English: Graph of Nrf2 publications (pubmed se...

English: Graph of Nrf2 publications (pubmed search) by year (Photo credit: Wikipedia)

There are currently over 2300 articles (peer reviewed clinical reviews and studies) on Pubmed.gov on the topic of NRF2 Activation. There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to Pubmed.gov and type in the name of their product. Pubmed is a website operated by the National Institute of Health (NIH).  PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources. Last 200 NRF-2 Studies published on Pubmed
El-Far YM, Khodir AE, Noor AO, Almasri DM, Bagalagel AA, Diri RM, Kutbi HI and Al-Gayyar MMH. Selective cytotoxic activity and protective effects of sodium ascorbate against hepatocellular carcinoma through its effect on oxidative stress and apoptosis and . (2020) Redox Rep.. 25, 17-25 Pubmed Redox Rep.
Zhang X, Feng J, Su S and Huang L. Hepatoprotective effects of aqueous ethanol extract against CCl-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling. (2020) Pharm Biol. 58, 239-246 Pubmed Pharm Biol
Polet M, Laloux L, Cambier S, Ziebel J, Gutleb AC and Schneider YJ. Soluble silver ions from silver nanoparticles induce a polarised secretion of interleukin-8 in differentiated Caco-2 cells. (2020) Toxicol. Lett.. 325, 14-24 Pubmed Toxicol. Lett.
Guan X, Zheng X, Vong CT, Zhao J, Xiao J, Wang Y and Zhong Z. Combined effects of berberine and evodiamine on colorectal cancer cells and cardiomyocytes in vitro. (2020) Eur. J. Pharmacol.. 875, 173031 Pubmed Eur. J. Pharmacol.
Iuchi K, Tasaki Y, Shirai S and Hisatomi H. Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling. (2020) Biomed. Pharmacother.. 125, 109928 Pubmed Biomed. Pharmacother.
Jin F, Chen X, Yan H, Xu Z, Yang B, Luo P and He Q. Bisdemethoxycurcumin attenuates cisplatin-induced renal injury through anti-apoptosis, anti-oxidant and anti-inflammatory. (2020) Eur. J. Pharmacol.. 874, 173026 Pubmed Eur. J. Pharmacol.
Chen Y, Sun Y, Zhao W, Ma Y, Yan Z and Nie X. Elevated SRC3 expression predicts pemetrexed resistance in lung adenocarcinoma. (2020) Biomed. Pharmacother.. 125, 109958 Pubmed Biomed. Pharmacother.
Liu YP, Shao SJ and Guo HD. Schwann cells apoptosis is induced by high glucose in diabetic peripheral neuropathy. (2020) Life Sci.. 248, 117459 Pubmed Life Sci.
Wang H, Tu WJ, Xiao C, Dong MX, Ye YT, Deng J, Wang Y, Sha H and Liu Q. Nrf2 played an important role in radiation protection effect of low-level laser exposed on umbilical cord mesenchymal stem cell. (2020) Tissue Cell. 63, 101329 Pubmed Tissue Cell
Zhou Y, Zhou Y, Wang K, Li T, Yang M, Wang R, Chen Y, Cao M and Hu R. Flumethasone enhances the efficacy of chemotherapeutic drugs in lung cancer by inhibiting Nrf2 signaling pathway. (2020) Cancer Lett.. 474, 94-105 Pubmed Cancer Lett.
Costanzo M, Romeo A, Cisterna B, Calderan L, Bernardi P, Covi V, Tabaracci G and Malatesta M. Ozone at low concentrations does not affect motility and proliferation of cancer cells in vitro. (2020) Eur J Histochem. 64, Pubmed Eur J Histochem
Sami-Ur-Rasheed M, Tripathi MK, Patel DK and Singh MP. Resveratrol regulates Nrf2-mediated expression of antioxidant and xenobiotic metabolizing enzymes in pesticides-induced Parkinsonism. (2020) Protein Pept. Lett.. Pubmed Protein Pept. Lett.
Li HN, Zhao LL, Zhou DY and Chen DQ. Ganoderma Lucidum Polysaccharides Ameliorates Hepatic Steatosis and Oxidative Stress in db/db Mice via Targeting Nuclear Factor E2 (Erythroid-Derived 2)-Related Factor-2/Heme Oxygenase-1 (HO-1) Pathway. (2020) Med. Sci. Monit.. 26, e921905 Pubmed Med. Sci. Monit.
Wu R, Zhang H, Zhao M, Li J, Hu Y, Fu J, Pi J, Wang H and Xu Y. Nrf2 in keratinocytes protects against skin fibrosis via regulating epidermal lesion and inflammatory response. (2020) Biochem. Pharmacol.. 174, 113846 Pubmed Biochem. Pharmacol.
Hindam MO, Sayed RH, Skalicka-Woźniak K, Budzyńska B and El Sayed NS. Xanthotoxin and umbelliferone attenuate cognitive dysfunction in a streptozotocin-induced rat model of sporadic Alzheimer's disease: The role of JAK2/STAT3 and Nrf2/HO-1 signalling pathway modulation. (2020) Phytother Res. Pubmed Phytother Res
Madide T, Somboro AM, Amoako DG, Khumalo HM and Khan RB. Di-2-picolylamine triggers caspase-independent apoptosis by inducing oxidative stress in human liver hepatocellular carcinoma cells. (2020) Biotechnol. Appl. Biochem.. Pubmed Biotechnol. Appl. Biochem.
Sabitha R, Nishi K, Gunasekaran VP, Agilan B, David E, Annamalai G, Vinothkumar R, Perumal M, Subbiah L and Ganeshan M. p-Coumaric acid attenuates alcohol exposed hepatic injury through MAPKs, apoptosis and Nrf2 signaling in experimental models. (2020) Chem. Biol. Interact.. 321, 109044 Pubmed Chem. Biol. Interact.
Abdelzaher WY, AboBakr Ali AHS and El-Tahawy NFG. Mast cell stabilizer modulates Sirt1/Nrf2/TNF pathway and inhibits oxidative stress, inflammation, and apoptosis in rat model of cyclophosphamide hepatotoxicity. (2020) Immunopharmacol Immunotoxicol. 42, 101-109 Pubmed Immunopharmacol Immunotoxicol
Zhou W, Fang C, Zhang L, Wang Q, Li D and Zhu D. Thioredoxin domain-containing protein 9 (TXNDC9) contributes to oxaliplatin resistance through regulation of autophagy-apoptosis in colorectal adenocarcinoma. (2020) Biochem. Biophys. Res. Commun.. 524, 582-588 Pubmed Biochem. Biophys. Res. Commun.
Park CW, Ahn JH, Lee TK, Park YE, Kim B, Lee JC, Kim DW, Shin MC, Park Y, Cho JH, Ryoo S, Kim YM, Won MH and Park JH. Post-treatment with oxcarbazepine confers potent neuroprotection against transient global cerebral ischemic injury by activating Nrf2 defense pathway. (2020) Biomed. Pharmacother.. 124, 109850 Pubmed Biomed. Pharmacother.
Lin H and Wang X. The effects of gasotransmitters on bronchopulmonary dysplasia. (2020) Eur. J. Pharmacol.. 873, 172983 Pubmed Eur. J. Pharmacol.
Ramesh PS, Devegowda D, Singh A and Thimmulappa RK. NRF2, p53, and p16: Predictive biomarkers to stratify human papillomavirus associated head and neck cancer patients for de-escalation of cancer therapy. (2020) Crit. Rev. Oncol. Hematol.. 148, 102885 Pubmed Crit. Rev. Oncol. Hematol.
Wang X, Saud SM, Wang F, He S, Zhang X, Hua B and Li W. Protective effect of ShaoYao decoction on colitis-associated colorectal cancer by inducing Nrf2 signaling pathway. (2020) J Ethnopharmacol. 252, 112600 Pubmed J Ethnopharmacol
Wing Leung H, Ting Lau EY, Ning Leung CO, Leng Lei MM, Kit Mok EH, Ma VWS, Shing Cho WC, Lin Ng IO, Ping Yun J, Hang Cai S, Jian Yu H, Ma S and Wah Lee TK. NRF2/SHH signaling cascade promotes tumor-initiating cell lineage and drug resistance in hepatocellular carcinoma. (2020) Cancer Lett.. 476, 48-56 Pubmed Cancer Lett.
Gao X, Mi Y, Guo N, Luan J, Xu H, Hu Z, Wang N, Zhang D, Gou X and Xu L. The mechanism of propofol in cancer development: An updated review. (2020) Asia Pac J Clin Oncol. 16, e3-e11 Pubmed Asia Pac J Clin Oncol
Hou W, Zhu X, Liu J and Map J. Inhibition of miR-153 ameliorates ischemia/reperfusion-induced cardiomyocytes apoptosis by regulating Nrf2/HO-1 signaling in rats. (2020) Biomed Eng Online. 19, 15 Pubmed Biomed Eng Online PMC Article
Feng SL, Luo HB, Cai L, Zhang J, Wang D, Chen YJ, Zhan HX, Jiang ZH and Xie Y. Ginsenoside Rg5 overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter: and study. (2020) J Ginseng Res. 44, 247-257 Pubmed J Ginseng Res PMC Article
Petragnano F, Pietrantoni I, Di Nisio V, Fasciani I, Del Fattore A, Capalbo C, Cheleschi S, Tini P, Orelli S, Codenotti S, Mazzei MA, D'Ermo G, Pannitteri G, Tombolini M, De Cesaris P, Riccioli A, Filippini A, Milazzo L, Vulcano F, Fanzani A, Maggio R, Marampon F and Tombolini V. Modulating the dose-rate differently affects the responsiveness of human epithelial prostate- and mesenchymal rhabdomyosarcoma-cancer cell line to radiation. (2020) Int. J. Radiat. Biol.. 1-13 Pubmed Int. J. Radiat. Biol.
Wang Z, Sun W, Sun X, Wang Y and Zhou M. Kaempferol ameliorates Cisplatin induced nephrotoxicity by modulating oxidative stress, inflammation and apoptosis via ERK and NF-κB pathways. (2020) AMB Express. 10, 58 Pubmed AMB Express PMC Article
Lou C, Deng A, Zheng H, Sun G, Zhao H, Li A, Liu Q, Li Y and Lv Z. Pinitol suppresses TNF-α-induced chondrocyte senescence. (2020) Cytokine. 130, 155047 Pubmed Cytokine
Wang S, Cheng H, Wang L, Zhao R and Guan D. Overexpression of or Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci
Cho YC, Park J and Cho S. Anti-Inflammatory and Anti-Oxidative Effects of luteolin-7--glucuronide in LPS-Stimulated Murine Macrophages through TAK1 Inhibition and Nrf2 Activation. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci
Munakarmi S, Chand L, Shin HB, Jang KY and Jeong YJ. Indole-3-Carbinol Derivative DIM Mitigates Carbon Tetrachloride-Induced Acute Liver Injury in Mice by Inhibiting Inflammatory Response, Apoptosis and Regulating Oxidative Stress. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci
Wang Z, Zuo Z, Li L, Ren S, Gao T, Fu J, Hou Y, Chen Y and Pi J. Nrf2 in adipocytes. (2020) Arch. Pharm. Res.. 43, 350-360 Pubmed Arch. Pharm. Res.
Tao M, Liu T, You Q and Jiang Z. p62 as a therapeutic target for tumor. (2020) Eur J Med Chem. 193, 112231 Pubmed Eur J Med Chem
Shin JW, Chun KS, Kim DH, Kim SJ, Kim SH, Cho NC, Na HK and Surh YJ. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification. (2020) Biochem. Pharmacol.. 173, 113820 Pubmed Biochem. Pharmacol.
Roos NJ, Duthaler U, Bouitbir J and Krähenbühl S. The uricosuric benzbromarone disturbs the mitochondrial redox homeostasis and activates the NRF2 signaling pathway in HepG2 cells. (2020) Free Radic. Biol. Med.. 152, 216-226 Pubmed Free Radic. Biol. Med.
Ragab D, Abdallah DM and El-Abhar HS. The dual reno- and neuro-protective effects of dimethyl fumarate against uremic encephalopathy in a renal ischemia/reperfusion model. (2020) Pharmacol Rep. Pubmed Pharmacol Rep
Li D, Tian H, Li X, Mao L, Zhao X, Lin J, Lin S, Xu C, Liu Y, Guo Y and Mei X. Zinc promotes functional recovery after spinal cord injury by activating Nrf2/HO-1 defense pathway and inhibiting inflammation of NLRP3 in nerve cells. (2020) Life Sci.. 245, 117351 Pubmed Life Sci.
Li D, Shao R, Wang N, Zhou N, Du K, Shi J, Wang Y, Zhao Z, Ye X, Zhang X and Xu H. Sulforaphane Activates a lysosome-dependent transcriptional program to mitigate oxidative stress. (2020) Autophagy. 1-15 Pubmed Autophagy
Yang CM, Lin CC, Yang CC, Cho RL and Hsiao LD. Mevastatin-Induced AP-1-Dependent HO-1 Expression Suppresses Vascular Cell Adhesion Molecule-1 Expression and Monocyte Adhesion on Human Pulmonary Alveolar Epithelial Cells Challenged with TNF-α. (2020) Biomolecules. 10, Pubmed Biomolecules
Sies H and Jones DP. Reactive oxygen species (ROS) as pleiotropic physiological signalling agents. (2020) Nat. Rev. Mol. Cell Biol.. Pubmed Nat. Rev. Mol. Cell Biol.
Nam LB and Keum YS. Regulation of NRF2 by Na/K-ATPase: implication of tyrosine phosphorylation of Src. (2020) Free Radic. Res.. 1-11 Pubmed Free Radic. Res.
Banas K, Rivera-Torres N, Bialk P, Yoo BC and Kmiec EB. Kinetics of nuclear uptake and site-specific DNA cleavage during CRISPR-directed gene editing in solid tumor cells. (2020) Mol. Cancer Res.. Pubmed Mol. Cancer Res.
Shrishrimal S, Chatterjee A, Kosmacek EA, Davis PJ, McDonald JT and Oberley-Deegan RE. Manganese porphyrin, MnTE-2-PyP, treatment protects the prostate from radiation-induced fibrosis (RIF) by activating the NRF2 signaling pathway and enhancing SOD2 and sirtuin activity. (2020) Free Radic. Biol. Med.. 152, 255-270 Pubmed Free Radic. Biol. Med.
Mahran YF. New insights into the protection of growth hormone in cisplatin-induced nephrotoxicity: The impact of IGF-1 on the Keap1-Nrf2/HO-1 signaling. (2020) Life Sci.. 117581 Pubmed Life Sci.
Lim JS, Lee SH, Lee SR, Lim HJ, Roh YS, Won EJ, Cho N, Chun C and Cho YC. Inhibitory Effects of Decne. Extract on Inflammatory and Oxidative Responses in LPS-Treated Macrophages. (2020) Molecules. 25, Pubmed Molecules
Cheng Y, Chen Y, Li J, Qu H, Zhao Y, Wen C and Zhou Y. Dietary β-sitosterol regulates serum lipid level and improves immune function, antioxidant status, and intestinal morphology in broilers. (2020) Poult. Sci.. 99, 1400-1408 Pubmed Poult. Sci.
Abedi M, Rahgozar S and Esmaeili A. Iron protects childhood acute lymphoblastic leukemia cells from methotrexate cytotoxicity. (2020) Cancer Med. Pubmed Cancer Med
Kitakaze T, Yuan S, Inoue M, Yoshioka Y, Yamashita Y and Ashida H. 6-(Methylsulfinyl)hexyl isothiocyanate protects acetaldehyde-caused cytotoxicity through the induction of aldehyde dehydrogenase in hepatocytes. (2020) Arch. Biochem. Biophys.. 108329 Pubmed Arch. Biochem. Biophys.
Yao X, Yu S, Jing X, Guo J, Sun K, Guo F and Ye Y. PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway. (2020) Stem Cell Res Ther. 11, 140 Pubmed Stem Cell Res Ther PMC Article
Pajarillo E, Rizor A, Son DS, Aschner M and Lee E. The transcription factor REST up-regulates tyrosine hydroxylase and antiapoptotic genes and protects dopaminergic neurons against manganese toxicity. (2020) J. Biol. Chem.. 295, 3040-3054 Pubmed J. Biol. Chem. PMC Article
Shaukat A, Yang C, Yang Y, Guo YF, Jiang K, Guo S, Liu J, Zhang T, Zhao G, Ma X, Wu Z, Zhou Q, Akhtar M, Zahoor A, Umar T, Shaukat I, Hanif S, Rajput SA, Hassan M, Mehmood K, Hua Z, Xiaoyan W, Nannan Y and Deng G. Ginsenoside Rb 1: A novel therapeutic agent in Staphylococcusaureus-induced Acute Lung Injury with special reference to Oxidative stress and Apoptosis. (2020) Microb. Pathog.. 143, 104109 Pubmed Microb. Pathog.
Jin W, Xue Y, Xue Y, Han X, Song Q, Zhang J, Li Z, Cheng J, Guan S, Sun S and Chu L. Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways. (2020) Biomed. Pharmacother.. 126, 110047 Pubmed Biomed. Pharmacother.
Laurence J, Elhadad S, Gostynska S, Yu Z, Terry H, Varshney R, Fung KM, Choi ME and Ahamed J. HIV protease inhibitor ritonavir induces renal fibrosis and dysfunction: role of platelet-derived TGF-β1 and intervention via anti-oxidant pathways. (2020) AIDS. Pubmed AIDS
Nabih HK. Crosstalk between NRF2 and Dicer through metastasis regulating MicroRNAs; Mir-34a, Mir-200 family and mir-103/107 family. (2020) Arch. Biochem. Biophys.. 108326 Pubmed Arch. Biochem. Biophys.
Gao H, Ye G, Lin Y, Chi Y and Dong S. Benzo[a]pyrene at human blood equivalent level induces human lung epithelial cell invasion and migration via aryl hydrocarbon receptor signaling. (2020) J Appl Toxicol. Pubmed J Appl Toxicol
Martinez RM, Hohmann MS, Longhi-Balbinot DT, Zarpelon AC, Baracat MM, Georgetti SR, Vicentini FTMC, Sassonia RC, Verri WA and Casagrande R. Analgesic activity and mechanism of action of a Beta vulgaris dye enriched in betalains in inflammatory models in mice. (2020) Inflammopharmacology. Pubmed Inflammopharmacology
Lee DY, Yun SM, Song MY, Jung K and Kim EH. Cyanidin Chloride Induces Apoptosis by Inhibiting NF-κB Signaling through Activation of Nrf2 in Colorectal Cancer Cells. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel)
Dong L, Dongzhi Z, Jin Y, Kim YC, Lee DS, Huang S, Panichayupakaranant P and Li B. Wigg. Attenuates Inflammatory Responses in Murine Microglia through the Nrf2/HO-1 and NF-B Signaling Pathways. (2020) Am. J. Chin. Med.. 1-18 Pubmed Am. J. Chin. Med.
Kanai T, Kondo N, Okada M, Sano H, Okumura G, Kijima Y, Ogose A, Kawashima H and Endo N. The JNK pathway represents a novel target in the treatment of rheumatoid arthritis through the suppression of MMP-3. (2020) J Orthop Surg Res. 15, 87 Pubmed J Orthop Surg Res
Li CL, Liu XH, Qiao Y, Ning LN, Li WJ, Sun YS, Liu DS, Gao W and Ma CM. Allicin alleviates inflammation of diabetic macroangiopathy via the Nrf2 and NF-kB pathway. (2020) Eur. J. Pharmacol.. 876, 173052 Pubmed Eur. J. Pharmacol.
Choi EJ and Jeon SM. NRF2-driven redox metabolism takes center stage in cancer metabolism from an outside-in perspective. (2020) Arch. Pharm. Res.. 43, 321-336 Pubmed Arch. Pharm. Res.
Fu X, Li P, Yin W, Ma L, Zhang B, Zhen L, Meng Y, Han L and Wang Y. Overexpression of Nrf2 Protects Against Lipopolysaccharide and Cerulein-Induced Pancreatitis In Vitro and In Vivo. (2020) Pancreas. 49, 420-428 Pubmed Pancreas
Nabeshima T, Hamada S, Taguchi K, Tanaka Y, Matsumoto R, Yamamoto M and Masamune A. deletion accelerates mutant /-driven cholangiocarcinoma. (2020) Am. J. Physiol. Gastrointest. Liver Physiol.. 318, G419-G427 Pubmed Am. J. Physiol. Gastrointest. Liver Physiol.
Jee SC, Kim M and Sung JS. Modulatory Effects of Silymarin on Benzo[a]pyrene-Induced Hepatotoxicity. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci
Li S, Yang Y, Sargsyan D, Wu R, Yin R, Kuo HD, Yang I, Wang L, Cheng D, Ramirez CN, Hudlikar R, Lu Y and Kong AN. Epigenome, transcriptome and protection by sulforaphane at different stages of UVB-induced skin carcinogenesis. (2020) Cancer Prev Res (Phila). Pubmed Cancer Prev Res (Phila)
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Zhang C and Yang KB. BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma. (2020) Cancer Sci.. Pubmed Cancer Sci.
Towers CG, Wodetzki D and Thorburn A. Autophagy-dependent cancer cells circumvent loss of the upstream regulator RB1CC1/FIP200 and loss of LC3 conjugation by similar mechanisms. (2020) Autophagy. 1-9 Pubmed Autophagy
Dai C, Chen X, Li J, Comish P, Kang R and Tang D. Transcription factors in ferroptotic cell death. (2020) Cancer Gene Ther.. Pubmed Cancer Gene Ther.
Ashrafizadeh M, Ahmadi Z, Samarghandian S, Mohammadinejad R, Yaribeygi H, Sathyapalan T and Sahebkar A. MicroRNA-mediated regulation of Nrf2 signaling pathway: Implications in disease therapy and protection against oxidative stress. (2020) Life Sci.. 244, 117329 Pubmed Life Sci.
Lin Z, Fu C, Yan Z, Wu Y, Zhan J, Lou Z, Liao X and Pan J. The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study. (2020) Food Funct. 11, 2654-2666 Pubmed Food Funct
Zhang Z, Xu C, Hao J, Zhang M, Wang Z, Yin T, Lin K, Liu W, Jiang Q, Li Z, Wang D, Mao Z, Tong H and Zhang L. Beneficial consequences of Lupeol on middle cerebral artery-induced cerebral ischemia in the rat involves Nrf2 and P38 MAPK modulation. (2020) Metab Brain Dis. Pubmed Metab Brain Dis
Chen Y, Bian W and Xu B. Pretreatment with dexmedetomidine alleviates lung injury in a rat model of intestinal ischemia reperfusion. (2020) Mol Med Rep. 21, 1233-1241 Pubmed Mol Med Rep PMC Article
Smolková K, Mikó E, Kovács T, Leguina-Ruzzi A, Sipos A and Bai P. Nuclear Factor Erythroid 2-Related Factor 2 in Regulating Cancer Metabolism. (2020) Antioxid. Redox Signal.. Pubmed Antioxid. Redox Signal.
Yang H, Xiang S, Kazi A and Sebti SM. The GTPase KRAS suppresses the p53 tumor suppressor by activating the NRF2-regulated antioxidant defense system in cancer cells. (2020) J. Biol. Chem.. 295, 3055-3063 Pubmed J. Biol. Chem. PMC Article
Zhao J, Niu X, Yu J, Xiao X, Li W, Zang L, Hu Z, Siu-Po Ip P and Li W. Poria cocos polysaccharides attenuated ox-LDL-induced inflammation and oxidative stress via ERK activated Nrf2/HO-1 signaling pathway and inhibited foam cell formation in VSMCs. (2020) Int. Immunopharmacol.. 80, 106173 Pubmed Int. Immunopharmacol.
Amara I, Scuto M, Zappalà A, Ontario ML, Petralia A, Abid-Essefi S, Maiolino L, Signorile A, Trovato Salinaro A and Calabrese V. Prevents DEHP-Induced Mitochondrial Dysfunction and Apoptosis in PC12 Cells. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci
Darband SG, Sadighparvar S, Yousefi B, Kaviani M, Ghaderi-Pakdel F, Mihanfar A, Rahimi Y, Mobaraki K and Majidinia M. Quercetin attenuated oxidative DNA damage through NRF2 signaling pathway in rats with DMH induced colon carcinogenesis. (2020) Life Sci.. 117584 Pubmed Life Sci.
Lu Y, Zhou L, He S, Ren HL, Zhou N and Hu ZM. Lycopene alleviates disc degeneration under oxidative stress through the Nrf2 signaling pathway. (2020) Mol. Cell. Probes. 101559 Pubmed Mol. Cell. Probes
Wan L, Liu J, Huang CB, Sun Y, Zhang XJ and Liu TY. [Effect of Triptolide on Cardiac Function in Arthritic Rats and Its Mechanism]. (2020) Sichuan Da Xue Xue Bao Yi Xue Ban. 51, 207-212 Pubmed Sichuan Da Xue Xue Bao Yi Xue Ban
Gureev AP, Popov VN and Starkov AA. Crosstalk between the mTOR and Nrf2/ARE signaling pathways as a target in the improvement of long-term potentiation. (2020) Exp. Neurol.. 328, 113285 Pubmed Exp. Neurol.
Jingyuan H, Yan L, Wenjing P, Wenqiang J, Bo L, Linghong M, Qunlang Z, Hualiang L and Xianping G. Dietary selenium enhances the growth and anti-oxidant capacity of juvenile blunt snout bream (Megalobrama amblycephala). (2020) Fish Shellfish Immunol.. 101, 115-125 Pubmed Fish Shellfish Immunol.
Hong Q, Yang Y, Wang Z, Xu L and Yan Z. Longxuetongluo capsule alleviates lipopolysaccharide-induced neuroinflammation by regulating multiple signaling pathways in BV2 microglia cells. (2020) J Chin Med Assoc. 83, 255-265 Pubmed J Chin Med Assoc
Feng F, Cheng P, Xu S, Li N, Wang H, Zhang Y and Wang W. Tanshinone IIA attenuates silica-induced pulmonary fibrosis via Nrf2-mediated inhibition of EMT and TGF-β1/Smad signaling. (2020) Chem. Biol. Interact.. 319, 109024 Pubmed Chem. Biol. Interact.
Yasuda D, Ohe T, Takahashi K, Imamura R, Kojima H, Okabe T, Ichimura Y, Komatsu M, Yamamoto M, Nagano T and Mashino T. Inhibitors of the protein-protein interaction between phosphorylated p62 and Keap1 attenuate chemoresistance in a human hepatocellular carcinoma cell line. (2020) Free Radic. Res.. 1-13 Pubmed Free Radic. Res.
He L, Long J, Zhou X, Liu Y, Li T and Wu X. Serine is required for the maintenance of redox balance and proliferation in the intestine under oxidative stress. (2020) FASEB J.. 34, 4702-4717 Pubmed FASEB J.
Yang Q, Li K, Huang X, Zhao C, Mei Y, Li X, Jiao L and Yang H. lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCF-Mediated Degradation of NRF2 in Pancreatic Cancer. (2020) Mol Ther Nucleic Acids. 19, 974-985 Pubmed Mol Ther Nucleic Acids PMC Article
Riedelberger M, Penninger P, Tscherner M, Seifert M, Jenull S, Brunnhofer C, Scheidl B, Tsymala I, Bourgeois C, Petryshyn A, Glaser W, Limbeck A, Strobl B, Weiss G and Kuchler K. Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection. (2020) Cell Host Microbe. 27, 454-466.e8 Pubmed Cell Host Microbe
Abed DA, Lee S and Hu L. Discovery of disubstituted xylylene derivatives as small molecule direct inhibitors of Keap1-Nrf2 protein-protein interaction. (2020) Bioorg. Med. Chem.. 28, 115343 Pubmed Bioorg. Med. Chem.
Wang W, Zhao H and Chen B. DJ-1 protects retinal pericytes against high glucose-induced oxidative stress through the Nrf2 signaling pathway. (2020) Sci Rep. 10, 2477 Pubmed Sci Rep PMC Article
Guo K, Ge J, Zhang C, Lv MW, Zhang Q, Talukder M and Li JL. `Cadmium induced cardiac inflammation in chicken (Gallus gallus) via modulating cytochrome P450 systems and Nrf2 mediated antioxidant defense. (2020) Chemosphere. 249, 125858 Pubmed Chemosphere
Panieri E, Buha A, Telkoparan-Akillilar P, Cevik D, Kouretas D, Veskoukis A, Skaperda Z, Tsatsakis A, Wallace D, Suzen S and Saso L. Potential Applications of NRF2 Modulators in Cancer Therapy. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel)
Castruccio Castracani C, Longhitano L, Distefano A, Di Rosa M, Pittalà V, Lupo G, Caruso M, Corona D, Tibullo D and Li Volti G. Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells. (2020) Mol. Neurobiol.. Pubmed Mol. Neurobiol.
Yang G, Yin H, Lin F, Gao S, Zhan K, Tong H, Tang X, Pan Q and Gou X. Long noncoding RNA TUG1 regulates prostate cancer cell proliferation, invasion and migration via the Nrf2 signaling axis. (2020) Pathol. Res. Pract.. 152851 Pubmed Pathol. Res. Pract.
Dilruba S, Grondana A, Schiedel AC, Ueno NT, Bartholomeusz C, Cinatl J, McLaughlin KM, Wass MN, Michaelis M and Kalayda GV. Non-Phosphorylatable PEA-15 Sensitises SKOV-3 Ovarian Cancer Cells to Cisplatin. (2020) Cells. 9, Pubmed Cells PMC Article
Li SP, Cheng WN, Li Y, Xu HB, Han H, Li P and Zhang DX. Keap1-targeting microRNA-941 protects endometrial cells from oxygen and glucose deprivation-re-oxygenation via activation of Nrf2 signaling. (2020) Cell Commun. Signal. 18, 32 Pubmed Cell Commun. Signal PMC Article
Abdelaziz RM, Abdelazem AZ, Hashem KS and Attia YA. Protective effects of hesperidin against MTX-induced hepatotoxicity in male albino rats. (2020) Naunyn Schmiedebergs Arch. Pharmacol.. Pubmed Naunyn Schmiedebergs Arch. Pharmacol.
Leung MH, Tsoi H, Gong C, Man EP, Zona S, Yao S, Lam EW and Khoo US. A Splice Variant of NCOR2, BQ323636.1, Confers Chemoresistance in Breast Cancer by Altering the Activity of NRF2. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel)
He F, Antonucci L, Yamachika S, Zhang Z, Taniguchi K, Umemura A, Hatzivassiliou G, Roose-Girma M, Reina-Campos M, Duran A, Diaz-Meco MT, Moscat J, Sun B and Karin M. NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly. (2020) J. Hepatol.. Pubmed J. Hepatol.
Morris AR, Stanton DL, Roman D and Liu AC. Systems Level Understanding of Circadian Integration with Cell Physiology. (2020) J. Mol. Biol.. Pubmed J. Mol. Biol.
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Cucci MA, Grattarola M, Dianzani C, Damia G, Ricci F, Roetto A, Trotta F, Barrera G and Pizzimenti S. Ailanthone increases oxidative stress in CDDP-resistant ovarian and bladder cancer cells by inhibiting of Nrf2 and YAP expression through a post-translational mechanism. (2020) Free Radic. Biol. Med.. 150, 125-135 Pubmed Free Radic. Biol. Med.
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