis predicted overall survival in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiation therapy. (2021) Cancer Rep (Hoboken). e1477 Pubmed Cancer Rep (Hoboken)
Sanders OD, Rajagopal L and Rajagopal JA. Does oxidatively damaged DNA drive amyloid-β generation in Alzheimer's disease? A hypothesis. (2021) J Neurogenet. 1-7 Pubmed J Neurogenet
Meeran MFN, Azimullah S, Mamoudh HH, Sharma C, Kumar S, Goyal SN and Ojha S. Nerolidol, a Sesquiterpene from the Essential Oils of Aromatic Plants, Attenuates Doxorubicin-Induced Chronic Cardiotoxicity in Rats. (2021) J Agric Food Chem. 69, 7334-7343 Pubmed J Agric Food Chem
Li YC, Hao JC, Shang B, Zhao C, Wang LJ, Yang KL, He XZ, Tian QQ, Wang ZL, Jing HL, Li Y and Cao YJ. Neuroprotective effects of aucubin on hydrogen peroxide-induced toxicity in human neuroblastoma SH-SY5Y cells via the Nrf2/HO-1 pathway. (2021) Phytomedicine. 87, 153577 Pubmed Phytomedicine
Li X, Mu J, Lin Y, Zhao J and Meng X. Combination of cyanidin-3-O-glucoside and cisplatin induces oxidative stress and apoptosis in HeLa cells by reducing activity of endogenous antioxidants, increasing bax/bcl-2 mRNA expression ratio, and downregulating Nrf2 expression. (2021) J Food Biochem. 45, e13806 Pubmed J Food Biochem
Yin QH, Zhou Y and Li ZHY. Suppresses Cell Proliferation and Apoptosis via Regulation of SIRT1/PGC-1α/NRF2 Axis in Pancreatic Cancer. (2021) Cell J. 23, 199-210 Pubmed Cell J PMC Article
Jia L, Hao H, Wang C and Wei J. Etomidate attenuates hyperoxia-induced acute lung injury in mice by modulating the Nrf2/HO-1 signaling pathway. (2021) Exp Ther Med. 22, 785 Pubmed Exp Ther Med PMC Article
Sugimoto M, Ko R, Goshima H, Koike A, Shibano M and Fujimori K. Formononetin attenuates HO-induced cell death through decreasing ROS level by PI3K/Akt-Nrf2-activated antioxidant gene expression and suppressing MAPK-regulated apoptosis in neuronal SH-SY5Y cells. (2021) Neurotoxicology. 85, 186-200 Pubmed Neurotoxicology
Hu YW, Liu Y, Guo EY, Wang YY, Xu WQ, Gao Y, Jiang XY, Feng F, Xu J and Liu WY. Naphtho-γ-pyrone Dimers from an Endozoic and the Effects of Coisolated Monomers in Combination with Cisplatin on a Cisplatin-Resistant A549 Cell Line. (2021) J Nat Prod. 84, 1889-1897 Pubmed J Nat Prod
Naß J, Abdelfatah S and Efferth T. The triterpenoid ursolic acid ameliorates stress in Caenorhabditis elegans by affecting the depression-associated genes skn-1 and prdx2. (2021) Phytomedicine. 88, 153598 Pubmed Phytomedicine
Wu X, Xu J, Cai Y, Yang Y, Liu Y and Cao S. Cytoprotection against Oxidative Stress by Methylnissolin-3--β-d-glucopyranoside from Mainly via the Activation of the Nrf2/HO-1 Pathway. (2021) Molecules. 26, Pubmed Molecules PMC Article
Zhang D, Hou Z, Aldrich KE, Lockwood L, Odom AL and Liby KT. A novel Nrf2 pathway inhibitor sensitizes Keap1-mutant lung cancer cells to chemotherapy. (2021) Mol Cancer Ther. Pubmed Mol Cancer Ther
Zhao X, Wang J, Deng Y, Liao L, Zhou M, Peng C and Li Y. Quercetin as a protective agent for liver diseases: A comprehensive descriptive review of the molecular mechanism. (2021) Phytother Res. Pubmed Phytother Res
Kong C, Yan X, Zhu Y, Zhu H, Luo Y, Liu P, Ferrandon S, Kalady MF, Gao R, He J, Yin F, Qv X, Zheng J, Gao Y, Wei Q, Ma Y, Liu JY and Qin H. Fusobacterium nucleatum promotes the development of colorectal cancer by activating a cytochrome P450/epoxyoctadecenoic acid axis via TLR4/Keap1/NRF2 signaling. (2021) Cancer Res. Pubmed Cancer Res
Lalrinzuali K, Vabeiryureilai M and Jagetia GC. Sonapatha (Oroxylum indicum) mediates cytotoxicity in cultured HeLa cells by inducing apoptosis and suppressing NF-κB, COX-2, RASSF7 and NRF2. (2021) Bioorg Chem. 114, 105126 Pubmed Bioorg Chem
Fujihara KM, Zhang BZ and Clemons NJ. Opportunities for Ferroptosis in Cancer Therapy. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article
Jiao Y, Wang G, Li D, Li H, Liu J, Yang X and Yang W. Okadaic Acid Exposure Induced Neural Tube Defects in Chicken () Embryos. (2021) Mar Drugs. 19, Pubmed Mar Drugs PMC Article
Đurašević S, Pejić S, Grigorov I, Nikolić G, Mitić-Ćulafić D, Dragićević M, Đorđević J, Todorović Vukotić N, Đorđević N, Todorović A, Drakulić D, Veljković F, Pajović SB and Todorović Z. Effects of C60 Fullerene on Thioacetamide-Induced Rat Liver Toxicity and Gut Microbiome Changes. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article
Storz L, Walther P, Chemnitzer O, Lyros O, Niebisch S, Mehdorn M, Jansen-Winkeln B, Moulla Y, Büch T, Gockel I and Thieme R. Nrf2/Keap1-Pathway Activation and Reduced Susceptibility to Chemotherapy Treatment by Acidification in Esophageal Adenocarcinoma Cells. (2021) Cancers (Basel). 13, Pubmed Cancers (Basel) PMC Article
Jenkins T and Gouge J. Nrf2 in Cancer, Detoxifying Enzymes and Cell Death Programs. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel)
Tsakonas G, Martín-Bernabé A, Rounis K, Moreno-Ruiz P, Botling J, De Petris L, Ylipää A, Mezheyeuski A, Micke P, Östman A and Ekman S. High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC. (2021) Cancers (Basel). 13, Pubmed Cancers (Basel) PMC Article
D'Amico R, Genovese T, Cordaro M, Siracusa R, Gugliandolo E, Peritore AF, Interdonato L, Crupi R, Cuzzocrea S, Di Paola R, Fusco R and Impellizzeri D. Palmitoylethanolamide/Baicalein Regulates the Androgen Receptor Signaling and NF-κB/Nrf2 Pathways in Benign Prostatic Hyperplasia. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel)
Koppula P, Olszewski K, Zhang Y, Kondiparthi L, Liu X, Lei G, Das M, Fang B, Poyurovsky MV and Gan B. deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition. (2021) iScience. 24, 102649 Pubmed iScience PMC Article
Ito A, Nasako H, Akizuki R, Takashina Y, Eguchi H, Matsunaga T, Yoshino Y, Endo S and Ikari A. Elevation of Chemosensitivity of Lung Adenocarcinoma A549 Spheroid Cells by Claudin-2 Knockdown through Activation of Glucose Transport and Inhibition of Nrf2 Signal. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci PMC Article
Chen LY, Cheng HL, Kuan YH, Liang TJ, Chao YY and Lin HC. Therapeutic Potential of Luteolin on Impaired Wound Healing in Streptozotocin-Induced Rats. (2021) Biomedicines. 9, Pubmed Biomedicines
Wang XH, Ao QG and Cheng QL. Caloric restriction inhibits renal artery ageing by reducing endothelin-1 expression. (2021) Ann Transl Med. 9, 979 Pubmed Ann Transl Med PMC Article
Chun KS, Raut PK, Kim DH and Surh YJ. Role of chemopreventive phytochemicals in NRF2-mediated redox homeostasis in humans. (2021) Free Radic Biol Med. Pubmed Free Radic Biol Med
Liu GY, Zhang W, Chen XC, Wu WJ and Wan SQ. Diagnostic and Prognostic Significance of Keap1 mRNA Expression for Lung Cancer Based on Microarray and Clinical Information from Oncomine Database. (2021) Curr Med Sci. 41, 597-609 Pubmed Curr Med Sci
Lin HY, Liao KH, Ko CY, Chen GY, Hsu SP, Hung CY and Hsu TI. 17β-estradiol induces temozolomide resistance through NRF2-mediated redox homeostasis in glioblastoma. (2021) Free Radic Biol Med. 172, 430-440 Pubmed Free Radic Biol Med
Hagiwara M, Fushimi A, Yamashita N, Bhattacharya A, Rajabi H, Long MD, Yasumizu Y, Oya M, Liu S and Kufe D. MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells. (2021) Oncogene. Pubmed Oncogene
Liang KH and Wang ML. Deep proteogenomic investigations elucidate the NRF2 antioxidant mechanism as a major driving mechanism of lung adenocarcinoma in Asia. (2021) J Chin Med Assoc. Pubmed J Chin Med Assoc
Xiao Z, Zheng YB, Dao WX, Luo JF, Deng WH, Yan RC and Liu JS. MicroRNA-328-3p facilitates the progression of gastric cancer via KEAP1/NRF2 axis. (2021) Free Radic Res. 1-11 Pubmed Free Radic Res
Zhuo Y, Yuan R, Chen X, He J, Chen Y, Zhang C, Sun K, Yang S, Liu Z and Gao H. Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway. (2021) Chin Med. 16, 48 Pubmed Chin Med PMC Article
Gao L, Morine Y, Yamada S, Saito Y, Ikemoto T, Tokuda K, Miyazaki K, Okikawa S, Takasu C and Shimada M. The BAFF/NFκB axis is crucial to interactions between sorafenib-resistant HCC cells and cancer-associated fibroblasts. (2021) Cancer Sci. Pubmed Cancer Sci
Guo SP, Chang HC, Lu LS, Liu DZ and Wang TJ. Activation of kelch-like ECH-associated protein 1/nuclear factor erythroid 2-related factor 2/antioxidant response element pathway by curcumin enhances the anti-oxidative capacity of corneal endothelial cells. (2021) Biomed Pharmacother. 141, 111834 Pubmed Biomed Pharmacother
Zhang C, Li L, Hou S, Shi Z, Xu W, Wang Q, He Y, Gong Y, Fang Z and Yang Y. Astragaloside IV inhibits hepatocellular carcinoma by continually suppressing the development of fibrosis and regulating pSmad3C/3L and Nrf2/HO-1 pathways. (2021) J Ethnopharmacol. 279, 114350 Pubmed J Ethnopharmacol
Bischoff-Kont I and Fürst R. Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes. (2021) Pharmaceuticals (Basel). 14, Pubmed Pharmaceuticals (Basel) PMC Article
Ren Y, Jiang W, Luo C, Zhang X and Huang M. Atractylenolide III Ameliorates TNBS-Induced Intestinal Inflammation in Mice by Reducing Oxidative Stress and Regulating Intestinal Flora. (2021) Chem Biodivers. Pubmed Chem Biodivers
Shavakandi SM, Ranjbaran M, Nabavizadeh F, Vali R, Sehati F and Ashabi G. Dimethyl fumarate protects the aged brain following chronic cerebral hypoperfusion-related ischemia in rats in Nrf2-dependent manner. (2021) Nutr Neurosci. 1-11 Pubmed Nutr Neurosci
Ren B, Feng J, Yang N, Guo Y, Chen C and Qin Q. Ginsenoside Rg3 attenuates angiotensin II-induced myocardial hypertrophy through repressing NLRP3 inflammasome and oxidative stress via modulating SIRT1/NF-κB pathway. (2021) Int Immunopharmacol. 98, 107841 Pubmed Int Immunopharmacol
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