English: Graph of Nrf2 publications (pubmed se...

English: Graph of Nrf2 publications (pubmed search) by year (Photo credit: Wikipedia)

There are currently over 2300 articles (peer reviewed clinical reviews and studies) on Pubmed.gov on the topic of NRF2 Activation. There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to Pubmed.gov and type in the name of their product. Pubmed is a website operated by the National Institute of Health (NIH).  PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources. Last 200 NRF-2 Studies published on Pubmed
Acito M, Bartolini D, Ceccarini MR, Russo C, Vannini S, Dominici L, Codini M, Villarini M, Galli F, Beccari T and Moretti M. Imbalance in the antioxidant defence system and pro-genotoxic status induced by high glucose concentrations: In vitro testing in human liver cells. (2020) Toxicol In Vitro. 69, 105001 Pubmed Toxicol In Vitro
Zhang F, Liu Z, He X, Li Z, Shi B and Cai F. β-Sitosterol-loaded solid lipid nanoparticles ameliorate complete Freund's adjuvant-induced arthritis in rats: involvement of NF-кB and HO-1/Nrf-2 pathway. (2020) Drug Deliv. 27, 1329-1341 Pubmed Drug Deliv PMC Article
Reyes-Soto CY, Rangel-López E, Galván-Arzate S, Colín-González AL, Silva-Palacios A, Zazueta C, Pedraza-Chaverri J, Ramírez J, Chavarria A, Túnez I, Ke T, Aschner M and Santamaría A. S-Allylcysteine Protects Against Excitotoxic Damage in Rat Cortical Slices Via Reduction of Oxidative Damage, Activation of Nrf2/ARE Binding, and BDNF Preservation. (2020) Neurotox Res. 38, 929-940 Pubmed Neurotox Res
Recalde MD, Miguel CA, Noya-Riobó MV, González SL, Villar MJ and Coronel MF. Resveratrol exerts anti-oxidant and anti-inflammatory actions and prevents oxaliplatin-induced mechanical and thermal allodynia. (2020) Brain Res. 1748, 147079 Pubmed Brain Res
Liu RM, Xu P, Chen Q, Feng SL and Xie Y. A multiple-targets alkaloid nuciferine overcomes paclitaxel-induced drug resistance in vitro and in vivo. (2020) Phytomedicine. 79, 153342 Pubmed Phytomedicine
Li M, Liu P, Xue Y, Liang Y, Shi J, Han X, Zhang J, Chu X and Chu L. Tannic acid attenuates hepatic oxidative stress, apoptosis and inflammation by activating the Keap1‑Nrf2/ARE signaling pathway in arsenic trioxide‑toxicated rats. (2020) Oncol Rep. 44, 2306-2316 Pubmed Oncol Rep
Martínez MA, Ares I, Martínez M, Lopez-Torres B, Rodríguez JL, Maximiliano JE, Martínez-Larrañaga MR, Anadón A, Rosa JM and Cueto M. Protective effects of culture extracts (CB08035-SCA and CB08035-SYP) from Marinobacter hydrocarbonoclasticus (strain CB08035) against oxidant-induced stress in human colon carcinoma Caco-2 cells. (2020) Food Chem Toxicol. 145, 111671 Pubmed Food Chem Toxicol
Wang H, Dou S, Zhu J, Shao Z, Wang C and Cheng B. Ghrelin mitigates MPP-induced cytotoxicity: Involvement of ERK1/2-mediated Nrf2/HO-1 and endoplasmic reticulum stress PERK signaling pathway. (2020) Peptides. 133, 170374 Pubmed Peptides
Romualdo GR, Prata GB, da Silva TC, Evangelista AF, Reis RM, Vinken M, Moreno FS, Cogliati B and Barbisan LF. The combination of coffee compounds attenuates early fibrosis-associated hepatocarcinogenesis in mice: involvement of miRNA profile modulation. (2020) J Nutr Biochem. 85, 108479 Pubmed J Nutr Biochem
Rong Y, Huang L, Yi K, Chen H, Liu S, Zhang W, Yuan C, Song X and Wang F. Co-administration of sulforaphane and doxorubicin attenuates breast cancer growth by preventing the accumulation of myeloid-derived suppressor cells. (2020) Cancer Lett. 493, 189-196 Pubmed Cancer Lett
Imaoka T, Yang J, Wang L, McDonald MG, Afsharinejad Z, Bammler TK, Van Ness K, Yeung CK, Rettie AE, Himmelfarb J and Kelly EJ. Microphysiological system modeling of ochratoxin A-associated nephrotoxicity. (2020) Toxicology. 444, 152582 Pubmed Toxicology PMC Article
Singh A, Daemen A, Nickles D, Jeon SM, Foreman O, Sudini K, Gnad F, Lajoie S, Gour N, Mitzner W, Chatterjee S, Choi EJ, Ravishankar B, Rappaport A, Patil NS, McCleland M, Johnson L, Acquaah-Mensah GK, Gabrielson E, Biswal S and Hatzivassiliou G. NRF2 activation promotes aggressive lung cancer and associates with poor clinical outcomes. (2020) Clin Cancer Res. Pubmed Clin Cancer Res
Kassab RB, Lokman MS, Daabo HMA, Gaber DA, Habotta OA, Hafez MM, Zhery AS, Moneim AEA and Fouda MS. Ferulic acid influences Nrf2 activation to restore testicular tissue from cadmium-induced oxidative challenge, inflammation, and apoptosis in rats. (2020) J Food Biochem. e13505 Pubmed J Food Biochem
Mykhailenko O, Korinek M, Ivanauskas L, Bezruk I, Myhal A, Petrikaitė V, El-Shazly M, Lin GH, Lin CY, Yen CH, Chen BH, Georgiyants V and Hwang TL. Qualitative and Quantitative Analysis of Ukrainian Species: A Fresh Look on Their Antioxidant Content and Biological Activities. (2020) Molecules. 25, Pubmed Molecules
L Suraweera T, Rupasinghe HPV, Dellaire G and Xu Z. Regulation of Nrf2/ARE Pathway by Dietary Flavonoids: A Friend or Foe for Cancer Management?. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel)
Mele L, Del Vecchio V, Marampon F, Regad T, Wagner S, Mosca L, Bimonte S, Giudice A, Liccardo D, Prisco C, Schwerdtfeger M, La Noce M, Tirino V, Caraglia M, Papaccio G, Desiderio V and Barbieri A. β-AR blockade potentiates MEK1/2 inhibitor effect on HNSCC by regulating the Nrf2-mediated defense mechanism. (2020) Cell Death Dis. 11, 850 Pubmed Cell Death Dis PMC Article
Mostafa AF, Elalfy MM, Shata A and Elhadidy MG. Prophylactic effect of aquatic extract of stevia on acetic acid induced-ulcerative colitis in male rats: a possible role of Nrf2 and PPARγ. (2020) J Basic Clin Physiol Pharmacol. Pubmed J Basic Clin Physiol Pharmacol
Wan S, Pan Q, Yang G, Kuang J and Luo S. Role of CYP4F2 as a novel biomarker regulating malignant phenotypes of liver cancer cells via the Nrf2 signaling axis. (2020) Oncol Lett. 20, 13 Pubmed Oncol Lett PMC Article
Thakur S, Sarkar B, Dhiman M and Mantha AK. Organophosphate-pesticides induced survival mechanisms and APE1-mediated Nrf2 regulation in non-small-cell lung cancer cells. (2020) J Biochem Mol Toxicol. e22640 Pubmed J Biochem Mol Toxicol
Li P, Hu J, Shi B and Tie J. Baicalein enhanced cisplatin sensitivity of gastric cancer cells by inducing cell apoptosis and autophagy via Akt/mTOR and Nrf2/Keap 1 pathway. (2020) Biochem Biophys Res Commun. 531, 320-327 Pubmed Biochem Biophys Res Commun
Qiu L, Ma Z, Li X, Deng Y, Duan G, Zhao L, Xu X, Xiao L, Liu H, Zhu Z and Chen H. DJ-1 is involved in the multidrug resistance of SGC7901 gastric cancer cells through PTEN/PI3K/Akt/Nrf2 pathway. (2020) Acta Biochim Biophys Sin (Shanghai). Pubmed Acta Biochim Biophys Sin (Shanghai)
Piotrowska M, Swierczynski M, Fichna J and Piechota-Polanczyk A. The Nrf2 in the pathophysiology of the intestine: molecular mechanisms and therapeutic implications for inflammatory bowel diseases. (2020) Pharmacol Res. 105243 Pubmed Pharmacol Res
DeBlasi JM and DeNicola GM. Dissecting the Crosstalk between NRF2 Signaling and Metabolic Processes in Cancer. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel)
Di Sotto A, Mancinelli R, Gullì M, Eufemi M, Mammola CL, Mazzanti G and Di Giacomo S. Chemopreventive Potential of Caryophyllane Sesquiterpenes: An Overview of Preliminary Evidence. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel)
Mita-Mendoza NK, Magallon-Tejada A, Parmar P, Furtado R, Aldrich M, Saidi A, Taylor T, Smith J, Seydel K and Daily JP. Dimethyl fumarate reduces TNF and Plasmodium falciparum induced brain endothelium activation in vitro. (2020) Malar J. 19, 376 Pubmed Malar J PMC Article
Yardim A, Kandemir FM, Ozdemir S, Kucukler S, Comakli S, Gur C and Celik H. Quercetin provides protection against the peripheral nerve damage caused by vincristine in rats by suppressing caspase 3, NF-κB, ATF-6 pathways and activating Nrf2, Akt pathways. (2020) Neurotoxicology. 81, 137-146 Pubmed Neurotoxicology
Xie LW, Cai S, Zhao TS, Li M and Tian Y. Green tea derivative (-)-epigallocatechin-3-gallate (EGCG) confers protection against ionizing radiation-induced intestinal epithelial cell death both in vitro and in vivo. (2020) Free Radic Biol Med. 161, 175-186 Pubmed Free Radic Biol Med
Abusarah J, Cui Y, El-Hachem N, El-Kadiry AE, Hammond-Martel I, Wurtele H, Beaudry A, Raynal NJ, Robert F, Pelletier J, Jankovic M, Mercier F, Kamyabiazar S, Annabi B and Rafei M. TACIMA-218: A NOVEL PRO-OXIDANT AGENT EXHIBITING SELECTIVE ANTI-TUMORAL ACTIVITY. (2020) Mol Cancer Ther. Pubmed Mol Cancer Ther
Yardım A, Kucukler S, Özdemir S, Çomaklı S, Caglayan C, Kandemir FM and Çelik H. Silymarin alleviates docetaxel-induced central and peripheral neurotoxicity by reducing oxidative stress, inflammation and apoptosis in rats. (2020) Gene. 145239 Pubmed Gene
Heft Neal ME, Bhangale AD, Birkeland AC, McHugh JB, Shuman AG, Rosko AJ, Swiecicki PL, Spector ME and Brenner JC. Prognostic Significance of Oxidation Pathway Mutations in Recurrent Laryngeal Squamous Cell Carcinoma. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel)
Khan H, Tundis R, Ullah H, Aschner M, Belwal T, Mirzaei H and Akkol EK. Flavonoids targeting NRF2 in neurodegenerative disorders. (2020) Food Chem Toxicol. 146, 111817 Pubmed Food Chem Toxicol
Abouzed TK, Beltagy ER, Kahilo KA and Ibrahim WM. Molecular changes associated with the anticancer effect of sulforaphane against Ehrlich solid tumour in mice. (2020) J Biochem Mol Toxicol. e22655 Pubmed J Biochem Mol Toxicol
Guo H, Wang Y and Liu D. Silibinin ameliorats HO-induced cell apoptosis and oxidative stress response by activating Nrf2 signaling in trophoblast cells. (2020) Acta Histochem. 122, 151620 Pubmed Acta Histochem
Wang T, Jian Z, Baskys A, Yang J, Li J, Guo H, Hei Y, Xian P, He Z, Li Z, Li N and Long Q. MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system. (2020) Biomaterials. 257, 120264 Pubmed Biomaterials
Song CH, Kim N, Hee Nam R, In Choi S, Hee Son J, Eun Yu J, Shin E, Lee HN, Kim DH and Surh YJ. 17β-Estradiol strongly inhibits azoxymethane/dextran sulfate sodium-induced colorectal cancer development in Nrf2 knockout male mice. (2020) Biochem Pharmacol. 182, 114279 Pubmed Biochem Pharmacol
Sári Z, Mikó E, Kovács T, Boratkó A, Ujlaki G, Jankó L, Kiss B, Uray K and Bai P. Indoxylsulfate, a Metabolite of the Microbiome, Has Cytostatic Effects in Breast Cancer via Activation of AHR and PXR Receptors and Induction of Oxidative Stress. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel)
Hu ST, Li XY, Chen H, Xu LH and Fang JP. [Knockdown of ALAS2 Affects Erythroid Differentiation by Down-regulating Mitophagy Receptor BNIP3L]. (2020) Zhongguo Shi Yan Xue Ye Xue Za Zhi. 28, 1710-1717 Pubmed Zhongguo Shi Yan Xue Ye Xue Za Zhi
Cao L, Hong W, Cai P, Xu C, Bai X, Zhao Z, Huang M and Jin J. Cryptotanshinone strengthens the effect of gefitinib against non-small cell lung cancer through inhibiting transketolase. (2020) Eur J Pharmacol. 173647 Pubmed Eur J Pharmacol
Bose C, Alves I, Singh P, Palade PT, Carvalho E, Børsheim E, Jun SR, Cheema A, Boerma M, Awasthi S and Singh SP. Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling. (2020) Aging Cell. e13261 Pubmed Aging Cell
Mehranfard N, Yazdi A, Rafiei A, Shakerin Z and Ghasemi M. Honey protects against chronic unpredictable mild stress induced- intestinal barrier disintegration and hepatic inflammation. (2020) Mol Biol Rep. Pubmed Mol Biol Rep
Ambrosio L, Argenziano M, Cucci MA, Grattarola M, de Graaf IAM, Dianzani C, Barrera G, Sánchez Nieves J, Gomez R, Cavalli R and Pizzimenti S. Carbosilane Dendrimers Loaded with siRNA Targeting Nrf2 as a Tool to Overcome Cisplatin Chemoresistance in Bladder Cancer Cells. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel)
Staples S, Wall SB, Li R and Tipple TE. Selenium-independent antioxidant and anti-inflammatory effects of thioredoxin reductase inhibition in alveolar macrophages. (2020) Life Sci. 259, 118285 Pubmed Life Sci
Galicia-Moreno M, Lucano-Landeros S, Monroy-Ramirez HC, Silva-Gomez J, Gutierrez-Cuevas J, Santos A and Armendariz-Borunda J. Roles of Nrf2 in Liver Diseases: Molecular, Pharmacological, and Epigenetic Aspects. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel)
Sampath C, Srinivasan S, Freeman ML and Gangula PR. Inhibition of GSK-3β restores delayed gastric emptying in obesity-induced diabetic female mice. (2020) Am J Physiol Gastrointest Liver Physiol. 319, G481-G493 Pubmed Am J Physiol Gastrointest Liver Physiol
Licznerska B, Szaefer H and Krajka-Kuźniak V. R-sulforaphane modulates the expression profile of AhR, ERα, Nrf2, NQO1, and GSTP in human breast cell lines. (2020) Mol Cell Biochem. Pubmed Mol Cell Biochem
Albrakati A. Aged garlic extract rescues ethephon-induced kidney damage by modulating oxidative stress, apoptosis, inflammation, and histopathological changes in rats. (2020) Environ Sci Pollut Res Int. Pubmed Environ Sci Pollut Res Int
Olagnier D, Farahani E, Thyrsted J, Blay-Cadanet J, Herengt A, Idorn M, Hait A, Hernaez B, Knudsen A, Iversen MB, Schilling M, Jørgensen SE, Thomsen M, Reinert LS, Lappe M, Hoang HD, Gilchrist VH, Hansen AL, Ottosen R, Nielsen CG, Møller C, van der Horst D, Peri S, Balachandran S, Huang J, Jakobsen M, Svenningsen EB, Poulsen TB, Bartsch L, Thielke AL, Luo Y, Alain T, Rehwinkel J, Alcamí A, Hiscott J, Mogensen TH, Paludan SR and Holm CK. SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate. (2020) Nat Commun. 11, 4938 Pubmed Nat Commun PMC Article
Li YJ, Shimizu T, Shinkai Y, Ihara T, Sugamata M, Kato K, Kobayashi M, Hirata Y, Inagaki H, Uzuki M, Akimoto T, Umezawa M, Takeda K, Azuma A, Yamamoto M and Kawada T. Nrf2 Lowers the Risk of Lung Injury via Modulating the Airway Innate Immune Response Induced by Diesel Exhaust in Mice. (2020) Biomedicines. 8, Pubmed Biomedicines
Deville SS, Luft S, Kaufmann M and Cordes N. Keap1 inhibition sensitizes head and neck squamous cell carcinoma cells to ionizing radiation via impaired non-homologous end joining and induced autophagy. (2020) Cell Death Dis. 11, 887 Pubmed Cell Death Dis PMC Article
Ishida N, Aoki Y, Katsuoka F, Nishijima I, Nobukuni T, Anzawa H, Bin L, Tsuda M, Kumada K, Kudo H, Terakawa T, Otsuki A, Kinoshita K, Yamashita R, Minegishi N and Yamamoto M. Landscape of electrophilic and inflammatory stress-mediated gene regulation in human lymphoblastoid cell lines. (2020) Free Radic Biol Med. 161, 71-83 Pubmed Free Radic Biol Med
Chao X, Qian H, Wang S, Fulte S and Ding WX. Autophagy and liver cancer. (2020) Clin Mol Hepatol. 26, 606-617 Pubmed Clin Mol Hepatol
Ziv E, Zhang Y, Kelly L, Nikolovski I, Boas FE, Erinjeri JP, Cai L, Petre EN, Brody LA, Covey AM, Getrajdman G, Harding JJ, Sofocleous C, Abou-Alfa GK, Solomon SB, Brown KT and Yarmohammadi H. NRF2 Dysregulation in Hepatocellular Carcinoma and Ischemia: A Cohort Study and Laboratory Investigation. (2020) Radiology. 297, 225-234 Pubmed Radiology PMC Article
Sim H, Choo S, Kim J, Baek MC and Bae JS. Fisetin Suppresses Pulmonary Inflammatory Responses through Heme Oxygenase-1 Mediated Downregulation of Inducible Nitric Oxide Synthase. (2020) J Med Food. Pubmed J Med Food
Liu Z, Wang J, Zhang Y, Wu D, Li S, Jiang A, Du C and Xie G. Pterostilbene Exerts Hepatoprotective Effects through Ameliorating LPS/D-Gal-Induced Acute Liver Injury in Mice. (2020) Inflammation. Pubmed Inflammation
Jiang Y, Zhang K, Yu Y, Wang Y, Lian N, Xie K and Yu Y. Molecular hydrogen alleviates brain injury and cognitive impairment in a chronic sequelae model of murine polymicrobial sepsis. (2020) Exp Brain Res. Pubmed Exp Brain Res
He L, Zhang T, Sun W, Qin Y, Wang Z, Dong W and Zhang H. The DPP-IV inhibitor saxagliptin promotes the migration and invasion of papillary thyroid carcinoma cells via the NRF2/HO1 pathway. (2020) Med Oncol. 37, 97 Pubmed Med Oncol
Talebi M, Talebi M, Farkhondeh T and Samarghandian S. Biological and therapeutic activities of thymoquinone: Focus on the Nrf2 signaling pathway. (2020) Phytother Res. Pubmed Phytother Res
Orrù C, Giordano S and Columbano A. Nrf2 in Neoplastic and Non-Neoplastic Liver Diseases. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel)
Liu Z and Sun X. A Critical Review of the Abilities, Determinants, and Possible Molecular Mechanisms of Seaweed Polysaccharides Antioxidants. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci
Lou JS, Zhao LP, Huang ZH, Chen XY, Xu JT, Tai WC, Tsim KWK, Chen YT and Xie T. Ginkgetin derived from Ginkgo biloba leaves enhances the therapeutic effect of cisplatin via ferroptosis-mediated disruption of the Nrf2/HO-1 axis in EGFR wild-type non-small-cell lung cancer. (2020) Phytomedicine. 80, 153370 Pubmed Phytomedicine
Song MY, Lee DY and Kim EH. Anti-inflammatory and anti-oxidative effect of Korean propolis on Helicobacter pylori-induced gastric damage in vitro. (2020) J Microbiol. 58, 878-885 Pubmed J Microbiol
Du J, Fu L, Ji F, Wang C, Liu S and Qiu X. FosB recruits KAT5 to potentiate the growth and metastasis of papillary thyroid cancer in a DPP4-dependent manner. (2020) Life Sci. 259, 118374 Pubmed Life Sci
Zhang J, Liu L, Li F, Wang Z and Zhao J. Treatment with catalpol protects against cisplatin-induced renal injury through Nrf2 and NF-κB signaling pathways. (2020) Exp Ther Med. 20, 3025-3032 Pubmed Exp Ther Med PMC Article
Marinello PC, Panis C, Silva TNX, Binato R, Abdelhay E, Rodrigues JA, L Mencalha A, Lopes NMD, Borges FH, Luiz RC, Cecchini R and Cecchini AL. Oxidative stress and TGF-β1 induction by metformin in MCF-7 and MDA-MB-231 human breast cancer cells are accompanied with the downregulation of genes related to cell proliferation, invasion and metastasis. (2020) Pathol Res Pract. 216, 153135 Pubmed Pathol Res Pract
Siswanto FM, Oguro A, Arase S and Imaoka S. WDR23 regulates the expression of Nrf2-driven drug-metabolizing enzymes. (2020) Drug Metab Pharmacokinet. 35, 441-455 Pubmed Drug Metab Pharmacokinet
Gagliardi M, Saverio V, Monzani R, Ferrari E, Piacentini M and Corazzari M. Ferroptosis: a new unexpected chance to treat metastatic melanoma?. (2020) Cell Cycle. 19, 2411-2425 Pubmed Cell Cycle PMC Article
Wu C, Zhang H, Lin X, Zeng Y, Zhang Y, Ma X, Xue Y and Guan M. Role of PDK4 in insulin signaling pathway in periadrenal adipose tissue of pheochromocytoma patients. (2020) Endocr Relat Cancer. 27, 583-589 Pubmed Endocr Relat Cancer
Martinez R, Huang W, Samadani R, Mackowiak B, Centola G, Chen L, Conlon IL, Hom K, Kane MA, Fletcher S and Shapiro P. Mechanistic analysis of an ERK2-interacting compound that inhibits mutant-BRAF expressing melanoma cells by inducing oxidative stress. (2020) J Pharmacol Exp Ther. Pubmed J Pharmacol Exp Ther
Baird L, Suzuki T, Takahashi Y, Hishinuma E, Saigusa D and Yamamoto M. Geldanamycin-Derived HSP90 Inhibitors Are Synthetic Lethal with NRF2. (2020) Mol Cell Biol. 40, Pubmed Mol Cell Biol
Sun Q, Ye Z, Qin Y, Fan G, Ji S, Zhuo Q, Xu W, Liu W, Hu Q, Liu M, Zhang Z, Xu X and Yu X. Oncogenic function of TRIM2 in pancreatic cancer by activating ROS-related NRF2/ITGB7/FAK axis. (2020) Oncogene. 39, 6572-6588 Pubmed Oncogene
Zhu X, Tian X, Yang M, Yu Y, Zhou Y, Gao Y, Zhang L, Li Z, Xiao Y, Moses RE, Li X and Zhang B. Procyanidin B2 Promotes Intestinal Injury Repair and Attenuates Colitis-Associated Tumorigenesis Suppression of Oxidative Stress in Mice. (2020) Antioxid Redox Signal. Pubmed Antioxid Redox Signal
Li X, Liu X, Zhang Y, Zhang Y, Liu S, Zhang N, Li Y and Wang D. Protective effect of Gloeostereum incarnatum on ulcerative colitis via modulation of Nrf2/NF‑κB signaling in C57BL/6 mice. (2020) Mol Med Rep. 22, 3418-3428 Pubmed Mol Med Rep PMC Article
Barroso E, Rodríguez-Rodríguez R, Zarei M, Pizarro-Degado J, Planavila A, Palomer X, Villarroya F and Vázquez-Carrera M. SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2. (2020) Cell Commun Signal. 18, 147 Pubmed Cell Commun Signal PMC Article
Jessen C, Kreß JKC, Baluapuri A, Hufnagel A, Schmitz W, Kneitz S, Roth S, Marquardt A, Appenzeller S, Ade CP, Glutsch V, Wobser M, Friedmann-Angeli JP, Mosteo L, Goding CR, Schilling B, Geissinger E, Wolf E and Meierjohann S. The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression. (2020) Oncogene. Pubmed Oncogene
Khaled S, Makled MN and Nader MA. Tiron protects against nicotine-induced lung and liver injury through antioxidant and anti-inflammatory actions in rats in vivo. (2020) Life Sci. 260, 118426 Pubmed Life Sci
Bhattacharjee S and Dashwood RH. Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel) PMC Article
Cai LJ, Tu L, Huang XM, Huang J, Qiu N, Xie GH, Liao JX, Du W, Zhang YY and Tian JY. LncRNA MALAT1 facilitates inflammasome activation via epigenetic suppression of Nrf2 in Parkinson's disease. (2020) Mol Brain. 13, 130 Pubmed Mol Brain PMC Article
Yang L, Zhou X, Sun J, Lei Q, Wang Q, Pan D, Ding M and Ding Y. Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer. (2020) Cell Death Dis. 11, 766 Pubmed Cell Death Dis PMC Article
Kou X, Zhu J, Xie X, Hao M and Zhao Y. The protective effect of glycyrrhizin on hepatic ischemia-reperfusion injury in rats and possible related signal pathway. (2020) Iran J Basic Med Sci. 23, 1232-1238 Pubmed Iran J Basic Med Sci PMC Article
De Nuccio C, Bernardo A, Troiano C, Brignone MS, Falchi M, Greco A, Rosini M, Basagni F, Lanni C, Serafini MM, Minghetti L and Visentin S. NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci
Yan Z, Qi W, Zhan J, Lin Z, Lin J, Xue X, Pan X and Zhou Y. Activating Nrf2 signalling alleviates osteoarthritis development by inhibiting inflammasome activation. (2020) J Cell Mol Med. Pubmed J Cell Mol Med
Xu M, Jiang P, Sun H, Yuan X, Gao S, Guo J, Zhao C, Hu X, Liu X and Fu Y. Dimethyl itaconate protects against lipopolysaccharide-induced endometritis by inhibition of TLR4/NF-κB and activation of Nrf2/HO-1 signaling pathway in mice. (2020) Iran J Basic Med Sci. 23, 1239-1244 Pubmed Iran J Basic Med Sci PMC Article
Seiwert N, Wecklein S, Demuth P, Hasselwander S, Kemper TA, Schwerdtle T, Brunner T and Fahrer J. Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron. (2020) Cell Death Dis. 11, 787 Pubmed Cell Death Dis PMC Article
Roy NK, Murphy A and Costa M. Arsenic Methyltransferase and Methylation of Inorganic Arsenic. (2020) Biomolecules. 10, Pubmed Biomolecules PMC Article
Fabrizio FP, Mazza T, Castellana S, Sparaneo A and Muscarella LA. Epigenetic Scanning of CpG Sites Uncovers New Molecular-Driven Patterns in Lung Adeno and Squamous Cell Carcinomas. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel) PMC Article
Deland K, Starr BF, Mercer JS, Byemerwa J, Crabtree DM, Williams NT, Luo L, Ma Y, Chen M, Becher OJ and Kirsch DG. Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models. (2020) J Clin Invest. Pubmed J Clin Invest
Kobayashi A. Roles of NRF3 in the Hallmarks of Cancer: Proteasomal Inactivation of Tumor Suppressors. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel) PMC Article
Payandeh Z, Pirpour Tazehkand A, Barati G, Pouremamali F, Kahroba H, Baradaran B and Samadi N. Role of Nrf2 and mitochondria in cancer stem cells; in carcinogenesis, tumor progression, and chemoresistance. (2020) Biochimie. 179, 32-45 Pubmed Biochimie
Wang L, Chen Y, Mi Y, Qiao J, Jin H, Li J, Lu Z, Wang Q and Zou Z. ATF2 inhibits ani-tumor effects of BET inhibitor in a negative feedback manner by attenuating ferroptosis. (2020) Biochem Biophys Res Commun. Pubmed Biochem Biophys Res Commun
Barakat LAA, Barakat N, Zakaria MM and Khirallah SM. Protective role of zinc oxide nanoparticles in kidney injury induced by cisplatin in rats. (2020) Life Sci. 262, 118503 Pubmed Life Sci
Li Z, Guo H, Li J, Ma T, Zhou S, Zhang Z, Miao L and Cai L. Sulforaphane prevents type 2 diabetes-induced nephropathy via AMPK-mediated activation of lipid metabolic pathways and Nrf2 antioxidative function. (2020) Clin Sci (Lond). 134, 2469-2487 Pubmed Clin Sci (Lond)
Wang Y, Cui X, Lin Q, Cai J, Tang L and Liang Y. Active Peptide KF-8 from Rice Bran Attenuates Oxidative Stress in a Mouse Model of Aging Induced by d-Galactose. (2020) J Agric Food Chem. Pubmed J Agric Food Chem
Ling L, Tong J and Zeng L. [Paeoniflorin Improves Acute Lung Injury in Sepsis by Activating Nrf2/Keap1 Signaling Pathway]. (2020) Sichuan Da Xue Xue Bao Yi Xue Ban. 51, 664-669 Pubmed Sichuan Da Xue Xue Bao Yi Xue Ban
Elsherbiny NM, Eisa NH, El-Sherbiny M and Said E. Chemo-preventive effect of crocin against experimentally-induced hepatocarcinogenesis via regulation of apoptotic and Nrf2 signaling pathways. (2020) Environ Toxicol Pharmacol. 80, 103494 Pubmed Environ Toxicol Pharmacol
Cai L, Jin X, Zhang J, Li L and Zhao J. Metformin suppresses Nrf2-mediated chemoresistance in hepatocellular carcinoma cells by increasing glycolysis. (2020) Aging (Albany NY). 12, 17582-17600 Pubmed Aging (Albany NY) PMC Article
Schmidlin CJ, Rojo de la Vega M, Perer J, Zhang DD and Wondrak GT. Activation of NRF2 by topical apocarotenoid treatment mitigates radiation-induced dermatitis. (2020) Redox Biol. 37, 101714 Pubmed Redox Biol PMC Article
Liang Y, Zheng B, Li J, Shi J, Chu L, Han X, Chu X, Zhang X and Zhang J. Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis. (2020) Biomed Pharmacother. 131, 110713 Pubmed Biomed Pharmacother
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