English: Graph of Nrf2 publications (pubmed se...

English: Graph of Nrf2 publications (pubmed search) by year (Photo credit: Wikipedia)

There are currently over 2300 articles (peer reviewed clinical reviews and studies) on Pubmed.gov on the topic of NRF2 Activation. There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to Pubmed.gov and type in the name of their product. Pubmed is a website operated by the National Institute of Health (NIH).  PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources. Last 200 NRF-2 Studies published on Pubmed
Tao WY, Yu LJ, Jiang S, Cao X, Chen J, Bao XY, Li F, Xu Y and Zhu XL. Neuroprotective effects of ZL006 in Aβ-treated neuronal cells. (2020) Neural Regen Res. 15, 2296-2305 Pubmed Neural Regen Res
Guerrero-Rubio MA, Hernández-García S, Escribano J, Jiménez-Atiénzar M, Cabanes J, García-Carmona F and Gandía-Herrero F. Betalain health-promoting effects after ingestion in Caenorhabditis elegans are mediated by DAF-16/FOXO and SKN-1/Nrf2 transcription factors. (2020) Food Chem. 330, 127228 Pubmed Food Chem
Mao M, Li J, Bi A, Jia H, Li Q, Liu Y, Jiang X, Huang D and Xia S. Thymoquinone ameliorates the PM2.5-induced lung injury in rats. (2020) Exp. Lung Res.. 46, 297-307 Pubmed Exp. Lung Res.
Wan S, Pan Q, Yang G, Kuang J and Luo S. Role of CYP4F2 as a novel biomarker regulating malignant phenotypes of liver cancer cells via the Nrf2 signaling axis. (2020) Oncol Lett. 20, 13 Pubmed Oncol Lett PMC Article
Xiong X, Lu W, Zhang K and Zhou W. Pterostilbene reduces endothelial cell apoptosis by regulation of the Nrf2-mediated TLR-4/MyD88/NF-κB pathway in a rat model of atherosclerosis. (2020) Exp Ther Med. 20, 2090-2098 Pubmed Exp Ther Med PMC Article
Schmidlin CJ, Zeng T, Liu P, Wei Y, Dodson M, Chapman E and Zhang DD. Chronic arsenic exposure enhances metastatic potential via NRF2-mediated upregulation of SOX9. (2020) Toxicol. Appl. Pharmacol.. 402, 115138 Pubmed Toxicol. Appl. Pharmacol.
Panati K, Thimmana LV and Narala VR. Electrophilic nitrated fatty acids are potential therapeutic candidates for inflammatory and fibrotic lung diseases. (2020) Nitric Oxide. 102, 28-38 Pubmed Nitric Oxide
Du Y, Bao J, Zhang MJ, Li LL, Xu XL, Chen H, Feng YB, Peng XQ and Chen FH. Targeting ferroptosis contributes to ATPR-induced AML differentiation via ROS-autophagy-lysosomal pathway. (2020) Gene. 755, 144889 Pubmed Gene
Saeidi S, Kim SJ, Han HJ, Kim SH, Zheng J, Lee HB, Han W, Noh DY, Na HK and Surh YJ. H-Ras induces Nrf2-Pin1 interaction: Implications for breast cancer progression. (2020) Toxicol. Appl. Pharmacol.. 402, 115121 Pubmed Toxicol. Appl. Pharmacol.
Rahaman MS, Banik S, Akter M, Rahman MM, Sikder MT, Hosokawa T, Saito T and Kurasaki M. Curcumin alleviates arsenic-induced toxicity in PC12 cells via modulating autophagy/apoptosis. (2020) Ecotoxicol. Environ. Saf.. 200, 110756 Pubmed Ecotoxicol. Environ. Saf.
Yang PM, Cheng KC, Yuan SH and Wung BS. Carbon monoxide‑releasing molecules protect against blue light exposure and inflammation in retinal pigment epithelial cells. (2020) Int. J. Mol. Med.. 46, 1096-1106 Pubmed Int. J. Mol. Med. PMC Article
An K, Zhang Y, Liu Y, Yan S, Hou Z, Cao M, Liu G, Dong C, Gao J and Liu G. Neferine induces apoptosis by modulating the ROS‑mediated JNK pathway in esophageal squamous cell carcinoma. (2020) Oncol. Rep.. 44, 1116-1126 Pubmed Oncol. Rep. PMC Article
Patra S, Bhol CS, Panigrahi DP, Praharaj PP, Pradhan B, Jena M and Bhutia SK. Gamma irradiation promotes chemo-sensitization potential of gallic acid through attenuation of autophagic flux to trigger apoptosis in NRF2 inactivation signalling pathway. (2020) Free Radic. Biol. Med.. Pubmed Free Radic. Biol. Med.
Liu Y, Zeng Y, Miao Y, Cheng X, Deng S, Hao X, Jiang Y and Wan Q. Relationships among pancreatic beta cell function, the Nrf2 pathway, and IRS2: a cross-sectional study. (2020) Postgrad Med. 1-7 Pubmed Postgrad Med
López-Granero C, Ferrer B, Dos Santos AA, Barrasa A and Aschner M. The BXD21/TyJ recombinant inbred strain as a model for innate inflammatory response in distinct brain regions. (2020) Sci Rep. 10, 13168 Pubmed Sci Rep PMC Article
Al-Megrin WA, Alomar S, Alkhuriji AF, Metwally DM, Mohamed SK, Kassab RB, Abdel Moneim AE and El-Khadragy MF. Luteolin protects against testicular injury induced by lead acetate by activating the Nrf2/HO-1 pathway. (2020) IUBMB Life. 72, 1787-1798 Pubmed IUBMB Life
Arnér ESJ. Effects of Mammalian Thioredoxin Reductase Inhibitors. (2020) Handb Exp Pharmacol. Pubmed Handb Exp Pharmacol
Ohta S. Direct targets and subsequent pathways for molecular hydrogen to exert multiple functions: Focusing on interventions in radical reactions. (2020) Curr. Pharm. Des.. Pubmed Curr. Pharm. Des.
Wang X, Ye T, Xue B, Yang M, Li R, Xu X, Zeng X, Tian N, Bao L and Huang Y. Mitochondrial GRIM-19 deficiency facilitates gastric cancer metastasis through oncogenic ROS-NRF2-HO-1 axis via a NRF2-HO-1 loop. (2020) Gastric Cancer. Pubmed Gastric Cancer
Mo C, Xie S, Zhong W, Zeng T, Huang S, Lai Y, Deng G, Zhou C, Yan W, Chen Y, Huang S, Gao L and Lv Z. Mutual antagonism between indoleamine 2,3-dioxygenase 1 and nuclear factor E2-related factor 2 regulates the maturation status of DCs in liver fibrosis. (2020) Free Radic. Biol. Med.. Pubmed Free Radic. Biol. Med.
Lastra D, Fernández-Ginés R, Manda G and Cuadrado A. Perspectives on the Clinical Development of NRF2-Targeting Drugs. (2020) Handb Exp Pharmacol. Pubmed Handb Exp Pharmacol
Ziv E, Zhang Y, Kelly L, Nikolovski I, Boas FE, Erinjeri JP, Cai L, Petre EN, Brody LA, Covey AM, Getrajdman G, Harding JJ, Sofocleous C, Abou-Alfa GK, Solomon SB, Brown KT and Yarmohammadi H. NRF2 Dysregulation in Hepatocellular Carcinoma and Ischemia: A Cohort Study and Laboratory Investigation. (2020) Radiology. 200201 Pubmed Radiology
Zhang Y, Le Y, Bu P and Cheng X. Regulation of Hox and ParaHox genes by perfluorochemicals in mouse liver. (2020) Toxicology. 441, 152521 Pubmed Toxicology
Ramadori P, Li X and Heikenwalder M. PKCλ/ι Loss Induces Metabolic Reprogramming in Liver Cancer: Hitting Two Birds with One Stone?. (2020) Cancer Cell. 38, 152-154 Pubmed Cancer Cell
Younis NN, Elsherbiny NM, Shaheen MA and Elseweidy MM. Modulation of NADPH oxidase and Nrf2/HO-1 pathway by vanillin in cisplatin-induced nephrotoxicity in rats. (2020) J. Pharm. Pharmacol.. Pubmed J. Pharm. Pharmacol.
Schultrich K, Henderson CJ, Buhrke T and Braeuning A. Effects of 2-MCPD on oxidative stress in different organs of male mice. (2020) Food Chem. Toxicol.. 142, 111459 Pubmed Food Chem. Toxicol.
Shirazi F, Jones RJ, Singh RK, Zou J, Kuiatse I, Berkova Z, Wang H, Lee HC, Hong S, Dick L, Chattopadhyay N and Orlowski RZ. Activating , , and mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma. (2020) Proc. Natl. Acad. Sci. U.S.A.. Pubmed Proc. Natl. Acad. Sci. U.S.A.
Shao Z, Pan Q and Zhang Y. Hepatocellular carcinoma cell-derived extracellular vesicles encapsulated microRNA-584-5p facilitates angiogenesis through PCK1-mediated nuclear factor E2-related factor 2 signaling pathway. (2020) Int. J. Biochem. Cell Biol.. 125, 105789 Pubmed Int. J. Biochem. Cell Biol.
Min JH, Kim MG, Kim SM, Park JW, Chun W, Lee HJ, Oh SR, Ahn KS and Lee JW. 3,4,5-Trihydroxycinnamic acid exerts a protective effect on pulmonary inflammation in an experimental animal model of COPD. (2020) Int. Immunopharmacol.. 85, 106656 Pubmed Int. Immunopharmacol.
Odera JO, Xiong Z, Huang C, Gu N, Yang W, Githang'a J, Odera E, Paiboonrungruang C and Chen X. NRF2/ACSS2 axis mediates the metabolic effect of alcohol drinking on esophageal squamous cell carcinoma. (2020) Biochem. J.. Pubmed Biochem. J.
Yang S, Chu S, Ai Q, Zhang Z, Gao Y, Lin M, Liu Y, Hu Y, Li X, Peng Y, Pan Y, He Q and Chen N. Anti-inflammatory effects of higenamine (Hig) on LPS-activated mouse microglia (BV2) through NF-κB and Nrf2/HO-1 signaling pathways. (2020) Int. Immunopharmacol.. 85, 106629 Pubmed Int. Immunopharmacol.
Huai B and Ding J. Atractylenolide III attenuates Bleomycin-induced experimental pulmonary fibrosis and oxidative stress in rat model via Nrf2/NQO1/HO-1 pathway activation. (2020) Immunopharmacol Immunotoxicol. 1-21 Pubmed Immunopharmacol Immunotoxicol
Lee SE, Kwon K, Oh SW, Park SJ, Yu E, Kim H, Yang S, Park JY, Chung WJ, Cho JY and Lee J. Mechanisms of Resorcinol Antagonism of Benzo[a]pyrene-Induced Damage to Human Keratinocytes. (2020) Biomol Ther (Seoul). Pubmed Biomol Ther (Seoul)
Song IY, Snyder AM, Kim Y, Neely EB, Wade QW and Connor JR. The Nrf2-mediated defense mechanism associated with HFE genotype limits vulnerability to oxidative stress-induced toxicity. (2020) Toxicology. 441, 152525 Pubmed Toxicology
Nna VU, Ujah GA, Suleiman JB, Mohamed M, Nwokocha C, Akpan TJ, Ekuma HC, Fubara VV, Kekung-Asu CB and Osim EE. Tert-butylhydroquinone preserve testicular steroidogenesis and spermatogenesis in cisplatin-intoxicated rats by targeting oxidative stress, inflammation and apoptosis. (2020) Toxicology. 441, 152528 Pubmed Toxicology
Matés JM, Campos-Sandoval JA, de Los Santos-Jiménez J and Márquez J. Glutaminases regulate glutathione and oxidative stress in cancer. (2020) Arch. Toxicol.. 94, 2603-2623 Pubmed Arch. Toxicol.
Kudo Y, Sugimoto M, Arias E, Kasashima H, Cordes T, Linares JF, Duran A, Nakanishi Y, Nakanishi N, L'Hermitte A, Campos A, Senni N, Rooslid T, Roberts LR, Cuervo AM, Metallo CM, Karin M, Diaz-Meco MT and Moscat J. PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression. (2020) Cancer Cell. 38, 247-262.e11 Pubmed Cancer Cell
Yu H, Wu Z, Wang X, Gao C, Liu R, Kang F and Dai M. Protective effects of combined treatment with mild hypothermia and edaravone against cerebral ischemia/reperfusion injury via oxidative stress and Nrf2 pathway regulation. (2020) Int. J. Oncol.. 57, 500-508 Pubmed Int. J. Oncol. PMC Article
Hayes JD, Dinkova-Kostova AT and Tew KD. Oxidative Stress in Cancer. (2020) Cancer Cell. 38, 167-197 Pubmed Cancer Cell
Wu JL, Liu WX, Wen CG, Qian GM, Hu BQ, Jian SQ, Yang G and Dong J. Effect of microcystin on the expression of Nrf2 and its downstream antioxidant genes from Cristaria plicata. (2020) Aquat. Toxicol.. 225, 105526 Pubmed Aquat. Toxicol.
D'Orazi G, Garufi A and Cirone M. Nuclear factor erythroid 2 (NF-E2) p45-related factor 2 interferes with homeodomain-interacting protein kinase 2/p53 activity to impair solid tumors chemosensitivity. (2020) IUBMB Life. 72, 1634-1639 Pubmed IUBMB Life
Khalaf AA, Hassanen EI, Ibrahim MA, Tohamy AF, Aboseada MA, Hassan HM and Zaki AR. Rosmarinic acid attenuates chromium-induced hepatic and renal oxidative damage and DNA damage in rats. (2020) J. Biochem. Mol. Toxicol.. e22579 Pubmed J. Biochem. Mol. Toxicol.
Narożna M, Krajka-Kuźniak V, Kleszcz R, Bednarczyk-Cwynar B, Szaefer H and Baer-Dubowska W. Activation of the Nrf2 response by oleanolic acid oxime morpholide (3-hydroxyiminoolean-12-en-28-oic acid morpholide) is associated with its ability to induce apoptosis and inhibit proliferation in HepG2 hepatoma cells. (2020) Eur. J. Pharmacol.. 173307 Pubmed Eur. J. Pharmacol.
Aktepe OH, Şahİn TK, GÜner G, Arik Z and YalÇin Ş. Lycopene sensitizes the cervical cancer cells to cisplatin via targeting nuclear factor-kappa B (NF-?B) pathway. (2020) Turk J Med Sci. Pubmed Turk J Med Sci
Song XY, Guo R, Qi XL, Han FY, Lin B, Huang XX, Yao GD and Song SJ. Terpenoids from stigma maydis (Zea mays L.) alleviate hydrogen peroxide-induced SH-SY5Y cell injury by activating Nrf2. (2020) Bioorg. Chem.. 102, 104131 Pubmed Bioorg. Chem.
Ansari MY, Ahmad N and Haqqi TM. Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols. (2020) Biomed. Pharmacother.. 129, 110452 Pubmed Biomed. Pharmacother.
Bhattacharjee S, Li J and Dashwood RH. Emerging crosstalk between long non-coding RNAs and Nrf2 signaling. (2020) Cancer Lett.. 490, 154-164 Pubmed Cancer Lett.
Kao YT, Chen YS, Tang KW, Lee JC, Tseng CH, Tzeng CC, Yen CH and Chen YL. Discovery of 4-Anilinoquinolinylchalcone Derivatives as Potential NRF2 Activators. (2020) Molecules. 25, Pubmed Molecules PMC Article
Ji K, Liang H, Ren M, Ge X, Mi H, Pan L and Yu H. The immunoreaction and antioxidant capacity of juvenile blunt snout bream (Megalobrama amblycephala) involves the PI3K/Akt/Nrf2 and NF-κB signal pathways in response to dietary methionine levels. (2020) Fish Shellfish Immunol.. 105, 126-134 Pubmed Fish Shellfish Immunol.
Hayashi M, Kuga A, Suzuki M, Panda H, Kitamura H, Motohashi H and Yamamoto M. Microenvironmental activation of Nrf2 restricts the progression of Nrf2-activated malignant tumors. (2020) Cancer Res.. Pubmed Cancer Res.
Yu Z, Yang L, Deng S and Liang M. Daidzein ameliorates LPS-induced hepatocyte injury by inhibiting inflammation and oxidative stress. (2020) Eur. J. Pharmacol.. 885, 173399 Pubmed Eur. J. Pharmacol.
Park C, Lee H, Noh JS, Jin CY, Kim GY, Hyun JW, Leem SH and Choi YH. Hemistepsin A protects human keratinocytes against hydrogen peroxide-induced oxidative stress through activation of the Nrf2/HO-1 signaling pathway. (2020) Arch. Biochem. Biophys.. 691, 108512 Pubmed Arch. Biochem. Biophys.
Zhu X, Xi C, Ward A, Takezaki M, Shi H, Peterson KR and Pace BS. NRF2 mediates γ-globin gene regulation through epigenetic modifications in a β-YAC transgenic mouse model. (2020) Exp. Biol. Med. (Maywood). 1535370220945305 Pubmed Exp. Biol. Med. (Maywood)
Ahmed K, Zaidi SF, Mati-Ur-Rehman , Rehman R and Kondo T. Hyperthermia and protein homeostasis: Cytoprotection and cell death. (2020) J. Therm. Biol.. 91, 102615 Pubmed J. Therm. Biol.
Pirpour Tazehkand A, Salehi R, Velaei K and Samadi N. The potential impact of trigonelline loaded micelles on Nrf2 suppression to overcome oxaliplatin resistance in colon cancer cells. (2020) Mol. Biol. Rep.. Pubmed Mol. Biol. Rep.
Sakasai-Sakai A, Takata T and Takeuchi M. Intracellular Toxic Advanced Glycation End-Products Promote the Production of Reactive Oxygen Species in HepG2 Cells. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci PMC Article
Liu YC, Peng BR, Hsu KC, El-Shazly M, Shih SP, Lin TE, Kuo FW, Chou YC, Lin HY and Lu MC. 13-Acetoxysarcocrassolide Exhibits Cytotoxic Activity Against Oral Cancer Cells Through the Interruption of the Keap1/Nrf2/p62/SQSTM1 Pathway: The Need to Move Beyond Classical Concepts. (2020) Mar Drugs. 18, Pubmed Mar Drugs
Jasek-Gajda E, Jurkowska H, Jasińska M and Lis GJ. Targeting the MAPK/ERK and PI3K/AKT Signaling Pathways Affects NRF2, Trx and GSH Antioxidant Systems in Leukemia Cells. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel) PMC Article
Emanuele S, Lauricella M, D'Anneo A, Carlisi D, De Blasio A, Di Liberto D and Giuliano M. p62: Friend or Foe? Evidences for and Roles. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci PMC Article
Garg C, Sharma H and Garg M. Skin photo-protection with phytochemicals against photo-oxidative stress, photo-carcinogenesis, signal transduction pathways and extracellular matrix remodeling-An overview. (2020) Ageing Res. Rev.. 62, 101127 Pubmed Ageing Res. Rev.
Kim NY, Cheong SH, Lee KJ, Sok DE and Kim MR. Anti-Inflammatory Effects of Pall Mediated via Regulation of Nrf2/HO-1 and NF-κB Signaling Pathways in LPS-Stimulated RAW 264.7 Macrophages and a TPA-Induced Dermatitis Animal Model. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel) PMC Article
Lu Y, Sun Y, Liu Z, Lu Y, Zhu X, Lan B, Mi Z, Dang L, Li N, Zhan W, Tan L, Pi J, Xiong H, Zhang L and Chen Y. Activation of NRF2 ameliorates oxidative stress and cystogenesis in autosomal dominant polycystic kidney disease. (2020) Sci Transl Med. 12, Pubmed Sci Transl Med
Lin YH, Lin YJ, Chang TH, Chang YH, Lim YP, Chung JG and Hsieh WT. Pipoxolan suppresses the inflammatory factors of NF-κB, AP-1, and STATs, but activates the antioxidative factor Nrf2 in LPS-stimulated RAW 264.7 murine macrophage cells. (2020) Environ. Toxicol.. Pubmed Environ. Toxicol.
Pasqual-Melo G, Nascimento T, Sanches LJ, Blegniski FP, Bianchi JK, Sagwal SK, Berner J, Schmidt A, Emmert S, Weltmann KD, von Woedtke T, Gandhirajan RK, Cecchini AL and Bekeschus S. Plasma Treatment Limits Cutaneous Squamous Cell Carcinoma Development In Vitro and In Vivo. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel)
Cuzziol CI, Castanhole-Nunes MMU, Pavarino ÉC and Goloni-Bertollo EM. MicroRNAs as regulators of VEGFA and NFE2L2 in cancer. (2020) Gene. 759, 144994 Pubmed Gene
Carrillo-Beltrán D, Muñoz JP, Guerrero-Vásquez N, Blanco R, León O, de Souza Lino V, Tapia JC, Maldonado E, Dubois-Camacho K, Hermoso MA, Corvalán AH, Calaf GM, Boccardo E and Aguayo F. Human Papillomavirus 16 E7 Promotes EGFR/PI3K/AKT1/NRF2 Signaling Pathway Contributing to PIR/NF-κB Activation in Oral Cancer Cells. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel)
Yang K, Kim SY, Park JH, Ahn WG, Jung SH, Oh D, Park HC and Choi C. Topical Application of Phlorotannins from Brown Seaweed Mitigates Radiation Dermatitis in a Mouse Model. (2020) Mar Drugs. 18, Pubmed Mar Drugs
Taniguchi S, Elhance A, Van Duzer A, Kumar S, Leitenberger JJ and Oshimori N. Tumor-initiating cells establish an IL-33-TGF-β niche signaling loop to promote cancer progression. (2020) Science. 369, Pubmed Science
Tang P, Liu H, Lin B, Yang W, Chen W, Lu Z, Li P, Gui S, Zhan Y and Lin B. Spatholobi Caulis dispensing granule reduces deep vein thrombus burden through antiinflammation via SIRT1 and Nrf2. (2020) Phytomedicine. 77, 153285 Pubmed Phytomedicine
Haque E, Karim MR, Salam Teeli A, Śmiech M, Leszczynski P, Winiarczyk D, Parvanov ED, Atanasov AG and Taniguchi H. Molecular Mechanisms Underlying Hepatocellular Carcinoma Induction by Aberrant NRF2 Activation-Mediated Transcription Networks: Interaction of NRF2-KEAP1 Controls the Fate of Hepatocarcinogenesis. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci
Gao Y, Li J, Wang J, Li X, Li J, Chu S, Li L, Chen N and Zhang L. Ginsenoside Rg1 prevent and treat inflammatory diseases: A review. (2020) Int. Immunopharmacol.. 87, 106805 Pubmed Int. Immunopharmacol.
Capelletti MM, Manceau H, Puy H and Peoc'h K. Ferroptosis in Liver Diseases: An Overview. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci PMC Article
Karl F, Stoll A, Böttcher-Loschinski R, Böttcher M, Baur R, Jacobs B, Völkl S, Jitschin R, Rösler W, Mackensen A and Mougiakakos D. Impact of Nrf2 expression in reconstituting T-cells of allogeneic hematopoietic stem cell transplanted patients. (2020) Leukemia. Pubmed Leukemia
Shi Q, Cheng Y, Dong X, Zhang M, Pei C and Zhang M. Effects of rhaponticin on retinal oxidative stress and inflammation in diabetes through NRF2/HO-1/NF-κB signalling. (2020) J. Biochem. Mol. Toxicol.. e22568 Pubmed J. Biochem. Mol. Toxicol.
Ma CS, Lv QM, Zhang KR, Tang YB, Zhang YF, Shen Y, Lei HM and Zhu L. NRF2-GPX4/SOD2 axis imparts resistance to EGFR-tyrosine kinase inhibitors in non-small-cell lung cancer cells. (2020) Acta Pharmacol. Sin.. Pubmed Acta Pharmacol. Sin.
Lee K, Kim S, Lee Y, Lee H, Lee Y, Park H, Nahm JH, Ahn S, Yu SJ, Lee K and Kim H. The Clinicopathological and Prognostic Significance of Nrf2 and Keap1 Expression in Hepatocellular Carcinoma. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel)
Zhang E, Huang J, Wang K, Yu Q, Zhu C and Ren H. Pterostilbene Protects Against Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure by Upregulating the Nrf2 Pathway and Inhibiting NF-B, MAPK, and NLRP3 Inflammasome Activation. (2020) J Med Food. Pubmed J Med Food
Li L, Li H, Zhou Q, Lu Y, Chen P, Wang X and Zhao H. Implication of nuclear factor-erythroid 2-like 2/heme oxygenase 1 pathway in the protective effects of coenzyme Q10 against preeclampsia-like in a rat model. (2020) Microcirculation. e12651 Pubmed Microcirculation
Chepikova OE, Malin D, Strekalova E, Lukasheva EV, Zamyatnin AA and Cryns VL. Lysine oxidase exposes a dependency on the thioredoxin antioxidant pathway in triple-negative breast cancer cells. (2020) Breast Cancer Res. Treat.. Pubmed Breast Cancer Res. Treat.
Al-Harbi LN, Subash-Babu P, Binobead MA, Alhussain MH, AlSedairy SA, Aloud AA and Alshatwi AA. Potential Metabolite Nymphayol Isolated from Water Lily () Flower Inhibits MCF-7 Human Breast Cancer Cell Growth via Upregulation of Cdkn2a, pRb2, p53 and Downregulation of PCNA mRNA Expressions. (2020) Metabolites. 10, Pubmed Metabolites
Wu X, Liu C, Li Z, Gai C, Ding D, Chen W, Hao F and Li W. Regulation of GSK3β/Nrf2 signaling pathway modulated erastin-induced ferroptosis in breast cancer. (2020) Mol. Cell. Biochem.. Pubmed Mol. Cell. Biochem.
Zheng J, Zhu JL, Zhang Y, Zhang H, Yang Y, Tang DR and Sun J. PGK1 inhibitor CBR-470-1 protects neuronal cells from MPP+. (2020) Aging (Albany NY). 12, 13388-13399 Pubmed Aging (Albany NY) PMC Article
He F, Ru X and Wen T. NRF2, a Transcription Factor for Stress Response and Beyond. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci PMC Article
Hyun DH. Insights into the New Cancer Therapy through Redox Homeostasis and Metabolic Shifts. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel)
Mitra AK, Kumar H, Ramakrishnan V, Chen L, Baughn L, Kumar S, Rajkumar SV and Van Ness BG. In vitro and ex vivo gene expression profiling reveals differential kinetic response of HSPs and UPR genes is associated with PI resistance in multiple myeloma. (2020) Blood Cancer J. 10, 78 Pubmed Blood Cancer J
Li ZZ, Zhang ZW, Wang H, Chen YQ, Zhou XF, Duan LS, Wang XX, Xu F and Guo JR. Autologous transfusion of "old" red blood cells-induced M2 macrophage polarization through IL-10-Nrf2-HO-1 signaling complexes. (2020) Adv Clin Exp Med. 29, 833-840 Pubmed Adv Clin Exp Med
Zhang L, Chu W, Zheng L, Li J, Ren Y, Xue L, Duan W, Wang Q and Li H. Zinc oxide nanoparticles from Cyperus rotundus attenuates diabetic retinopathy by inhibiting NLRP3 inflammasome activation in STZ-induced diabetic rats. (2020) J. Biochem. Mol. Toxicol.. e22583 Pubmed J. Biochem. Mol. Toxicol.
Geng L, Xia Z, Yuan L, Li C, Zhang M, Du Y, Wei L and Bi H. Effects of β-HgS on cell viability and intracellular oxidative stress in PC-12 cells. (2020) Metallomics. Pubmed Metallomics
Moscat J and Diaz-Meco MT. The interplay between PRKCI/PKCλ/ι, SQSTM1/p62, and autophagy orchestrates the oxidative metabolic response that drives liver cancer. (2020) Autophagy. 1-3 Pubmed Autophagy
Estfanous RS, Elseady WS, Kabel AM and Abd Ellatif RA. Amelioration of Cisplatin-Induced Ototoxicity in Rats by L-arginine: The Role of Nitric Oxide, Transforming Growth Factor Beta 1 and Nrf2/HO-1 Pathway. (2020) Asian Pac. J. Cancer Prev.. 21, 2155-2162 Pubmed Asian Pac. J. Cancer Prev.
Sun X, Wang Y, Ji K, Liu Y, Kong Y, Nie S, Li N, Hao J, Xie Y, Xu C, Du L and Liu Q. NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest. (2020) Nucleic Acids Res.. Pubmed Nucleic Acids Res.
Karna KK, Soni KK, You JH, Choi NY, Kim HK, Kim CY, Lee SW, Shin YS and Park JK. MOTILIPERM Ameliorates Immobilization Stress-Induced Testicular Dysfunction via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway in SD Rats. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci PMC Article
Gandhi M and Nair S. New vistas in malignant mesothelioma: MicroRNA architecture and NRF2/MAPK signal transduction. (2020) Life Sci.. 257, 118123 Pubmed Life Sci.
Huang W, Shi G, Yong Z, Li J, Qiu J, Cao Y, Zhao Y and Yuan L. Downregulation of RKIP promotes radioresistance of nasopharyngeal carcinoma by activating NRF2/NQO1 axis via downregulating miR-450b-5p. (2020) Cell Death Dis. 11, 504 Pubmed Cell Death Dis PMC Article
Balan M and Pal S. Correction: A novel CXCR3-B chemokine receptor-induced growth-inhibitory signal in cancer cells is mediated through the regulation of Bach-1 protein and Nrf2 protein nuclear translocation. (2020) J. Biol. Chem.. 295, 10509 Pubmed J. Biol. Chem. PMC Article
Song HC, Chen Y, Chen Y, Park J, Zheng M, Surh YJ, Kim UH, Park JW, Yu R, Chung HT and Joe Y. GSK-3β inhibition by curcumin mitigates amyloidogenesis via TFEB activation and anti-oxidative activity in human neuroblastoma cells. (2020) Free Radic. Res.. 1-13 Pubmed Free Radic. Res.
Song H, Xu T, Feng X, Lai Y, Yang Y, Zheng H, He X, Wei G, Liao W, Liao Y, Zhong L and Bin J. Itaconate prevents abdominal aortic aneurysm formation through inhibiting inflammation via activation of Nrf2. (2020) EBioMedicine. 57, 102832 Pubmed EBioMedicine PMC Article
Farkhondeh T, Folgado SL, Pourbagher-Shahri AM, Ashrafizadeh M and Samarghandian S. The therapeutic effect of resveratrol: Focusing on the Nrf2 signaling pathway. (2020) Biomed. Pharmacother.. 127, 110234 Pubmed Biomed. Pharmacother.
Abdel-Wahab BA, Alkahtani SA and Elagab EAM. Tadalafil alleviates cisplatin-induced reproductive toxicity through the activation of the Nrf2/HO-1 pathway and the inhibition of oxidative stress and apoptosis in male rats. (2020) Reprod. Toxicol.. 96, 165-174 Pubmed Reprod. Toxicol.
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Zhang X, Li T, Gong ES and Liu RH. Antiproliferative Activity of Ursolic Acid in MDA-MB-231 Human Breast Cancer Cells through Nrf2 Pathway Regulation. (2020) J. Agric. Food Chem.. 68, 7404-7415 Pubmed J. Agric. Food Chem.
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