Which NRF2 Products Have Peer Reviewed Studies

English: Graph of Nrf2 publications (pubmed search) by year (Photo credit: Wikipedia)

There are currently over 2300 articles (peer reviewed clinical reviews and studies) on Pubmed.gov on the topic of NRF2 Activation. There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to Pubmed.gov and type in the name of their product. Pubmed is a website operated by the National Institute of Health (NIH). PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources. Last 200 NRF-2 Studies published on Pubmed

Cheng L, Wang H, Li S, Liu Z and Wang C. New insights into the mechanism of Keap1-Nrf2 interaction based on cancer-associated mutations. (2021) Life Sci. 282, 119791 Pubmed Life Sci

Zhao G, Qi L, Wang Y, Li X, Li Q, Tang X, Wang X and Wu C. Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen. (2021) Ecotoxicol Environ Saf. 222, 112529 Pubmed Ecotoxicol Environ Saf

Yang X, Wang X, Gao D, Zhang Y, Chen X, Xia Q, Jin M, Sun C, He Q, Wang R and Liu K. Developmental toxicity caused by sanguinarine in zebrafish embryos via regulating oxidative stress, apoptosis and wnt pathways. (2021) Toxicol Lett. 350, 71-80 Pubmed Toxicol Lett

Liang H, Wu L, Hamunjo Chama MK, Ge X, Ren M, Chen X, Pan L and Xia D. Culture salinity modulates Nrf2 antioxidant signaling pathway and immune response of juvenile Genetically Improved Farmed Tilapia (GIFT) (Oreochromis niloticus) under different dietary protein levels. (2021) Fish Shellfish Immunol. 117, 220-227 Pubmed Fish Shellfish Immunol

Paiboonrungruang C, Simpson E, Xiong Z, Huang C, Li J, Li Y and Chen X. Development of targeted therapy of NRF2 esophageal squamous cell carcinoma. (2021) Cell Signal. 86, 110105 Pubmed Cell Signal PMC Article

Brasil FB, de Almeida FJS, Luckachaki MD, Dall'Oglio EL and de Oliveira MR. Suppression of Mitochondria-Related Bioenergetics Collapse and Redox Impairment by Tanshinone I, a Diterpenoid Found in Salvia miltiorrhiza Bunge (Danshen), in the Human Dopaminergic SH-SY5Y Cell Line Exposed to Chlorpyrifos. (2021) Neurotox Res. 39, 1495-1510 Pubmed Neurotox Res

Li Y, Zeng J, Tian YH, Hou Y, Da H, Fang J and Gao K. Isolation, identification, and activity evaluation of diterpenoid alkaloids from Aconitum sinomontanum. (2021) Phytochemistry. 190, 112880 Pubmed Phytochemistry

Chen L, Zhang WL, Xie DQ and Jia W. Sulforaphane alleviates hepatic ischemia-reperfusion injury through promoting the activation of Nrf-2/HO-1 signaling. (2021) Transpl Immunol. 68, 101439 Pubmed Transpl Immunol

Wang Z, Wang L, Jiang R, Li C, Chen X, Xiao H, Hou J, Hu L, Huang C and Wang Y. Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signaling. (2021) Free Radic Biol Med. 174, 182-194 Pubmed Free Radic Biol Med

Ma Y, Li S, Ye S, Tang S, Hu D, Wei L and Xiao F. Hexavalent chromium inhibits the formation of neutrophil extracellular traps and promotes the apoptosis of neutrophils via AMPK signaling pathway. (2021) Ecotoxicol Environ Saf. 223, 112614 Pubmed Ecotoxicol Environ Saf

Li L, Zhang Q, Zhang X, Xu X, Wang X, Huang X, Wang T, Jiang Z, Xiao L, Zhang L and Sun L. Protective effects of Nrf2 against sepsis-induced hepatic injury. (2021) Life Sci. 282, 119807 Pubmed Life Sci

Wen L, Yang QH, Ma XL, Li T, Xiao S and Sun CF. Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway. (2021) Int Immunopharmacol. 99, 107993 Pubmed Int Immunopharmacol

Fu J, Xu M, Xu L, Ni H, Zhao B, Ni C, Huang M, Zhu J, Luo G and Yao M. Sulforaphane alleviates hyperalgesia and enhances analgesic potency of morphine in rats with cancer-induced bone pain. (2021) Eur J Pharmacol. 909, 174412 Pubmed Eur J Pharmacol

Skowron MA, Oing C, Bremmer F, Ströbel P, Murray MJ, Coleman N, Amatruda JF, Honecker F, Bokemeyer C, Albers P and Nettersheim D. The developmental origin of cancers defines basic principles of cisplatin resistance. (2021) Cancer Lett. 519, 199-210 Pubmed Cancer Lett

Zhao J, Xiao X, Li Y, Gao X, Zhang X, Liu Z, Yi Y, Fu X, Wang H, Guan Y, Xia X, Zhang W and Huang J. The prevalence of HLA-I LOH in Chinese pan-cancer patients and genomic features of patients harboring HLA-I LOH. (2021) Hum Mutat. 42, 1254-1264 Pubmed Hum Mutat

Kalyankumarraju M, Puppala ER, Ahmed S, Jagadeesh Kumar G, Tene K, N P S, Sahu BD, Barua CC and Naidu VGM. Zanthoxylum alatum Roxb. seed extract ameliorates stress aggravated DSS-induced ulcerative colitis in mice: Plausible role on NF-κB signaling axis. (2021) J Ethnopharmacol. 279, 114385 Pubmed J Ethnopharmacol

Grattarola M, Cucci MA, Roetto A, Dianzani C, Barrera G and Pizzimenti S. Post-translational down-regulation of Nrf2 and YAP proteins, by targeting deubiquitinases, reduces growth and chemoresistance in pancreatic cancer cells. (2021) Free Radic Biol Med. 174, 202-210 Pubmed Free Radic Biol Med

Aydin Y, Chedid M, Chava S, Danielle Williams D, Liu S, Hagedorn CH, Sumitran-Holgersson S, Reiss K, Moroz K, Lu H, Balart LA and Dash S. Retraction Note: Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture. (2021) Sci Rep. 11, 17779 Pubmed Sci Rep

Liu H, Zhu S, Han W, Cai Y and Liu C. DMEP induces mitochondrial damage regulated by inhibiting Nrf2 and SIRT1/PGC-1α signaling pathways in HepG2 cells. (2021) Ecotoxicol Environ Saf. 221, 112449 Pubmed Ecotoxicol Environ Saf

Lalrinzuali K, Vabeiryureilai M and Jagetia GC. Sonapatha (Oroxylum indicum) mediates cytotoxicity in cultured HeLa cells by inducing apoptosis and suppressing NF-κB, COX-2, RASSF7 and NRF2. (2021) Bioorg Chem. 114, 105126 Pubmed Bioorg Chem

Baranwal A, Aggarwal P, Rai A and Kumar N. Pharmacological actions and underlying mechanisms of Catechin: A review. (2021) Mini Rev Med Chem. Pubmed Mini Rev Med Chem

Wang Y, Chang W, Li X, Jiang Z, Zhou D, Feng Y, Li B, Chen G and Li N. Apigenin exerts chemopreventive effects on lung injury induced by SiO nanoparticles through the activation of Nrf2. (2021) J Nat Med. Pubmed J Nat Med

Cao L, Zhao J, Ma L, Chen J, Xu J, Rahman SU, Feng S, Li Y, Wu J and Wang X. Lycopene attenuates zearalenone-induced oxidative damage of piglet sertoli cells through the nuclear factor erythroid-2 related factor 2 signaling pathway. (2021) Ecotoxicol Environ Saf. 225, 112737 Pubmed Ecotoxicol Environ Saf

Deng N, Jiang H, Wu P, Yang Q, Li S, Li J, Wang X, Han B, Han B, Lv Z and Zhang Z. Inhibition of the Nrf2/p38MAPK pathway involved in deltamethrin-induced apoptosis and fibrosis in quail kidney. (2021) Food Chem Toxicol. 155, 112382 Pubmed Food Chem Toxicol

Alshammari GM, Al-Qahtani WH, AlFaris NA, Albekairi NA, Alqahtani S, Eid R, Yagoub AEA, Al-Harbi LN and Yahya MA. Quercetin alleviates cadmium chloride-induced renal damage in rats by suppressing endoplasmic reticulum stress through SIRT1-dependent deacetylation of Xbp-1s and eIF2α. (2021) Biomed Pharmacother. 141, 111862 Pubmed Biomed Pharmacother

Pahlke G, Ahlberg K, Oertel A, Janson-Schaffer T, Grabher S, Mock HP, Matros A and Marko D. Antioxidant Effects of Elderberry Anthocyanins in Human Colon Carcinoma Cells: A Study on Structure-Activity Relationships. (2021) Mol Nutr Food Res. 65, e2100229 Pubmed Mol Nutr Food Res

Torrente L and DeNicola GM. Targeting NRF2 and Its Downstream Processes: Opportunities and Challenges. (2021) Annu Rev Pharmacol Toxicol. Pubmed Annu Rev Pharmacol Toxicol

Zhang Y, Wang O, Ma N, Yi J, Mi H and Cai S. The preventive effect and underlying mechanism of Mill. fruits on dextran sulphate sodium-induced ulcerative colitis in mice. (2021) Food Funct. Pubmed Food Funct

Liang Z, Zhao W, Li X, Wang L, Meng L and Yu R. Cisplatin synergizes with PRLX93936 to induce ferroptosis in non-small cell lung cancer cells. (2021) Biochem Biophys Res Commun. 569, 79-85 Pubmed Biochem Biophys Res Commun

Zgorzynska E, Dziedzic B and Walczewska A. An Overview of the Nrf2/ARE Pathway and Its Role in Neurodegenerative Diseases. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci

Da Silveira AR, Rosa ÉVF, Sari MHM, Sampaio TB, Dos Santos JT, Jardim NS, Müller SG, Oliveira MS, Nogueira CW and Furian AF. Therapeutic potential of beta-caryophyllene against aflatoxin B1-Induced liver toxicity: Biochemical and molecular insights in rats. (2021) Chem Biol Interact. 109635 Pubmed Chem Biol Interact

Younis NS, Elsewedy HS, Soliman WE, Shehata TM and Mohamed ME. Geraniol isolated from lemon grass to mitigate doxorubicin-induced cardiotoxicity through Nrf2 and NF-κB signaling. (2021) Chem Biol Interact. 347, 109599 Pubmed Chem Biol Interact

Chen SJ, Hseu YC, Gowrisankar YV, Chung YT, Zhang YZ, Way TD and Yang HL. The anti-melanogenic effects of 3-O-ethyl ascorbic acid via Nrf2-mediated α-MSH inhibition in UVA-irradiated keratinocytes and autophagy induction in melanocytes. (2021) Free Radic Biol Med. 173, 151-169 Pubmed Free Radic Biol Med

Mineo S, Takahashi N, Yamada-Hara M, Tsuzuno T, Aoki-Nonaka Y and Tabeta K. Rice bran-derived protein fractions enhance sulforaphane-induced anti-oxidative activity in gingival epithelial cells. (2021) Arch Oral Biol. 129, 105215 Pubmed Arch Oral Biol

Joshi A, Upadhyay KK, Vohra A, Shirsath K and Devkar R. Melatonin induces Nrf2-HO-1 reprogramming and corrections in hepatic core clock oscillations in Non-alcoholic fatty liver disease. (2021) FASEB J. 35, e21803 Pubmed FASEB J

Fu J, Ni C, Ni HD, Xu LS, He QL, Pan H, Huang DD, Sun YB, Luo G, Liu MJ and Yao M. Spinal Nrf2 translocation may inhibit neuronal NF-κB activation and alleviate allodynia in a rat model of bone cancer pain. (2021) J Neurochem. 158, 1110-1130 Pubmed J Neurochem

Niu LT, Wang YQ, Wong CCL, Gao SX, Mo XD and Huang XJ. Targeting IFN-γ-inducible lysosomal thiol reductase overcomes chemoresistance in AML through regulating the ROS-mediated mitochondrial damage. (2021) Transl Oncol. 14, 101159 Pubmed Transl Oncol PMC Article

Dempke WCM and Reck M. KEAP1/NRF2 (NFE2L2) mutations in NSCLC - Fuel for a superresistant phenotype?. (2021) Lung Cancer. 159, 10-17 Pubmed Lung Cancer

Agha KA, Ibrahim TS, Elsherbiny NM, El-Sherbiny M, Abdel-Aal EH, Abdel-Samii ZK and Abo-Dya NE. Design, synthesis and pharmacological screening of novel renoprotective methionine-based peptidomimetics: Amelioration of cisplatin-induced nephrotoxicity. (2021) Bioorg Chem. 114, 105100 Pubmed Bioorg Chem

Marderstein AR, Kulm S, Peng C, Tamimi R, Clark AG and Elemento O. A polygenic-score-based approach for identification of gene-drug interactions stratifying breast cancer risk. (2021) Am J Hum Genet. 108, 1752-1764 Pubmed Am J Hum Genet

Yu J, Yang Y, Li S and Meng P. Salinomycin triggers prostate cancer cell apoptosis by inducing oxidative and endoplasmic reticulum stress via suppressing Nrf2 signaling. (2021) Exp Ther Med. 22, 946 Pubmed Exp Ther Med PMC Article

Sanches LJ, Marinello PC, Brito WADS, Lopes NMD, Luiz RC, Cecchini R and Cecchini AL. Metformin pretreatment reduces effect to dacarbazine and suppresses melanoma cell resistance. (2021) Cell Biol Int. Pubmed Cell Biol Int

Tentscher PR, Escher BI, Schlichting R, König M, Bramaz N, Schirmer K and von Gunten U. Toxic effects of substituted p-benzoquinones and hydroquinones in in vitro bioassays are altered by reactions with the cell assay medium. (2021) Water Res. 202, 117415 Pubmed Water Res

Song Q, Peng S, Sun Z, Heng X and Zhu X. Temozolomide Drives Ferroptosis via a DMT1-Dependent Pathway in Glioblastoma Cells. (2021) Yonsei Med J. 62, 843-849 Pubmed Yonsei Med J PMC Article

Sun W, Shen Y, Xiao H and Li H. Resveratrol attenuates rotenone-induced inflammation and oxidative stress via STAT1 and Nrf2/Keap1/SLC7A11 pathway in a microglia cell line. (2021) Pathol Res Pract. 225, 153576 Pubmed Pathol Res Pract

Lee SC, Jee SC, Kim M, Kim S, Shin MK, Kim Y and Sung JS. Curcumin Suppresses the Lipid Accumulation and Oxidative Stress Induced by Benzo[a]pyrene Toxicity in HepG2 Cells. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

He C, Buongiorno LP, Wang W, Tang JCY, Miceli N, Taviano MF, Shan Y and Bao Y. The Inhibitory Effect of Sulforaphane on Bladder Cancer Cell Depends on GSH Depletion-Induced by Nrf2 Translocation. (2021) Molecules. 26, Pubmed Molecules PMC Article

Niederkorn M, Ishikawa C, M Hueneman K, Bartram J, Stepanchick E, R Bennett J, E Culver-Cochran A, Bolanos LC, Uible E, Choi K, Wunderlich M, Perentesis JP, M Chlon T, Filippi MD and Starczynowski DT. The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia. (2021) Leukemia. Pubmed Leukemia

Lee W, Sim H, Choi YJ, Seo JY, Yun MY, Song GY and Bae JS. The Decursin Analog, CYJ-27, Suppresses Inflammation Via the Downregulation of NF-B and STAT-1. (2021) J Med Food. 24, 852-859 Pubmed J Med Food

Li F, Aljahdali IAM, Zhang R, Nastiuk KL, Krolewski JJ and Ling X. Kidney cancer biomarkers and targets for therapeutics: survivin (BIRC5), XIAP, MCL-1, HIF1α, HIF2α, NRF2, MDM2, MDM4, p53, KRAS and AKT in renal cell carcinoma. (2021) J Exp Clin Cancer Res. 40, 254 Pubmed J Exp Clin Cancer Res PMC Article

Qiu P, Hou W, Wang H, Lei KKW, Wang S, Chen W, Pardeshi LA, Prothro K, Shukla Y, Su SSM, Schrump DS, Chen Q, Deng CX, Xu X and Wang R. Sirt1 deficiency upregulates glutathione metabolism to prevent hepatocellular carcinoma initiation in mice. (2021) Oncogene. Pubmed Oncogene

Sayed AM, Hassanein EHM, Ali FEM, Omar ZMM, Rashwan EK, Mohammedsaleh ZM and Abd El-Ghafar OAM. Regulation of Keap-1/Nrf2/AKT and iNOS/NF-κB/TLR4 signals by apocynin abrogated methotrexate-induced testicular toxicity: Mechanistic insights and computational pharmacological analysis. (2021) Life Sci. 284, 119911 Pubmed Life Sci

Zhen X, Jindong L, Yang Z, Yashi R, Wei G, Wei J, Wei Z and Sudong L. Activation of Nrf2 Pathway by Dimethyl Fumarate Attenuates Renal Ischemia-Reperfusion Injury. (2021) Transplant Proc. Pubmed Transplant Proc

Zakria M, Ahmad N, Al Kury LT, Alattar A, Uddin Z, Siraj S, Ullah S, Alshaman R, Khan MI and Shah FA. Melatonin rescues the mice brain against cisplatin-induced neurodegeneration, an insight into antioxidant and anti-inflammatory effects. (2021) Neurotoxicology. 87, 1-10 Pubmed Neurotoxicology

Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J and Zhong C. Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer. (2021) J Exp Clin Cancer Res. 40, 266 Pubmed J Exp Clin Cancer Res PMC Article

Pallio G, D'Ascola A, Cardia L, Mannino F, Bitto A, Minutoli L, Picciolo G, Squadrito V, Irrera N, Squadrito F and Altavilla D. MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci PMC Article

Baer-Dubowska W, Narożna M and Krajka-Kuźniak V. Anti-Cancer Potential of Synthetic Oleanolic Acid Derivatives and Their Conjugates with NSAIDs. (2021) Molecules. 26, Pubmed Molecules PMC Article

Zhao Y, Lu J, Mao A, Zhang R and Guan S. Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway. (2021) J Agric Food Chem. 69, 9671-9683 Pubmed J Agric Food Chem

Liu WC, Zhu YR, Zhao ZH, Jiang P and Yin FQ. Effects of Dietary Supplementation of Algae-Derived Polysaccharides on Morphology, Tight Junctions, Antioxidant Capacity and Immune Response of Duodenum in Broilers under Heat Stress. (2021) Animals (Basel). 11, Pubmed Animals (Basel) PMC Article

Cong P, Wang T, Tong C, Liu Y, Shi L, Mao S, Shi X, Jin H, Liu Y and Hou M. Resveratrol ameliorates thoracic blast exposure-induced inflammation, endoplasmic reticulum stress and apoptosis in the brain through the Nrf2/Keap1 and NF-κB signaling pathway. (2021) Injury. Pubmed Injury

Feng L, Zhao K, Sun L, Yin X, Zhang J, Liu C and Li B. SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis. (2021) J Transl Med. 19, 367 Pubmed J Transl Med PMC Article

Hassanein EHM, Ahmed MA, Sayed AM, Rashwan EK, Abd El-Ghafar OAM and Mahmoud AM. Edaravone mitigates hemorrhagic cystitis by modulating Nrf2, TLR-4/NF-κB, and JAK1/STAT3 signaling in cyclophosphamide-intoxicated rats. (2021) J Biochem Mol Toxicol. e22889 Pubmed J Biochem Mol Toxicol

Yahyazadeh R, Baradaran Rahimi V, Yahyazadeh A, Mohajeri SA and Askari VR. Promising effects of gingerol against toxins: A review article. (2021) Biofactors. Pubmed Biofactors

He L, Guo C, Peng C and Li Y. Advances of natural activators for Nrf2 signaling pathway on cholestatic liver injury protection: A review. (2021) Eur J Pharmacol. 174447 Pubmed Eur J Pharmacol

Calderwood SK, Borges TJ, Eguchi T, Lang BJ, Murshid A, Okusha Y and Prince TL. Extracellular Hsp90 and protection of neuronal cells through Nrf2. (2021) Biochem Soc Trans. Pubmed Biochem Soc Trans

Lyu L, Chen Z and McCarty N. TRIM44 links the UPS to SQSTM1/p62-dependent aggrephagy and removing misfolded proteins. (2021) Autophagy. 1-16 Pubmed Autophagy

Zhang XX, Jin JW, Liu CH, Zhou M, He YX, Wang F and Liu FZ. [Effect of Nrf2/HO-1 signaling pathway in intestinal protection by Sishen Pills against ulcerative colitis in mice]. (2021) Zhongguo Zhong Yao Za Zhi. 46, 4187-4192 Pubmed Zhongguo Zhong Yao Za Zhi

Lv Z, Shen J, Gao X, Ruan Y, Ling J, Sun R, Dai J, Fan H, Cheng X and Cao P. Herbal formula Huangqi Guizhi Wuwu decoction attenuates paclitaxel-related neurotoxicity via inhibition of inflammation and oxidative stress. (2021) Chin Med. 16, 76 Pubmed Chin Med PMC Article

Zhang H, Wang Z, Hu K and Liu H. Downregulation of long noncoding RNA SNHG7 protects against inflammation and apoptosis in Parkinson's disease model by targeting the miR-425-5p/TRAF5/NF-κB axis. (2021) J Biochem Mol Toxicol. e22867 Pubmed J Biochem Mol Toxicol

. Bayer's Vividion Buy Targets Undruggable Proteins. (2021) Cancer Discov. Pubmed Cancer Discov

Lee S, Ha J, Park J, Kang E, Jeon SH, Han SB, Ningsih S, Paik JH and Cho S. Antioxidant and Anti-Inflammatory Effects of (Blume) Leaf Methanol Extracts through the Regulation of Nrf2 and TAK1. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Chen B, Zhu D, Xie C, Shi Y, Ni L, Zhang H, Li S, Lu J, Xiao J, Xia W, Huang C and Wang X. 18β-Glycyrrhetinic acid inhibits IL-1β-induced inflammatory response in mouse chondrocytes and prevents osteoarthritic progression by activating Nrf2. (2021) Food Funct. Pubmed Food Funct

Shen P, Han L, Chen G, Cheng Z and Liu Q. Emodin Attenuates Acetaminophen-Induced Hepatotoxicity via the cGAS-STING Pathway. (2021) Inflammation. Pubmed Inflammation

Otsuka S, Setoyama K, Takada S, Nakanishi K, Terashi T, Norimatsu K, Tani A, Sakakima H, Maruyama I, Tancharoen S, Tanaka E and Kikuchi K. Preconditioning Exercise in Rats Attenuates Early Brain Injury Resulting from Subarachnoid Hemorrhage by Reducing Oxidative Stress, Inflammation, and Neuronal Apoptosis. (2021) Mol Neurobiol. Pubmed Mol Neurobiol

Ren X, Li Y, Zhou Y, Hu W, Yang C, Jing Q, Zhou C, Wang X, Hu J, Wang L, Yang J, Wang H, Xu H, Li H, Tong X, Wang Y and Du J. Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis. (2021) Redox Biol. 46, 102122 Pubmed Redox Biol PMC Article

Vyas A, Harbison RA, Faden DL, Kubik M, Palmer D, Zhang Q, Osmanbeyoglu HU, Méndez E and Duvvuri U. Recurrent human papillomavirus-related head and neck cancer undergoes metabolic re-programming and is driven by oxidative phosphorylation. (2021) Clin Cancer Res. Pubmed Clin Cancer Res

Kim SL, Choi HS, Ko YC, Yun BS and Lee DS. 5-Hydroxymaltol Derived from Beetroot Juice through Fermentation Suppresses Inflammatory Effect and Oxidant Stress via Regulating NF-kB, MAPKs Pathway and NRF2/HO-1 Expression. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Yu J, Li W, Xiao X, Huang Q, Yu J, Yang Y, Han T, Zhang D and Niu X. (-)-Epicatechin gallate blocks the development of atherosclerosis by regulating oxidative stress and . (2021) Food Funct. Pubmed Food Funct

Tanaka Y, Hamada S, Matsumoto R, Taguchi K, Yamamoto M and Masamune A. Nrf2 expression in pancreatic stellate cells promotes progression of cancer. (2021) Am J Physiol Gastrointest Liver Physiol. Pubmed Am J Physiol Gastrointest Liver Physiol

Xu Z, Li X, Li X, Gao Y and Mi X. Dioscin attenuates lipopolysaccharide-induced inflammatory myocardial injury through oxidative stress-related pathway. (2021) Ann Palliat Med. 10, 8827-8836 Pubmed Ann Palliat Med

Shati AA and El-Kott AF. Resolvin D1 protects against cadmium chloride-induced memory loss and hippocampal damage in rats: A comparison with docosahexaenoic acid. (2021) Hum Exp Toxicol. 9603271211038739 Pubmed Hum Exp Toxicol

Chen L, Jin XH, Luo J, Duan JL, Cai MY, Chen JW, Feng ZH, Guo AM, Wang FW and Xie D. ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma. (2021) Oncogene. Pubmed Oncogene

Awny MM, Al-Mokaddem AK and Ali BM. Mangiferin mitigates di-(2-ethylhexyl) phthalate-induced testicular injury in rats by modulating oxidative stress-mediated signals, inflammatory cascades, apoptotic pathways, and steroidogenesis. (2021) Arch Biochem Biophys. 711, 108982 Pubmed Arch Biochem Biophys

Zhang S, Zhao J and Ma W. Circ-Sirt1 inhibits proliferation, induces apoptosis, and ameliorates inflammation in human rheumatoid arthritis fibroblast-like synoviocytes. (2021) Autoimmunity. 1-12 Pubmed Autoimmunity

Papierska K, Krajka-Kuźniak V, Paluszczak J, Kleszcz R, Skalski M, Studzińska-Sroka E and Baer-Dubowska W. Lichen-Derived Depsides and Depsidones Modulate the Nrf2, NF-κB and STAT3 Signaling Pathways in Colorectal Cancer Cells. (2021) Molecules. 26, Pubmed Molecules PMC Article

Brasil FB, de Almeida FJS, Luckachaki MD, Dall'Oglio EL and de Oliveira MR. Pinocembrin pretreatment counteracts the chlorpyrifos-induced HO-1 downregulation, mitochondrial dysfunction, and inflammation in the SH-SY5Y cells. (2021) Metab Brain Dis. Pubmed Metab Brain Dis

Scuto M, Trovato Salinaro A, Caligiuri I, Ontario ML, Greco V, Sciuto N, Crea R, Calabrese EJ, Rizzolio F, Canzonieri V and Calabrese V. Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology. (2021) Mech Ageing Dev. 199, 111551 Pubmed Mech Ageing Dev

Hou Y, Li J, Wu JC, Wu QX and Fang J. Activation of Cellular Antioxidant Defense System by Naturally Occurring Dibenzopyrone Derivatives Confers Neuroprotection against Oxidative Insults. (2021) ACS Chem Neurosci. 12, 2798-2809 Pubmed ACS Chem Neurosci

Chew LY, Zhang H, He J and Yu F. The Nrf2-Keap1 pathway is activated by steroid hormone signaling to govern neuronal remodeling. (2021) Cell Rep. 36, 109466 Pubmed Cell Rep

Mishra R, Nawas AF and Mendelson CR. Role of NRF2 in immune modulator expression in developing lung. (2021) FASEB J. 35, e21758 Pubmed FASEB J

Iahtisham-Ul-Haq , Khan S, Awan KA and Iqbal MJ. Sulforaphane as a potential remedy against cancer: Comprehensive mechanistic review. (2021) J Food Biochem. e13886 Pubmed J Food Biochem

Liu WC, Ou BH, Liang ZL, Zhang R and Zhao ZH. Algae-derived polysaccharides supplementation ameliorates heat stress-induced impairment of bursa of Fabricius via modulating NF-κB signaling pathway in broilers. (2021) Poult Sci. 100, 101139 Pubmed Poult Sci PMC Article

Ryšavá A, Vostálová J and Rajnochová Svobodová A. Effect of ultraviolet radiation on the Nrf2 signaling pathway in skin cells. (2021) Int J Radiat Biol. 1-21 Pubmed Int J Radiat Biol

Chun KS, Raut PK, Kim DH and Surh YJ. Role of chemopreventive phytochemicals in NRF2-mediated redox homeostasis in humans. (2021) Free Radic Biol Med. 172, 699-715 Pubmed Free Radic Biol Med

Krajka-Kuźniak V and Baer-Dubowska W. Modulation of Nrf2 and NF-κB Signaling Pathways by Naturally Occurring Compounds in Relation to Cancer Prevention and Therapy. Are Combinations Better Than Single Compounds?. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci PMC Article

Emanuele S, Celesia A, D'Anneo A, Lauricella M, Carlisi D, De Blasio A and Giuliano M. The Good and Bad of Nrf2: An Update in Cancer and New Perspectives in COVID-19. (2021) Int J Mol Sci. 22, Pubmed Int J Mol Sci PMC Article

Tang G, Xu Y, Zhang C, Wang N, Li H and Feng Y. Green Tea and Epigallocatechin Gallate (EGCG) for the Management of Nonalcoholic Fatty Liver Diseases (NAFLD): Insights into the Role of Oxidative Stress and Antioxidant Mechanism. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Chen SJ, Lin TB, Peng HY, Lin CH, Lee AS, Liu HJ, Li CC and Tseng KW. Protective Effects of Fucoxanthin Dampen Pathogen-Associated Molecular Pattern (PAMP) Lipopolysaccharide-Induced Inflammatory Action and Elevated Intraocular Pressure by Activating Nrf2 Signaling and Generating Reactive Oxygen Species. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Guzmán Mendoza NA, Homma K, Osada H, Toda E, Ban N, Nagai N, Negishi K, Tsubota K and Ozawa Y. Neuroprotective Effect of 4-Phenylbutyric Acid against Photo-Stress in the Retina. (2021) Antioxidants (Basel). 10, Pubmed Antioxidants (Basel) PMC Article

Narożna M, Krajka-Kuźniak V, Bednarczyk-Cwynar B, Kucińska M, Kleszcz R, Kujawski J, Piotrowska-Kempisty H, Plewiński A, Murias M and Baer-Dubowska W. Conjugation of Diclofenac with Novel Oleanolic Acid Derivatives Modulate Nrf2 and NF-κB Activity in Hepatic Cancer Cells and Normal Hepatocytes Leading to Enhancement of Its Therapeutic and Chemopreventive Potential. (2021) Pharmaceuticals (Basel). 14, Pubmed Pharmaceuticals (Basel) PMC Article

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