There are currently over 2300 articles (peer reviewed clinical reviews and studies) on Pubmed.gov on the topic of NRF2 Activation. There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to Pubmed.gov and type in the name of their product. Pubmed is a website operated by the National Institute of Health (NIH). PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources. Last 200 NRF-2 Studies published on Pubmed
Puerarin induces apoptosis in prostate cancer cells via inactivation of the Keap1/Nrf2/ARE signaling pathway. (2021) Bioengineered. 12, 402-413 Pubmed Bioengineered
Conflicting metabolic alterations in cancer stem cells and regulation by the stromal niche. (2021) Regen Ther. 17, 8-12 Pubmed Regen Ther PMC Article
LC-MS characterized methanolic extract of zanthoxylum armatum possess anti-breast cancer activity through Nrf2-Keap1 pathway: An in-silico, in-vitro and in-vivo evaluation. (2021) J Ethnopharmacol. 269, 113758 Pubmed J Ethnopharmacol
Ex vivo fecal fermentation of human ileal fluid collected after raspberry consumption modifies (poly)phenolics and modulates genoprotective effects in colonic epithelial cells. (2021) Redox Biol. 40, 101862 Pubmed Redox Biol PMC Article
Interaction of Nrf2 with dimeric STAT3 induces IL-23 expression: Implications for breast cancer progression. (2021) Cancer Lett. 500, 147-160 Pubmed Cancer Lett
Nrf2‑Keap1‑ARE‑NQO1 signaling attenuates hyperoxia‑induced lung cell injury by inhibiting apoptosis. (2021) Mol Med Rep. 23, 1 Pubmed Mol Med Rep
Melatonin reverses cognitive deficits in streptozotocin-induced type 1 diabetes in the rat through attenuation of oxidative stress and inflammation. (2021) J Chem Neuroanat. 112, 101902 Pubmed J Chem Neuroanat
Apoptotic activities of brusatol in human non-small cell lung cancer cells: Involvement of ROS-mediated mitochondrial-dependent pathway and inhibition of Nrf2-mediated antioxidant response. (2021) Toxicology. 451, 152680 Pubmed Toxicology
Chondrocyte ferroptosis contribute to the progression of osteoarthritis. (2021) J Orthop Translat. 27, 33-43 Pubmed J Orthop Translat PMC Article
Carnosic acid depends on glutathione to promote mitochondrial protection in methylglyoxal-exposed SH-SY5Y cells. (2021) Metab Brain Dis. 36, 471-481 Pubmed Metab Brain Dis
Schizandrin B attenuates hypoxia/reoxygenation injury in H9c2 cells by activating the AMPK/Nrf2 signaling pathway. (2021) Exp Ther Med. 21, 220 Pubmed Exp Ther Med PMC Article
LMTK2 regulates inflammation in lipopolysaccharide-stimulated BV2 cells. (2021) Exp Ther Med. 21, 219 Pubmed Exp Ther Med PMC Article
Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway. (2021) J Nutr Biochem. 89, 108573 Pubmed J Nutr Biochem
NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy. (2021) Cancers (Basel). 13, Pubmed Cancers (Basel)
Ginnalin A Binds to the Subpockets of Keap1 Kelch Domain To Activate the Nrf2-Regulated Antioxidant Defense System in SH-SY5Y Cells. (2021) ACS Chem Neurosci. Pubmed ACS Chem Neurosci
Redox changes in obesity, metabolic syndrome, and diabetes. (2021) Redox Biol. 101887 Pubmed Redox Biol
Dracomolphin A-E, new lignans from Dracocephalum moldavica. (2021) Fitoterapia. 150, 104841 Pubmed Fitoterapia
Nrf2: a main responsive element in cells to mycotoxin-induced toxicity. (2021) Arch Toxicol. Pubmed Arch Toxicol
N-Acetyl-Lysyltyrosylcysteine Amide, a Novel Systems Pharmacology Agent, Reduces Bronchopulmonary Dysplasia in Hyperoxic Neonatal Rat Pups. (2021) Free Radic Biol Med. Pubmed Free Radic Biol Med
Puerarin induces Nrf2 as a cytoprotective mechanism to prevent cadmium-induced autophagy inhibition and NLRP3 inflammasome activation in AML12 hepatic cells. (2021) J Inorg Biochem. 217, 111389 Pubmed J Inorg Biochem
Comparative metabolites profiling of Caryota mitis & Caryota urens via UPLC/MS and isolation of two novel in silico chemopreventive flavonoids. (2021) J Food Biochem. e13648 Pubmed J Food Biochem
polysaccharide inhibits high glucose-induced oxidative stress, inflammatory response, and apoptosis in RPE cells. (2021) J Recept Signal Transduct Res. 1-8 Pubmed J Recept Signal Transduct Res
Transcriptional control of the oxidative stress response and implications of using plant derived molecules for therapeutic interventions in cancer. (2021) Curr Med Chem. Pubmed Curr Med Chem
Induction of liver fibrosis by CCl4 mediates pathological alterations in the spleen and lymph nodes: The potential therapeutic role of propolis. (2021) Saudi J Biol Sci. 28, 1272-1282 Pubmed Saudi J Biol Sci PMC Article
Neuroprotective effect of apigenin against hypoxic-ischemic brain injury in neonatal rats activation of the PI3K/Akt/Nrf2 signaling pathway. (2021) Food Funct. Pubmed Food Funct
Dihydroactinidiolide regulates Nrf2/HO-1 expression and inhibits caspase-3/Bax pathway to protect SH-SY5Y human neuroblastoma cells from oxidative stress induced neuronal apoptosis. (2021) Neurotoxicology. Pubmed Neurotoxicology
Fucoxanthin inhibits lipopolysaccharide-induced inflammation and oxidative stress by activating nuclear factor E2-related factor 2 via the phosphatidylinositol 3-kinase/AKT pathway in macrophages. (2021) Eur J Nutr. Pubmed Eur J Nutr
Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multi-layered Protection against ROS. (2021) Hepatology. Pubmed Hepatology
New insights into the role of the Nrf2 signaling pathway in green tea catechin applications. (2021) Phytother Res. Pubmed Phytother Res
Targeting Nrf2 may reverse the drug resistance in ovarian cancer. (2021) Cancer Cell Int. 21, 116 Pubmed Cancer Cell Int PMC Article
Bariatric surgery can acutely modulate ER-stress and inflammation on subcutaneous adipose tissue in non-diabetic patients with obesity. (2021) Diabetol Metab Syndr. 13, 19 Pubmed Diabetol Metab Syndr PMC Article
Nrf2 Regulates Granuloma Formation and Macrophage Activation during Mycobacterium avium Infection via Mediating Nramp1 and HO-1 Expressions. (2021) mBio. 12, Pubmed mBio PMC Article
The antioxidant response in Barrett's tumorigenesis: A double-edged sword. (2021) Redox Biol. 41, 101894 Pubmed Redox Biol
Cardioprotective Effect of Linalool against Isoproterenol-Induced Myocardial Infarction. (2021) Life (Basel). 11, Pubmed Life (Basel)
Borate Ameliorates Sodium Nitrite-Induced Oxidative Stress Through Regulation of Oxidant/Antioxidant Status: Involvement of the Nrf2/HO-1 and NF-κB Pathways. (2021) Biol Trace Elem Res. Pubmed Biol Trace Elem Res
NIX protein enhances antioxidant capacity of and reduces the apoptosis induced by HSP90 inhibitor luminespib/NVP-AUY922 in PC12 cells. (2021) Cell Stress Chaperones. Pubmed Cell Stress Chaperones
Mitochondria autophagy: a potential target for cancer therapy. (2021) J Drug Target. 1-16 Pubmed J Drug Target
The anti-melanogenic effects of ellagic acid through induction of autophagy in melanocytes and suppression of UVA-activated α-MSH pathways via Nrf2 activation in keratinocytes. (2021) Biochem Pharmacol. 185, 114454 Pubmed Biochem Pharmacol
Roles of CNC Transcription Factors NRF1 and NRF2 in Cancer. (2021) Cancers (Basel). 13, Pubmed Cancers (Basel) PMC Article
Differences in cell death in methionine versus cysteine depletion. (2021) Environ Mol Mutagen. Pubmed Environ Mol Mutagen
A review of the biological activity and pharmacology of cryptotanshinone, an important active constituent in Danshen. (2021) Biomed Pharmacother. 137, 111332 Pubmed Biomed Pharmacother
The polysaccharides from the fruiting body prevent lipopolysaccharide/D-galactosamine-induced acute liver injury the miR-122-Nrf2/ARE pathways. (2021) Food Funct. Pubmed Food Funct
A Marine Carotenoid of Fucoxanthinol Accelerates the Growth of Human Pancreatic Cancer PANC-1 Cells. (2021) Nutr Cancer. 1-16 Pubmed Nutr Cancer
Patient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggressive Murine Hepatoblastomas. (2021) Cell Mol Gastroenterol Hepatol. Pubmed Cell Mol Gastroenterol Hepatol
Potential of Sulforaphane as a Natural Immune System Enhancer: A Review. (2021) Molecules. 26, Pubmed Molecules PMC Article
Ethyl ferulate, a lipophilic phenylpropanoid, prevents diabetes-associated renal injury in rats by amelioration of hyperglycemia-induced oxidative stress via activation of nuclear factor erythroid 2-related factor 2. (2021) J Food Biochem. e13607 Pubmed J Food Biochem
Maltol inhibits the progression of osteoarthritis the nuclear factor-erythroid 2-related factor-2/heme oxygenase-1 signal pathway and . (2021) Food Funct. 12, 1327-1337 Pubmed Food Funct
Nephroprotective effect of umbelliferone against cisplatin-induced kidney damage is mediated by regulation of NRF2, cytoglobin, SIRT1/FOXO-3, and NF- kB-p65 signaling pathways. (2021) J Biochem Mol Toxicol. e22738 Pubmed J Biochem Mol Toxicol
Dietary taurine modulates hepatic oxidative status, ER stress and inflammation in juvenile turbot (Scophthalmus maximus L.) fed high carbohydrate diets. (2021) Fish Shellfish Immunol. 109, 1-11 Pubmed Fish Shellfish Immunol
A novel role of the mitochondrial iron-sulfur cluster assembly protein ISCU-1/ISCU in longevity and stress response. (2021) Geroscience. Pubmed Geroscience
Nrf2 and β-catenin coactivation in hepatocellular cancer: Biological and therapeutic implications. (2021) Hepatology. Pubmed Hepatology
The protective role of luteolin against the methotrexate-induced hepato-renal toxicity via its antioxidative, anti-inflammatory, and anti-apoptotic effects in rats. (2021) Hum Exp Toxicol. 960327121991905 Pubmed Hum Exp Toxicol
Toxicity assessment of Lemna solid waste dumpsite (Calabar, Nigeria) using different extraction methods and toxicological responses of PLHC-1 cells. (2021) Environ Toxicol Pharmacol. 82, 103554 Pubmed Environ Toxicol Pharmacol
Pinoresinol diglucoside attenuates neuroinflammation, apoptosis and oxidative stress in a mice model with Alzheimer's disease. (2021) Neuroreport. 32, 259-267 Pubmed Neuroreport
Physical plasma-derived oxidants sensitize pancreatic cancer cells to ferroptotic cell death. (2021) Free Radic Biol Med. Pubmed Free Radic Biol Med
Inhibition of the NRF2/KEAP1 Axis: A Promising Therapeutic Strategy to Alter Redox Balance of Cancer Cells. (2021) Antioxid Redox Signal. Pubmed Antioxid Redox Signal
Dihydromyricetin reverses MRP2-induced multidrug resistance by preventing NF-κB-Nrf2 signaling in colorectal cancer cell. (2021) Phytomedicine. 82, 153414 Pubmed Phytomedicine
ROS‑mediated hypomethylation of PRDX5 promotes STAT3 binding and activates the Nrf2 signaling pathway in NSCLC. (2021) Int J Mol Med. 47, 573-582 Pubmed Int J Mol Med PMC Article
Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress. (2021) Free Radic Biol Med. 164, 1-12 Pubmed Free Radic Biol Med
1-Bromopropane-induced apoptosis in OVCAR-3 cells via oxidative stress and inactivation of Nrf2. (2021) Toxicol Ind Health. 37, 59-67 Pubmed Toxicol Ind Health
Polygalacin D suppresses esophageal squamous cell carcinoma growth and metastasis through regulating miR-142-5p/Nrf2 axis. (2021) Free Radic Biol Med. 164, 58-75 Pubmed Free Radic Biol Med
Nrf2-induced miR-23a-27a-24-2 cluster modulates damage repair of intestinal mucosa by targeting the Bach1/HO-1 axis in inflammatory bowel diseases. (2021) Free Radic Biol Med. 163, 1-9 Pubmed Free Radic Biol Med
n-BuOH extract of Bletilla striata exerts chemopreventive effects on lung against SiO nanoparticles through activation of Nrf2 pathway. (2021) Phytomedicine. 82, 153445 Pubmed Phytomedicine
Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice. (2021) Mol Med Rep. 23, 1 Pubmed Mol Med Rep PMC Article
(+)-Usnic acid modulates the Nrf2-ARE pathway in FaDu hypopharyngeal carcinoma cells. (2021) Mol Cell Biochem. Pubmed Mol Cell Biochem
Corrigendum to "Abrus agglutinin inhibits oral carcinogenesis through inactivation of NRF2 signaling pathway" [Int J Biol Macromol. 2020; 155:1123-1132.]. (2021) Int J Biol Macromol. 169, 599-600 Pubmed Int J Biol Macromol
Role of pyroptosis in spinal cord injury and its therapeutic implications. (2021) J Adv Res. 28, 97-109 Pubmed J Adv Res PMC Article
Glutamine pretreatment protects bovine mammary epithelial cells from inflammation and oxidative stress induced by γ-d-glutamyl-meso-diaminopimelic acid (iE-DAP). (2021) J Dairy Sci. 104, 2123-2139 Pubmed J Dairy Sci
Protection of 6-OHDA neurotoxicity by PGF through FP-ERK-Nrf2 signaling in SH-SY5Y cells. (2021) Toxicology. 450, 152686 Pubmed Toxicology
Myricetin: A review of the most recent research. (2021) Biomed Pharmacother. 134, 111017 Pubmed Biomed Pharmacother
A comprehensive understanding about the pharmacological effect of diallyl disulfide other than its anti-carcinogenic activities. (2021) Eur J Pharmacol. 893, 173803 Pubmed Eur J Pharmacol
ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer. (2021) Genes Dev. 35, 218-233 Pubmed Genes Dev PMC Article
MicroRNA-mediated autophagy regulation in cancer therapy: The role in chemoresistance/chemosensitivity. (2021) Eur J Pharmacol. 892, 173660 Pubmed Eur J Pharmacol
Efficient iron utilization compensates for loss of extracellular matrix of ovarian cancer spheroids. (2021) Free Radic Biol Med. 164, 369-380 Pubmed Free Radic Biol Med
miR‑126 overexpression attenuates oxygen‑glucose deprivation/reperfusion injury by inhibiting oxidative stress and inflammatory response via the activation of SIRT1/Nrf2 signaling pathway in human umbilical vein endothelial cells. (2021) Mol Med Rep. 23, 1 Pubmed Mol Med Rep PMC Article
Publisher Correction: Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers. (2021) Nat Commun. 12, 506 Pubmed Nat Commun PMC Article
Low Dose of Trichostatin A Improves Radiation Resistance by Activating Akt/Nrf2-Dependent Antioxidation Pathway in Cancer Cells. (2021) Radiat Res. Pubmed Radiat Res
Different Modulatory Effects of Four Methicillin-Resistant Clones on MG-63 Osteoblast-Like Cells. (2021) Biomolecules. 11, Pubmed Biomolecules PMC Article
Exacerbation of Coagulation and Cardiac Injury in Rats with Cisplatin-Induced Nephrotoxicity Following Intratracheal Instillation of Cerium Oxide Nanoparticles. (2021) Cell Physiol Biochem. 55, 1-16 Pubmed Cell Physiol Biochem
Cyclophilin D-dependent mitochondrial permeability transition amplifies inflammatory reprogramming in endotoxemia. (2021) FEBS Open Bio. Pubmed FEBS Open Bio
Anti-tumor activity of resveratrol against gastric cancer: a review of recent advances with an emphasis on molecular pathways. (2021) Cancer Cell Int. 21, 66 Pubmed Cancer Cell Int PMC Article
Curcumin: An Insight to Molecular Pathways Involved in Anticancer Activity. (2021) Mini Rev Med Chem. Pubmed Mini Rev Med Chem
The Ubiquitin E3 Ligase TRIM21 Promotes Hepatocarcinogenesis by Suppressing the p62-Keap1-Nrf2 Antioxidant Pathway. (2021) Cell Mol Gastroenterol Hepatol. Pubmed Cell Mol Gastroenterol Hepatol
Importance of Heme Oxygenase-1 in Gastrointestinal Cancers: Functions, Inductions, Regulations, and Signaling. (2021) J Gastrointest Cancer. Pubmed J Gastrointest Cancer
Overcoming hypoxia-induced resistance of pancreatic and lung tumor cells by disrupting the PERK-NRF2-HIF-axis. (2021) Cell Death Dis. 12, 82 Pubmed Cell Death Dis PMC Article
Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects. (2021) Pharmacol Res. 105444 Pubmed Pharmacol Res
Exome of Radiation-induced Rat Mammary Carcinoma Shows Copy-number Losses and Mutations in Human-relevant Cancer Genes. (2021) Anticancer Res. 41, 55-70 Pubmed Anticancer Res
Fumonisin B alters global m6A RNA methylation and epigenetically regulates Keap1-Nrf2 signaling in human hepatoma (HepG2) cells. (2021) Arch Toxicol. Pubmed Arch Toxicol
Nrf2 regulates cell motility through RhoA-ROCK1 signalling in non-small-cell lung cancer cells. (2021) Sci Rep. 11, 1247 Pubmed Sci Rep PMC Article
Oxindole-curcumin hybrid compound enhances the transcription of γ-glutamylcysteine ligase. (2021) Eur J Pharmacol. 896, 173898 Pubmed Eur J Pharmacol
Harnessing the Co-vulnerabilities of Amino Acid-Restricted Cancers. (2021) Cell Metab. 33, 9-20 Pubmed Cell Metab PMC Article
Identification of a subset of immunosuppressive P2RX1-negative neutrophils in pancreatic cancer liver metastasis. (2021) Nat Commun. 12, 174 Pubmed Nat Commun PMC Article
Activation of Nrf2 by Electrophiles Is Largely Independent of the Selenium Status of HepG2 Cells. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel)
Keap1-Nrf2 Pathway Regulates ALDH and Contributes to Radioresistance in Breast Cancer Stem Cells. (2021) Cells. 10, Pubmed Cells PMC Article
Anti-inflammatory activity of the water extract of Chloranthus serratus roots in LPS-stimulated RAW264.7 cells mediated by the Nrf2/HO-1, MAPK and NF-κB signaling pathways. (2021) J Ethnopharmacol. 271, 113880 Pubmed J Ethnopharmacol
Modulatory effect of Tagetes erecta flowers essential oils via Nrf2/HO-1/NF-κB/p65 axis mediated suppression of N-methyl-N'nitro-N-nitroguanidine (MNNG) induced gastric cancer in rats. (2021) Mol Cell Biochem. Pubmed Mol Cell Biochem
Current Perspectives on the Role of Nrf2 in 5-Fluorouracil Resistance in Colorectal Cancer. (2021) Anticancer Agents Med Chem. Pubmed Anticancer Agents Med Chem
Nrf2 overexpression increases risk of high tumor mutation burden in acute myeloid leukemia by inhibiting MSH2. (2021) Cell Death Dis. 12, 20 Pubmed Cell Death Dis PMC Article
MOAP-1-mediated dissociation of p62/SQSTM1 bodies releases Keap1 and suppresses Nrf2 signaling. (2021) EMBO Rep. 22, e50854 Pubmed EMBO Rep PMC Article
Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling. (2021) Food Funct. 12, 696-705 Pubmed Food Funct
Germacrone alleviates neurological deficits following traumatic brain injury by modulating neuroinflammation and oxidative stress. (2021) BMC Complement Med Ther. 21, 6 Pubmed BMC Complement Med Ther PMC Article
Loss of Tid1/DNAJA3 Co-Chaperone Promotes Progression and Recurrence of Hepatocellular Carcinoma after Surgical Resection: A Novel Model to Stratify Risk of Recurrence. (2021) Cancers (Basel). 13, Pubmed Cancers (Basel) PMC Article
Dietary intake of walnut prevented -associated gastric cancer through rejuvenation of chronic atrophic gastritis. (2021) J Clin Biochem Nutr. 68, 37-50 Pubmed J Clin Biochem Nutr PMC Article
Pelargonidin ameliorates MCAO-induced cerebral ischemia/reperfusion injury in rats by the action on the Nrf2/HO-1 pathway. (2021) Transl Neurosci. 12, 20-31 Pubmed Transl Neurosci PMC Article
7β-(3-Ethyl--crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro- Notonipetranone Attenuates Neuropathic Pain by Suppressing Oxidative Stress, Inflammatory and Pro-Apoptotic Protein Expressions. (2021) Molecules. 26, Pubmed Molecules PMC Article
Xanthohumol suppresses inflammation in chondrocytes and ameliorates osteoarthritis in mice. (2021) Biomed Pharmacother. 137, 111238 Pubmed Biomed Pharmacother
Synthesis of glutathione as a central aspect of PAH toxicity in liver cells: A comparison between phenanthrene, Benzo[b]Fluoranthene and their mixtures. (2021) Ecotoxicol Environ Saf. 208, 111637 Pubmed Ecotoxicol Environ Saf
L. Bulb Extracts Modulate Oxidative Stress and Redox Signaling in HepG2 Cells. (2021) Molecules. 26, Pubmed Molecules PMC Article
Mangiferin prevents the impairment of mitochondrial dynamics and an increase in oxidative stress caused by excessive fluoride in SH-SY5Y cells. (2021) J Biochem Mol Toxicol. e22705 Pubmed J Biochem Mol Toxicol
The Taming of Nuclear Factor Erythroid-2-Related Factor-2 (Nrf2) Deglycation by Fructosamine-3-Kinase (FN3K)-Inhibitors-A Novel Strategy to Combat Cancers. (2021) Cancers (Basel). 13, Pubmed Cancers (Basel) PMC Article
The Isothiocyanate Sulforaphane Depends on the Nrf2/γ-GCL/GSH Axis to Prevent Mitochondrial Dysfunction in Cells Exposed to Methylglyoxal. (2021) Neurochem Res. Pubmed Neurochem Res
Implications of hydrogen sulfide in liver pathophysiology: Mechanistic insights and therapeutic potential. (2021) J Adv Res. 27, 127-135 Pubmed J Adv Res PMC Article
Tavarua Deoxyriboside A and Jasplakinolide as Potential Neuroprotective Agents: Effects on Cellular Models of Oxidative Stress and Neuroinflammation. (2021) ACS Chem Neurosci. 12, 150-162 Pubmed ACS Chem Neurosci
Concentration-Dependent Pro- and Antitumor Activities of Quercetin in Human Melanoma Spheroids: Comparative Analysis of 2D and 3D Cell Culture Models. (2021) Molecules. 26, Pubmed Molecules PMC Article
Inhibitory effects of nodakenin on inflammation and cell death in lipopolysaccharide-induced liver injury mice. (2021) Phytomedicine. 81, 153411 Pubmed Phytomedicine
β-hydroxybutyrate does not alter the effects of glucose deprivation on breast cancer cells. (2021) Oncol Lett. 21, 65 Pubmed Oncol Lett PMC Article
Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis. (2021) Cell Metab. 33, 174-189.e7 Pubmed Cell Metab PMC Article
The Effect of Novel Oleanolic Acid Oximes Conjugated with Indomethacin on the Nrf2-ARE And NF-κB Signaling Pathways in Normal Hepatocytes and Human Hepatocellular Cancer Cells. (2020) Pharmaceuticals (Basel). 14, Pubmed Pharmaceuticals (Basel) PMC Article
Metformin reverses chemoresistance in non-small cell lung cancer via accelerating ubiquitination-mediated degradation of Nrf2. (2020) Transl Lung Cancer Res. 9, 2337-2355 Pubmed Transl Lung Cancer Res PMC Article
Particulate Matter-Induced Inflammation/Oxidative Stress in Macrophages: Fucosterol from as a Potent Protector, Activated via NF-κB/MAPK Pathways and Nrf2/HO-1 Involvement. (2020) Mar Drugs. 18, Pubmed Mar Drugs PMC Article
Crocin reverses 1-methyl-3-nitroso-1-nitroguanidine (MNNG)-induced malignant transformation in GES-1 cells through the Nrf2/Hippo signaling pathway. (2020) J Gastrointest Oncol. 11, 1242-1252 Pubmed J Gastrointest Oncol PMC Article
Metabolomic and Transcriptomic Analysis of MCF-7 Cells Exposed to 23 Chemicals at Human-Relevant Levels: Estimation of Individual Chemical Contribution to Effects. (2020) Environ Health Perspect. 128, 127008 Pubmed Environ Health Perspect PMC Article
Ziziphus spina-christi leaf extract mitigates mercuric chloride-induced cortical damage in rats. (2020) Comb Chem High Throughput Screen. Pubmed Comb Chem High Throughput Screen
Nrf2-A Molecular Target for Sepsis Patients in Critical Care. (2020) Biomolecules. 10, Pubmed Biomolecules PMC Article
/LKB1 Mutations in NSCLC Are Associated with KEAP1/NRF2-Dependent Radiotherapy Resistance Targetable by Glutaminase Inhibition. (2020) Clin Cancer Res. Pubmed Clin Cancer Res
Enhancer-bound Nrf2 licenses HIF-1α transcription under hypoxia to promote cisplatin resistance in hepatocellular carcinoma cells. (2020) Aging (Albany NY). 13, 364-375 Pubmed Aging (Albany NY) PMC Article
Hydrogen Sulfide and Carnosine: Modulation of Oxidative Stress and Inflammation in Kidney and Brain Axis. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel) PMC Article
Fruit Has Anti-Inflammatory Effect and Induces Osteogenic Differentiation by Regulating Nrf2/HO-1 Signaling Pathway in In Vitro and In Vivo Models of Periodontitis. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel) PMC Article
NRF2 Regulation by Noncoding RNAs in Cancers: The Present Knowledge and the Way Forward. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel) PMC Article
High Expression of NRF2 Is Associated with Increased Tumor-Infiltrating Lymphocytes and Cancer Immunity in ER-Positive/HER2-Negative Breast Cancer. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel) PMC Article
Andrographolide, an Anti-Inflammatory Multitarget Drug: All Roads Lead to Cellular Metabolism. (2020) Molecules. 26, Pubmed Molecules PMC Article
The KEAP1-NRF2 System as a Molecular Target of Cancer Treatment. (2020) Cancers (Basel). 13, Pubmed Cancers (Basel) PMC Article
Identifying Clear Cell Renal Cell Carcinoma Coexpression Networks Associated with Opioid Signaling and Survival. (2020) Cancer Res. Pubmed Cancer Res
Anti-Viral Potential and Modulation of Nrf2 by Curcumin: Pharmacological Implications. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel) PMC Article
Dietary Ferulic Acid Supplementation Improves Antioxidant Capacity and Lipid Metabolism in Weaned Piglets. (2020) Nutrients. 12, Pubmed Nutrients PMC Article
Dissecting molecular mechanisms underlying HO-induced apoptosis of mouse bone marrow mesenchymal stem cell: role of Mst1 inhibition. (2020) Stem Cell Res Ther. 11, 526 Pubmed Stem Cell Res Ther PMC Article
Biochemical study on the protective effect of curcumin on acetaminophen and gamma-irradiation induced hepatic toxicity in rats. (2020) Environ Toxicol. Pubmed Environ Toxicol
PP04 Ameliorates High-Fat Diet-Induced Hyperlipidemia by Regulating Lipid Metabolism in C57BL/6N Mice. (2020) J Agric Food Chem. 68, 15154-15163 Pubmed J Agric Food Chem
[6]-Gingerol impedes 7,12-dimethylbenz(a)anthracene-induced inflammation and cell proliferation-associated hamster buccal pouch carcinogenesis through modulating Nrf2 signaling events. (2020) J Biochem Mol Toxicol. e22689 Pubmed J Biochem Mol Toxicol
Vicenin-2 inhibits the Helicobacterium pylori infection associated gastric carcinogenic events through modulation of PI3K/AKT and Nrf2 signaling in GES-1 cells. (2020) J Biochem Mol Toxicol. e22680 Pubmed J Biochem Mol Toxicol
Inhibitory Effect of Black Radish ( L. var. ) Extracts on Lipopolysaccharide-Induced Inflammatory Response in the Mouse Monocyte/Macrophage-Like Cell Line RAW 264.7. (2020) Prev Nutr Food Sci. 25, 408-421 Pubmed Prev Nutr Food Sci PMC Article
Hybrid E/M Phenotype(s) and Stemness: A Mechanistic Connection Embedded in Network Topology. (2020) J Clin Med. 10, Pubmed J Clin Med PMC Article
NRF2 and the Ambiguous Consequences of Its Activation during Initiation and the Subsequent Stages of Tumourigenesis. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel) PMC Article
Emerging mechanisms and applications of ferroptosis in the treatment of resistant cancers. (2020) Biomed Pharmacother. 130, 110710 Pubmed Biomed Pharmacother
[Regulatory effect of Jinkui Shenqi Pills on the gene expression of the Nrf2 signaling pathway in cyclophosphamide-induced testis injury in mice]. (2020) Zhonghua Nan Ke Xue. 26, 160-166 Pubmed Zhonghua Nan Ke Xue
NETO2 promotes esophageal cancer progression by inducing proliferation and metastasis via PI3K/AKT and ERK pathway. (2021) Int J Biol Sci. 17, 259-270 Pubmed Int J Biol Sci PMC Article
Berbamine Suppresses the Progression of Bladder Cancer by Modulating the ROS/NF-B Axis. (2021) Oxid Med Cell Longev. 2021, 8851763 Pubmed Oxid Med Cell Longev PMC Article
Daphnetin Attenuated Cisplatin-Induced Acute Nephrotoxicity With Enhancing Antitumor Activity of Cisplatin by Upregulating SIRT1/SIRT6-Nrf2 Pathway. (2020) Front Pharmacol. 11, 579178 Pubmed Front Pharmacol PMC Article
Piceatannol Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by Modulation of Nrf2/HO-1/NFκB Axis. (2020) Front Pharmacol. 11, 614897 Pubmed Front Pharmacol PMC Article
The Nrf2/PGC1 Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer. (2020) Oxid Med Cell Longev. 2020, 4830418 Pubmed Oxid Med Cell Longev PMC Article
The anti-arthritis effect of sulforaphane, an activator of Nrf2, is associated with inhibition of both B cell differentiation and the production of inflammatory cytokines. (2021) PLoS One. 16, e0245986 Pubmed PLoS One PMC Article
Cardiac Inflammation, Oxidative Stress, Nrf2 Expression, and Coagulation Events in Mice with Experimental Chronic Kidney Disease. (2021) Oxid Med Cell Longev. 2021, 8845607 Pubmed Oxid Med Cell Longev PMC Article
Long-term transcriptomic and proteomic effects in Sprague Dawley rat thyroid and plasma after internal low dose 131I exposure. (2020) PLoS One. 15, e0244098 Pubmed PLoS One PMC Article
Ubiquitin-Like Modifier Activating Enzyme 1 as a Novel Diagnostic and Prognostic Indicator That Correlates With Ferroptosis and the Malignant Phenotypes of Liver Cancer Cells. (2020) Front Oncol. 10, 592413 Pubmed Front Oncol PMC Article
Nrf2 Mediates Metabolic Reprogramming in Non-Small Cell Lung Cancer. (2020) Front Oncol. 10, 578315 Pubmed Front Oncol PMC Article
Pharmacological Effects of Salvianolic Acid B Against Oxidative Damage. (2020) Front Pharmacol. 11, 572373 Pubmed Front Pharmacol PMC Article
Glucocorticoid transiently upregulates mitochondrial biogenesis in the osteoblast. Chin J Physiol. 63, 286-293 Pubmed Chin J Physiol
Magnesium Isoglycyrrhizinate Alleviates Arsenic Trioxide-Induced Cardiotoxicity: Contribution of Nrf2 and TLR4/NF-κB Signaling Pathway. (2021) Drug Des Devel Ther. 15, 543-556 Pubmed Drug Des Devel Ther PMC Article
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