Which NRF2 Products Have Peer Reviewed Studies

English: Graph of Nrf2 publications (pubmed search) by year (Photo credit: Wikipedia)

There are currently over 2300 articles (peer reviewed clinical reviews and studies) on Pubmed.gov on the topic of NRF2 Activation. There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to Pubmed.gov and type in the name of their product. Pubmed is a website operated by the National Institute of Health (NIH). PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources. Last 200 NRF-2 Studies published on Pubmed

Qin X, Xu X, Hou X, Liang R, Chen L, Hao Y, Gao A, Du X, Zhao L, Shi Y and Li Q. The pharmacological properties and corresponding mechanisms of farrerol: a comprehensive review. (2022) Pharm Biol. 60, 9-16 Pubmed Pharm Biol

Zhao YJ, Qiao H, Liu DF, Li J, Li JX, Chang SE, Lu T, Li FT, Wang D, Li HP, He XJ and Wang F. Lithium promotes recovery after spinal cord injury. (2022) Neural Regen Res. 17, 1324-1333 Pubmed Neural Regen Res

Chen Y, Wang Y, Charkoftaki G, Orlicky DJ, Davidson E, Wan F, Ginsberg G, Thompson DC and Vasiliou V. Oxidative stress and genotoxicity in 1,4-dioxane liver toxicity as evidenced in a mouse model of glutathione deficiency. (2022) Sci Total Environ. 806, 150703 Pubmed Sci Total Environ

Li L, Zhang H, Chen B, Xia B, Zhu R, Liu Y, Dai X, Ye Z, Zhao D, Mo F, Gao S, Orekhov AN, Prentki M, Wang L, Guo S and Zhang D. BaZiBuShen alleviates cognitive deficits and regulates Sirt6/NRF2/HO-1 and Sirt6/P53-PGC-1α-TERT signaling pathways in aging mice. (2022) J Ethnopharmacol. 282, 114653 Pubmed J Ethnopharmacol

Liang R, Tong X, Dong Z, Qin W, Fan L, Bai Z, Zhang Z, Xiang T, Wang Z and Tan N. Suhuang antitussive capsule ameliorates post-infectious cough in mice through AhR-Nrf2 pathway. (2022) J Ethnopharmacol. 283, 114664 Pubmed J Ethnopharmacol

Xu LT, Wang T, Fang KL, Zhao Y, Wang XN, Ren DM and Shen T. The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB. (2022) J Ethnopharmacol. 283, 114694 Pubmed J Ethnopharmacol

Wang B, Zhang QH, Li XJ, Wang SQ, Chen XB, Yu B and Liu HM. Discovery of a cinnamyl piperidine derivative as new neddylation inhibitor for gastric cancer treatment. (2021) Eur J Med Chem. 226, 113896 Pubmed Eur J Med Chem

Sallam AM, Darwish SF, El-Dakroury WA and Radwan E. Olmesartan niosomes ameliorates the Indomethacin-induced gastric ulcer in rats: Insights on MAPK and Nrf2/HO-1 signaling pathway. (2021) Pharm Res. Pubmed Pharm Res

Chang LC, Fan CW, Tseng WK and Hua CC. The level of S-glutathionylated protein is a predictor for metastasis in colorectal cancer and correlated with those of Nrf2/Keap1 pathway. (2021) Biomarkers. 26, 780-787 Pubmed Biomarkers

Song Z, Gao C, Jiang Q, Xu J, Xiong L, Liu K, Sun D, Li H and Chen L. Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity. (2021) Phytochemistry. 192, 112971 Pubmed Phytochemistry

Li Y, Qiu X, Lu Z, Zhan F, Yang M, Sarath Babu V, Li J, Qin Z and Lin L. Molecular and functional characterization of MST2 in grass carp during bacterial infection. (2021) Fish Shellfish Immunol. 119, 19-30 Pubmed Fish Shellfish Immunol

Khayal EE, Ibrahim HM, Shalaby AM, Alabiad MA and El-Sheikh AA. Combined lead and zinc oxide-nanoparticles induced thyroid toxicity through 8-OHdG oxidative stress-mediated inflammation, apoptosis, and Nrf2 activation in rats. (2021) Environ Toxicol. 36, 2589-2604 Pubmed Environ Toxicol

Hamidi-Zad Z, Moslehi A and Rastegarpanah M. Attenuating effects of allantoin on oxidative stress in a mouse model of nonalcoholic steatohepatitis: role of SIRT1/Nrf2 pathway. (2021) Res Pharm Sci. 16, 651-659 Pubmed Res Pharm Sci PMC Article

Zou Y, Li S, Li X, Sun Y, Ma M, Tian H, Wang N, Yuan J and Xiao C. Isosinensetin alleviates the injury of human bronchial epithelial cells induced by PM. (2021) Exp Ther Med. 22, 1435 Pubmed Exp Ther Med PMC Article

Dai C, Yusuf A, Sun H, Shu G and Deng X. A characterized saponin extract of Panax japonicus suppresses hepatocyte EMT and HSC activation in vitro and CCl-provoked liver fibrosis in mice: Roles of its modulatory effects on the Akt/GSK3β/Nrf2 cascade. (2021) Phytomedicine. 93, 153746 Pubmed Phytomedicine

Yang D, Li J, Liang C, Tian L, Shi C, Hui N, Liu Y, Ling M, Xin L, Wan M, Li H, Zhao Q, Ren X, Liu H and Cao W. Syringa microphylla Diels: A comprehensive review of its phytochemical, pharmacological, pharmacokinetic, and toxicological characteristics and an investigation into its potential health benefits. (2021) Phytomedicine. 93, 153770 Pubmed Phytomedicine

Liu W, Tang P, Wang J, Ye W, Ge X, Rong Y, Ji C, Wang Z, Bai J, Fan J, Yin G and Cai W. Extracellular vesicles derived from melatonin-preconditioned mesenchymal stem cells containing USP29 repair traumatic spinal cord injury by stabilizing NRF2. (2021) J Pineal Res. 71, e12769 Pubmed J Pineal Res

Zhu L, Zhao Y, Yu L, He X, Wang Y, Jiang P, Yu R, Li W, Dong B, Wang X and Dong Y. Overexpression of ADAM9 decreases radiosensitivity of hepatocellular carcinoma cell by activating autophagy. (2021) Bioengineered. 12, 5516-5528 Pubmed Bioengineered

Pepe G, Sfogliarini C, Rizzello L, Battaglia G, Pinna C, Rovati G, Ciana P, Brunialti E, Mornata F, Maggi A, Locati M and Vegeto E. ERα-independent NRF2-mediated immunoregulatory activity of tamoxifen. (2021) Biomed Pharmacother. 144, 112274 Pubmed Biomed Pharmacother

Delgobo M, Gonçalves RM, Delazeri MA, Falchetti M, Zandoná A, Nascimento das Neves R, Almeida K, Fagundes AC, Gelain DP, Fracasso JI, Macêdo GB, Priori L, Bassani N, Bishop AJR, Forcelini CM, Moreira JCF and Zanotto-Filho A. Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer. (2021) Free Radic Biol Med. 177, 58-71 Pubmed Free Radic Biol Med

Deng J, Huang M and Wu H. Protective effect of limonin against doxorubicin-induced cardiotoxicity via activating nuclear factor - like 2 and Sirtuin 2 signaling pathways. (2021) Bioengineered. 12, 7975-7984 Pubmed Bioengineered

Wang X, Yang B, Li Y, Luo J and Wang Y. AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway. (2021) Mol Med Rep. 24, Pubmed Mol Med Rep PMC Article

Li M, Kong Y, Wu X, Yin Z, Niu X and Wang G. Dietary α-lipoic acid can alleviate the bioaccumulation, oxidative stress, cell apoptosis, and inflammation induced by lead (Pb) in Channa argus. (2021) Fish Shellfish Immunol. 119, 249-261 Pubmed Fish Shellfish Immunol

Lv JJ, Yuan KK, Lu MY, He ZB, Li HY and Yang WD. Responses of JNK signaling pathway to the toxic dinoflagellate Prorocentrum lima in the mussel Perna viridis. (2021) Ecotoxicol Environ Saf. 227, 112905 Pubmed Ecotoxicol Environ Saf

Mazarakis N, Higgins RA, Anderson J, Toh ZQ, Luwor RB, Snibson KJ, Karagiannis TC, Do LAH and Licciardi PV. The effects of the dietary compound L-sulforaphane against respiratory pathogens. (2021) Int J Antimicrob Agents. 58, 106460 Pubmed Int J Antimicrob Agents

Malin D, Lee Y, Chepikova O, Strekalova E, Carlson A and Cryns VL. Methionine restriction exposes a targetable redox vulnerability of triple-negative breast cancer cells by inducing thioredoxin reductase. (2021) Breast Cancer Res Treat. 190, 373-387 Pubmed Breast Cancer Res Treat

Ye S, Li S, Ma Y, Hu D and Xiao F. Curcumin hinders PBDE-47-induced neutrophil extracellular traps release via Nrf2-associated ROS inhibition. (2021) Ecotoxicol Environ Saf. 225, 112779 Pubmed Ecotoxicol Environ Saf

Reis-Mendes A, Padrão AI, Duarte JA, Gonçalves-Monteiro S, Duarte-Araújo M, Remião F, Carvalho F, Sousa E, Bastos ML and Costa VM. Role of Inflammation and Redox Status on Doxorubicin-Induced Cardiotoxicity in Infant and Adult CD-1 Male Mice. (2021) Biomolecules. 11, Pubmed Biomolecules PMC Article

Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J and Zhong C. Correction to: Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer. (2021) J Exp Clin Cancer Res. 40, 349 Pubmed J Exp Clin Cancer Res PMC Article

Zhang P, Gao K, Zhang L, Sun H, Zhao X, Liu Y, Lv Z, Shi Q, Chen Y, Jiao D, Li Y, Gu W and Wang C. CRL2-KLHDC3 E3 ubiquitin ligase complex suppresses ferroptosis through promoting p14 degradation. (2021) Cell Death Differ. Pubmed Cell Death Differ

Mohamed GA, Ibrahim SRM, El-Agamy DS, Elsaed WM, Sirwi A, Asfour HZ, Koshak AE and Elhady SS. Terretonin as a New Protective Agent against Sepsis-Induced Acute Lung Injury: Impact on SIRT1/Nrf2/NF-κBp65/NLRP3 Signaling. (2021) Biology (Basel). 10, Pubmed Biology (Basel) PMC Article

Han Y, Wang C, Li X and Liang G. Oleanolic acid reduces oxidative stress and neuronal apoptosis after experimental subarachnoid hemorrhage by regulating Nrf2/HO-1 pathway. (2021) Drug Dev Res. Pubmed Drug Dev Res

Zhang H, Zhou L, Zhou Y, Wang L, Jiang W, Liu L, Yue S, Zheng P and Liu H. Intermittent hypoxia aggravates non-alcoholic fatty liver disease via RIPK3-dependent necroptosis-modulated Nrf2/NFκB signaling pathway. (2021) Life Sci. 285, 119963 Pubmed Life Sci

Lv J, Xie M, Zhao S, Qiu W, Wang S and Cao M. Nestin is essential for cellular redox homeostasis and gastric cancer metastasis through the mediation of the Keap1-Nrf2 axis. (2021) Cancer Cell Int. 21, 603 Pubmed Cancer Cell Int PMC Article

D'Amico R, Monaco F, Fusco R, Siracusa R, Impellizzeri D, Peritore AF, Crupi R, Gugliandolo E, Cuzzocrea S, Di Paola R, Genovese T and Cordaro M. Atrazine Inhalation Worsen Pulmonary Fibrosis Regulating the Nuclear Factor-Erythroid 2-Related Factor (Nrf2) Pathways Inducing Brain Comorbidities. (2021) Cell Physiol Biochem. 55, 704-725 Pubmed Cell Physiol Biochem

Fradejas-Villar N, Zhao W, Reuter U, Doengi M, Ingold I, Bohleber S, Conrad M and Schweizer U. Missense mutation in selenocysteine synthase causes cardio-respiratory failure and perinatal death in mice which can be compensated by selenium-independent GPX4. (2021) Redox Biol. 48, 102188 Pubmed Redox Biol PMC Article

Deng S, Wu D, Li L, Li J and Xu Y. TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2. (2021) Cell Mol Biol Lett. 26, 48 Pubmed Cell Mol Biol Lett PMC Article

Song IS, Jeong YJ, Jung Y, Park YH, Shim S, Kim SJ, Eom DW, Hong SM, Lee PCW, Kim SU and Jang SW. The sulfiredoxin-peroxiredoxin redox system regulates the stemness and survival of colon cancer stem cells. (2021) Redox Biol. 48, 102190 Pubmed Redox Biol PMC Article

Zhang H, Xiang D, Liu X and Xiang L. PPARα agonist relieves spinal cord injury in rats by activating Nrf2/HO-1 via the Raf-1/MEK/ERK pathway. (2021) Aging (Albany NY). 13, Pubmed Aging (Albany NY)

Shin MR, Lee JA, Kim M, Lee S, Oh M, Moon J, Nam JW, Choi H, Mun YJ and Roh SS. Gardeniae Fructus Attenuates Thioacetamide-Induced Liver Fibrosis in Mice via Both AMPK/SIRT1/NF-κB Pathway and Nrf2 Signaling. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Cai S, Fu S, Zhang W, Yuan X, Cheng Y and Fang J. SIRT6 silencing overcomes resistance to sorafenib by promoting ferroptosis in gastric cancer. (2021) Biochem Biophys Res Commun. 577, 158-164 Pubmed Biochem Biophys Res Commun

Ji R, Jia FY, Chen X, Wang ZH, Jin WY and Yang J. Salidroside alleviates oxidative stress and apoptosis via AMPK/Nrf2 pathway in DHT-induced human granulosa cell line KGN. (2021) Arch Biochem Biophys. 715, 109094 Pubmed Arch Biochem Biophys

Sun Y, Ma N, Yi J, Zhou L and Cai S. Gastroprotective effect and mechanisms of Chinese sumac fruits ( Mill.) on ethanol-induced gastric ulcers in mice. (2021) Food Funct. Pubmed Food Funct

Huang W, Chen K, Lu Y, Zhang D, Cheng Y, Li L, Huang W, He G, Liao H, Cai L, Tang Y, Zhao L and Pan M. ABCC5 facilitates the acquired resistance of sorafenib through the inhibition of SLC7A11-induced ferroptosis in hepatocellular carcinoma. (2021) Neoplasia. 23, 1227-1239 Pubmed Neoplasia PMC Article

Da C, Pu J, Liu Z, Wei J, Qu Y, Wu Y, Shi B, Yang J, He N and Hou P. HACE1-mediated NRF2 activation causes enhanced malignant phenotypes and decreased radiosensitivity of glioma cells. (2021) Signal Transduct Target Ther. 6, 399 Pubmed Signal Transduct Target Ther

Wan Y, Wang J, Xu JF, Tang F, Chen L, Tan YZ, Rao CL, Ao H and Peng C. and its ginsenosides: potential candidates for the prevention and treatment of chemotherapy-induced side effects. (2021) J Ginseng Res. 45, 617-630 Pubmed J Ginseng Res PMC Article

Zhang C, Li N, Liu YY, Yuan T, Yang S and Wang XP. Cox15 is a novel oncogene that required for lung cancer cell proliferation. (2021) Biochem Biophys Res Commun. 578, 70-76 Pubmed Biochem Biophys Res Commun

Gao F, Guo Z, Gao Y, Wang C, Wang H, Yao X and Shi B. Maternal oxidized soybean oil exposure in rats during lactation damages offspring kidneys via Nrf2/HO-1 and NF-κB signaling pathway. (2021) J Sci Food Agric. Pubmed J Sci Food Agric

Abulizi A, Ran J, Ye Y, An Y, Zhang Y, Huang Z, Lin S, Zhou H, Lin D, Wang L, Lin Z, Li M and Yang B. Ganoderic acid improves 5-fluorouracil-induced cognitive dysfunction in mice. (2021) Food Funct. Pubmed Food Funct

Vergoten G and Bailly C. Molecular docking study of britannin binding to PD-L1 and related anticancer pseudoguaianolide sesquiterpene lactones. (2021) J Recept Signal Transduct Res. 1-8 Pubmed J Recept Signal Transduct Res

Dang YY, Luo H, Li YM, Zhou Y, Luo X, Lin SM, Liu SP, Lee SM, Li CW and Dai XY. Curcumin prevents As-induced carcinogenesis through regulation of GSK3β/Nrf2. (2021) Chin Med. 16, 116 Pubmed Chin Med PMC Article

Yazaki K, Matsuno Y, Yoshida K, Sherpa M, Nakajima M, Matsuyama M, Kiwamoto T, Morishima Y, Ishii Y and Hizawa N. ROS-Nrf2 pathway mediates the development of TGF-β1-induced epithelial-mesenchymal transition through the activation of Notch signaling. (2021) Eur J Cell Biol. 100, 151181 Pubmed Eur J Cell Biol

Huang SS, Guo DY, Jia BB, Cai GL, Yan J, Lu Y and Yang ZX. Dimethyl itaconate alleviates the pyroptosis of macrophages through oxidative stress. (2021) BMC Immunol. 22, 72 Pubmed BMC Immunol PMC Article

Sabatier P, Beusch CM, Gencheva R, Cheng Q, Zubarev R and Arnér ESJ. Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin. (2021) Redox Biol. 48, 102184 Pubmed Redox Biol PMC Article

Čipak Gašparović A, Milković L, Rodrigues C, Mlinarić M and Soveral G. Peroxiporins Are Induced upon Oxidative Stress Insult and Are Associated with Oxidative Stress Resistance in Colon Cancer Cell Lines. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Cediel-Ulloa A, Isaxon C, Eriksson A, Primetzhofer D, Sortica MA, Haag L, Derr R, Hendriks G, Löndahl J, Gudmundsson A, Broberg K and Gliga AR. Toxicity of stainless and mild steel particles generated from gas-metal arc welding in primary human small airway epithelial cells. (2021) Sci Rep. 11, 21846 Pubmed Sci Rep PMC Article

Ding H, Chen Z, Wu K, Huang SM, Wu WL, LeBoeuf SE, Pillai RG, Rabinowitz JD and Papagiannakopoulos T. Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition. (2021) Sci Adv. 7, eabk1023 Pubmed Sci Adv PMC Article

Suwa T, Kobayashi M, Shirai Y, Nam JM, Tabuchi Y, Takeda N, Akamatsu S, Ogawa O, Mizowaki T, Hammond EM and Harada H. SPINK1 as a plasma marker for tumor hypoxia and a therapeutic target for radiosensitization. (2021) JCI Insight. 6, Pubmed JCI Insight

Shu G, Yusuf A, Dai C, Sun H and Deng X. Piperine inhibits AML-12 hepatocyte EMT and LX-2 HSC activation and alleviates mouse liver fibrosis provoked by CCl: roles in the activation of the Nrf2 cascade and subsequent suppression of the TGF-β1/Smad axis. (2021) Food Funct. 12, 11686-11703 Pubmed Food Funct

Hu Q, Lu X, Li G, Kang X, Chen K, Wang M, Liu S and Guan W. Mitoquinone treatment for the prevention of surgical adhesions via regulation of the NRF2/HO-1 signaling pathway in mice. (2021) Surgery. Pubmed Surgery

Ding Z, Xi J, Zhong M, Chen F, Zhao H, Zhang B and Fang J. Cynaropicrin Induces Cell Cycle Arrest and Apoptosis by Inhibiting PKM2 to Cause DNA Damage and Mitochondrial Fission in A549 Cells. (2021) J Agric Food Chem. 69, 13557-13567 Pubmed J Agric Food Chem

Shreevatsa B, Dharmashekara C, Swamy VH, Gowda MV, Achar RR, Kameshwar VH, Thimmulappa RK, Syed A, Elgorban AM, Al-Rejaie SS, Ortega-Castro J, Frau J, Flores-Holguín N, Shivamallu C, Kollur SP and Glossman-Mitnik D. Virtual Screening for Potential Phytobioactives as Therapeutic Leads to Inhibit NQO1 for Selective Anticancer Therapy. (2021) Molecules. 26, Pubmed Molecules PMC Article

Shin SW, Choi C, Kim H, Kim Y, Park S, Kim SY, Batinic-Haberle I and Park W. MnTnHex-2-PyP, Coupled to Radiation, Suppresses Metastasis of 4T1 and MDA-MB-231 Breast Cancer via AKT/Snail/EMT Pathways. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Camiña N and Penning TM. Genetic and epigenetic regulation of the NRF2-KEAP1 pathway in human lung cancer. (2021) Br J Cancer. Pubmed Br J Cancer

Sirwi A, Shaik RA, Alamoudi AJ, Eid BG, Kammoun AK, Ibrahim SRM, Mohamed GA, Abdallah HM and Abdel-Naim AB. Mokko Lactone Attenuates Doxorubicin-Induced Hepatotoxicity in Rats: Emphasis on Sirt-1/FOXO1/NF-κB Axis. (2021) Nutrients. 13, Pubmed Nutrients PMC Article

Kooshki L, Mahdavi P, Fakhri S, Akkol EK and Khan H. Targeting lactate metabolism and glycolytic pathways in the tumor microenvironment by natural products: A promising strategy in combating cancer. (2021) Biofactors. Pubmed Biofactors

Peng X, Zhang S, Jiao W, Zhong Z, Yang Y, Claret FX, Elkabets M, Wang F, Wang R, Zhong Y, Chen ZS and Kong D. Hydroxychloroquine synergizes with the PI3K inhibitor BKM120 to exhibit antitumor efficacy independent of autophagy. (2021) J Exp Clin Cancer Res. 40, 374 Pubmed J Exp Clin Cancer Res

Yang J, Mo J, Dai J, Ye C, Cen W, Zheng X, Jiang L and Ye L. Cetuximab promotes RSL3-induced ferroptosis by suppressing the Nrf2/HO-1 signalling pathway in KRAS mutant colorectal cancer. (2021) Cell Death Dis. 12, 1079 Pubmed Cell Death Dis PMC Article

Goto RL, Tablas MB, Prata GB, Espírito Santo SG, Fernandes AAH, Cogliati B, Barbisan LF and Romualdo GR. Vitamin D supplementation alleviates chemically-induced cirrhosis-associated hepatocarcinogenesis. (2021) J Steroid Biochem Mol Biol. 215, 106022 Pubmed J Steroid Biochem Mol Biol

Gowda P, Lathoria K, Umdor SB and Sen E. Brg1 mutation alters oxidative stress responses in glioblastoma. (2021) Neurochem Int. 150, 105189 Pubmed Neurochem Int

Wei J, Zhao Q, Zhang Y, Shi W, Wang H, Zheng Z, Meng L, Xin Y and Jiang X. Sulforaphane-Mediated Nrf2 Activation Prevents Radiation-Induced Skin Injury through Inhibiting the Oxidative-Stress-Activated DNA Damage and NLRP3 Inflammasome. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Li S, Wu R, Wang L, Dina Kuo HC, Sargsyan D, Zheng X, Wang Y, Su X and Kong AN. Triterpenoid ursolic acid drives metabolic rewiring and epigenetic reprogramming in treatment/prevention of human prostate cancer. (2021) Mol Carcinog. Pubmed Mol Carcinog

Yang L, Shen C, Estrada-Bernal A, Robb R, Chatterjee M, Sebastian N, Webb A, Mo X, Chen W, Krishnan S and Williams TM. Oncogenic KRAS drives radioresistance through upregulation of NRF2-53BP1-mediated non-homologous end-joining repair. (2021) Nucleic Acids Res. 49, 11067-11082 Pubmed Nucleic Acids Res PMC Article

Wen Y, Liu Y, Huang Q, Liu R, Liu J, Zhang F, Liu S and Jiang Y. Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway. (2021) Phytomedicine. 95, 153856 Pubmed Phytomedicine

Chen L, Wang J, Cai X, Chen S, Zhang J, Li B, Chen W, Guo X, Luo H and Chen J. Cyclometalated Ru(II)-isoquinoline complexes overcome cisplatin resistance of A549/DDP cells by downregulation of Nrf2 via Akt/GSK-3β/Fyn pathway. (2021) Bioorg Chem. 119, 105516 Pubmed Bioorg Chem

Abd El-Hameed NM, Abd El-Aleem SA, Khattab MA, Ali AH and Mohammed HH. Curcumin activation of nuclear factor E2-related factor 2 gene (Nrf2): Prophylactic and therapeutic effect in nonalcoholic steatohepatitis (NASH). (2021) Life Sci. 285, 119983 Pubmed Life Sci

Alyoussef A. Attenuation of experimentally induced atopic dermatitis in mice by sulforaphane: effect on inflammation and apoptosis. (2021) Toxicol Mech Methods. 1-9 Pubmed Toxicol Mech Methods

Sehati F, Ahmadi I, Farivar N, Ranjbaran M, Sadat-Shirazi MS, Nabavizadeh F, Mahla Shavakandi S and Ashabi G. Tannic acid protects aged brain against cerebral hypoperfusion via modulation of Nrf2 and inflammatory pathways. (2021) Neurosci Lett. 765, 136263 Pubmed Neurosci Lett

Hu W, Li Z, Wang W, Song M, Dong R, Zhou Y, Li Y and Wang D. Structural characterization of polysaccharide purified from and its pharmacological basis for application in Alzheimer's disease: endoplasmic reticulum stress. (2021) Food Funct. 12, 11009-11023 Pubmed Food Funct

Dhar R, Rana MN, Zhang L, Li Y, Li N, Hu Z, Yan C, Wang X, Zheng X, Liu H, Cui H, Li Z and Tang H. Phosphodiesterase 4B is required for NLRP3 inflammasome activation by positive feedback with Nrf2 in the early phase of LPS- induced acute lung injury. (2021) Free Radic Biol Med. 176, 378-391 Pubmed Free Radic Biol Med

Kim HY, Ahn SB, Hong JM, Oh JH, Saeed WK, Kim GS, Kim H, Kang JK, Kang S and Jun DW. BTT-105 ameliorates hepatic fibrosis in non-alcoholic fatty liver animal model. (2021) FASEB J. 35, e21979 Pubmed FASEB J

Mansour DF, Saleh DO, Ahmed-Farid OA, Rady M, Bakeer RM and Hashad IM. Ginkgo biloba extract (EGb 761) mitigates methotrexate-induced testicular insult in rats: Targeting oxidative stress, energy deficit and spermatogenesis. (2021) Biomed Pharmacother. 143, 112201 Pubmed Biomed Pharmacother

González-Bosch C, Boorman E, Zunszain PA and Mann GE. Short-chain fatty acids as modulators of redox signaling in health and disease. (2021) Redox Biol. 47, 102165 Pubmed Redox Biol PMC Article

Yuan J, Sun X, Che S, Zhang L, Ruan Z, Li X and Yang J. AhR-mediated CYP1A1 and ROS overexpression are involved in hepatotoxicity of decabromodiphenyl ether (BDE-209). (2021) Toxicol Lett. 352, 26-33 Pubmed Toxicol Lett

Kaur J, Gulati M, Gowthamarajan K, Vishwas S, Kumar Chellappan D, Gupta G, Dua K, Pandey NK, Kumar B and Singh SK. Combination therapy of vanillic acid and oxaliplatin co-loaded in polysaccharide based functionalized polymeric micelles could offer effective treatment for colon cancer: A hypothesis. (2021) Med Hypotheses. 156, 110679 Pubmed Med Hypotheses

Chen Q, Xu Z, Li X, Du D, Wu T, Zhou S, Yan W, Wu M, Jin Y, Zhang J and Wang S. Epigallocatechin gallate and theaflavins independently alleviate cyclophosphamide-induced ovarian damage by inhibiting the overactivation of primordial follicles and follicular atresia. (2021) Phytomedicine. 92, 153752 Pubmed Phytomedicine

Cassandri M, Pomella S, Rossetti A, Petragnano F, Milazzo L, Vulcano F, Camero S, Codenotti S, Cicchetti F, Maggio R, Festuccia C, Gravina GL, Fanzani A, Megiorni F, Catanoso M, Marchese C, Tombolini V, Locatelli F, Rota R and Marampon F. MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci PMC Article

Sun T, Yu S, Song X, Zhang J, Bao Q, Mei Q, Shen Q, Wang D and Ni G. Cold Plasma Irradiation Regulates Inflammation and Oxidative Stress in Human Bronchial Epithelial Cells and Human Non-Small Cell Lung Carcinoma. (2021) Radiat Res. Pubmed Radiat Res

Cruz-Gregorio A, Aranda-Rivera AK and Pedraza-Chaverri J. Nuclear factor erythroid 2-related factor 2 in human papillomavirus-related cancers. (2021) Rev Med Virol. e2308 Pubmed Rev Med Virol

Tian S, Jiang X, Tang Y and Han T. Laminaria japonica fucoidan ameliorates cyclophosphamide-induced liver and kidney injury possibly by regulating Nrf2/HO-1 and TLR4/NF-κB signaling pathways. (2021) J Sci Food Agric. Pubmed J Sci Food Agric

Lim JY, Yun DH, Lee JH, Kwon YB, Lee YM, Lee DH and Kim DK. Extract of Sprouts Suppresses Acetaminophen-Induced Hepatotoxicity in Mice by Inhibiting Oxidative Stress. (2021) Molecules. 26, Pubmed Molecules PMC Article

Wang S, Chao X, Jiang X, Wang T, Rodriguez Y, Yang L, Pacher P, Ni HM and Ding WX. Loss of acinar cell VMP1 triggers spontaneous pancreatitis in mice. (2021) Autophagy. 1-11 Pubmed Autophagy

Wu TJ, Hsieh YJ, Lu CW, Lee CJ and Hsu BG. Linagliptin Protects against Endotoxin-Induced Acute Kidney Injury in Rats by Decreasing Inflammatory Cytokines and Reactive Oxygen Species. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci PMC Article

Yamashita M. Auranofin: Past to Present, and repurposing. (2021) Int Immunopharmacol. 101, 108272 Pubmed Int Immunopharmacol

Bhattarai G, So HS, Kieu TTT, Kook SH, Lee JC and Jeon YM. Astaxanthin Inhibits Diabetes-Triggered Periodontal Destruction, Ameliorates Oxidative Complications in STZ-Injected Mice, and Recovers Nrf2-Dependent Antioxidant System. (2021) Nutrients. 13, Pubmed Nutrients PMC Article

Jiang Y, Southam AD, Trova S, Beke F, Alhazmi B, Francis T, Radotra A, di Maio A, Drayson MT, Bunce CM and Khanim FL. Valproic acid disables the Nrf2 anti-oxidant response in acute myeloid leukaemia cells enhancing reactive oxygen species-mediated killing. (2021) Br J Cancer. Pubmed Br J Cancer

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