Clinical Trials & Research

English: Graph of Nrf2 publications (pubmed se...

English: Graph of Nrf2 publications (pubmed search) by year (Photo credit: Wikipedia)

There are currently over 2300 articles (peer reviewed clinical reviews and studies) on on the topic of NRF2 Activation.

There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to and type in the name of their product.

Pubmed is a website operated by the National Institute of Health (NIH).  PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources.

Last 200 NRF-2 Studies published on Pubmed

Li LH, Peng WN, Deng Y, Li JJ and Tian XR. Action of trichostatin A on Alzheimer's disease-like pathological changes in SH-SY5Y neuroblastoma cells. (2020) Neural Regen Res. 15, 293-301 Pubmed Neural Regen Res
Kalvala AK, Yerra VG and Kumar A. LONP1 induction by SRT1720 attenuates mitochondrial dysfunction against high glucose induced neurotoxicity in PC12 cells. (2020) Toxicol In Vitro. 62, 104695 Pubmed Toxicol In Vitro
Jabbarzadeh Kaboli P, Afzalipour Khoshkbejari M, Mohammadi M, Abiri A, Mokhtarian R, Vazifemand R, Amanollahi S, Yazdi Sani S, Li M, Zhao Y, Wu X, Shen J, Cho CH and Xiao Z. Targets and mechanisms of sulforaphane derivatives obtained from cruciferous plants with special focus on breast cancer - contradictory effects and future perspectives. (2020) Biomed. Pharmacother.. 121, 109635 Pubmed Biomed. Pharmacother.
Ferraro SA, Domingo MG, Etcheverrito A, Olmedo DG and Tasat DR. Neurotoxicity mediated by oxidative stress caused by titanium dioxide nanoparticles in human neuroblastoma (SH-SY5Y) cells. (2020) J Trace Elem Med Biol. 57, 126413 Pubmed J Trace Elem Med Biol
Bose P, Siddique MUM, Acharya R, Jayaprakash V, Sinha BN, Lapenna A and Pattanayak SP. Quinazolinone derivative BNUA-3 ameliorated [NDEA+2-AAF]-induced liver carcinogenesis in SD rats by modulating AhR-CYP1B1-Nrf2-Keap1 pathway. (2020) Clin. Exp. Pharmacol. Physiol.. 47, 143-157 Pubmed Clin. Exp. Pharmacol. Physiol.
Sun S, Du Y, Yin C, Suo X, Wang R, Xia R and Zhang X. Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways. (2019) BMC Complement Altern Med. 19, 343 Pubmed BMC Complement Altern Med
Lin ZH, Chan YF, Pan MH, Tung YC and Su ZY. Aged Citrus Peel (Chenpi) Prevents Acetaminophen-Induced Hepatotoxicity by Epigenetically Regulating Nrf2 Pathway. (2019) Am. J. Chin. Med.. 1-19 Pubmed Am. J. Chin. Med.
Griñán-Ferré C, Marsal-García L, Bellver-Sanchis A, Kondengaden SM, Turga RC, Vázquez S and Pallàs M. Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer's disease mouse model. (2019) Aging (Albany NY). 11, Pubmed Aging (Albany NY)
Wang ML, Zhong QY, Lin BQ, Liu YH, Huang YF, Chen Y, Yuan J, Su ZR and Zhan JY. Andrographolide sodium bisulfate attenuates UV‑induced photo‑damage by activating the keap1/Nrf2 pathway and downregulating the NF‑κB pathway in HaCaT keratinocytes. (2019) Int. J. Mol. Med.. Pubmed Int. J. Mol. Med.
Hammad A, Namani A, Elshaer M, Wang XJ and Tang X. "NRF2 addiction" in lung cancer cells and its impact on cancer therapy. (2019) Cancer Lett.. 467, 40-49 Pubmed Cancer Lett.
Huang XT, Liu W, Zhou Y, Hao CX, Zhou Y, Zhang CY, Sun CC, Luo ZQ and Tang SY. Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner. (2019) Int. J. Mol. Med.. 44, 2213-2222 Pubmed Int. J. Mol. Med. PMC Article
Han H, Wang H, Du Y and Gao L. Grape Seed Procyanidins Attenuates Cisplatin-induced Human Embryonic Renal Cell Cytotoxicity by Modulating Heme Oxygenase-1 in Vitro. (2019) Cell Biochem. Biophys.. 77, 367-377 Pubmed Cell Biochem. Biophys.
Guo H, Xu J, Zheng Q, He J, Zhou W, Wang K, Huang X, Fan Q, Ma J, Cheng J, Mei W, Xing R and Cai R. NRF2 SUMOylation promotes de novo serine synthesis and maintains HCC tumorigenesis. (2019) Cancer Lett.. 466, 39-48 Pubmed Cancer Lett.
Ali J, Khan AU, Shah FA, Ali H, Islam SU, Kim YS and Khan S. Mucoprotective effects of Saikosaponin-A in 5-fluorouracil-induced intestinal mucositis in mice model. (2019) Life Sci.. 239, 116888 Pubmed Life Sci.
Albert AE, Adua SJ, Cai WL, Arnal-Estapé A, Cline GW, Liu Z, Zhao M, Cao PD, Mariappan M and Nguyen DX. Adaptive Protein Translation by the Integrated Stress Response Maintains the Proliferative and Migratory Capacity of Lung Adenocarcinoma Cells. (2019) Mol. Cancer Res.. 17, 2343-2355 Pubmed Mol. Cancer Res.
Zhang Z, Jiang D, Wang C, Garzotto M, Kopp R, Wilmot B, Thuillier P, Dang A, Palma A, Farris PE and Shannon J. Polymorphisms in oxidative stress pathway genes and prostate cancer risk. (2019) Cancer Causes Control. 30, 1365-1375 Pubmed Cancer Causes Control
Hammad A, Zheng ZH, Gao Y, Namani A, Shi HF and Tang X. Identification of novel Nrf2 target genes as prognostic biomarkers in colitis-associated colorectal cancer in Nrf2-deficient mice. (2019) Life Sci.. 238, 116968 Pubmed Life Sci.
El-Naggar AM, Somasekharan SP, Wang Y, Cheng H, Negri GL, Pan M, Wang XQ, Delaidelli A, Rafn B, Cran J, Zhang F, Zhang H, Colborne S, Gleave M, Mandinova A, Kedersha N, Hughes CS, Surdez D, Delattre O, Wang Y, Huntsman DG, Morin GB and Sorensen PH. Class I HDAC inhibitors enhance YB-1 acetylation and oxidative stress to block sarcoma metastasis. (2019) EMBO Rep.. 20, e48375 Pubmed EMBO Rep.
Zhang HB, Tu XK, Chen Q and Shi SS. Propofol Reduces Inflammatory Brain Injury after Subarachnoid Hemorrhage: Involvement of PI3K/Akt Pathway. (2019) J Stroke Cerebrovasc Dis. 28, 104375 Pubmed J Stroke Cerebrovasc Dis
Hu L, Li H, Lee ED, Grandis JR, Bauman JE and Johnson DE. Gene targets of sulforaphane in head and neck squamous cell carcinoma. (2019) Mol Med Rep. 20, 5335-5344 Pubmed Mol Med Rep PMC Article
Dhar R, Zhang L, Li Y, Rana MN, Hu Z, Li Z, Cui H and Tang H. Electroacupuncture ameliorates cardiopulmonary bypass induced apoptosis in lung via ROS/Nrf2/NLRP3 inflammasome pathway. (2019) Life Sci.. 238, 116962 Pubmed Life Sci.
El-Shitany NA and Eid BG. Icariin modulates carrageenan-induced acute inflammation through HO-1/Nrf2 and NF-kB signaling pathways. (2019) Biomed. Pharmacother.. 120, 109567 Pubmed Biomed. Pharmacother.
Zhang J, Zhang Q, Liu G and Zhang N. Therapeutic potentials and mechanisms of the Chinese traditional medicine Danshensu. (2019) Eur. J. Pharmacol.. 864, 172710 Pubmed Eur. J. Pharmacol.
Wu C, Zhang H, Zhang J, Zhang H, Zeng Y, Fang S, Li P, Zhang Y, Lin X, Wang L, Xue Y and Guan M. Increased oxidative stress, inflammation and fibrosis in perirenal adipose tissue of patients with cortisol-producing adenoma. (2019) Adipocyte. 8, 347-356 Pubmed Adipocyte
Li Y, Darwish WS, Chen Z, Hui T, Wu Y, Hirotaka S, Chiba H and Hui SP. Identification of lead-produced lipid hydroperoxides in human HepG2 cells and protection using rosmarinic and ascorbic acids with a reference to their regulatory roles on Nrf2-Keap1 antioxidant pathway. (2019) Chem. Biol. Interact.. 314, 108847 Pubmed Chem. Biol. Interact.
Zhang XY, Jia YP, Zhao Q, Wang WY, Zhang Z, Li W and Sun LC. Ameliorative effect of acetylshikonin on cigarette smoke-induced lung inflammation in mice. (2019) J Asian Nat Prod Res. 1-17 Pubmed J Asian Nat Prod Res
Bailly C. Potential use of edaravone to reduce specific side effects of chemo-, radio- and immuno-therapy of cancers. (2019) Int. Immunopharmacol.. 77, 105967 Pubmed Int. Immunopharmacol.
Jaafaru MS, Nordin N, Rosli R, Shaari K, Bako HY, Saad N, Noor NM and Abdull Razis AF. Neuroprotective effects of glucomoringin-isothiocyanate against HO-Induced cytotoxicity in neuroblastoma (SH-SY5Y) cells. (2019) Neurotoxicology. 75, 89-104 Pubmed Neurotoxicology
Kahroba H, Shirmohamadi M, Hejazi MS and Samadi N. The Role of Nrf2 signaling in cancer stem cells: From stemness and self-renewal to tumorigenesis and chemoresistance. (2019) Life Sci.. 239, 116986 Pubmed Life Sci.
Yu Q, Xia Z, Liong EC and Tipoe GL. Chronic aerobic exercise improves insulin sensitivity and modulates Nrf2 and NF‑κB/IκBα pathways in the skeletal muscle of rats fed with a high fat diet. (2019) Mol Med Rep. 20, 4963-4972 Pubmed Mol Med Rep PMC Article
Peng N, Jin L, He A, Deng C and Wang X. Effect of sulphoraphane on newborn mouse cardiomyocytes undergoing ischaemia/reperfusion injury. (2019) Pharm Biol. 57, 753-759 Pubmed Pharm Biol PMC Article
Kandasamy M, Mak KK, Devadoss T, Thanikachalam PV, Sakirolla R, Choudhury H and Pichika MR. Construction of a novel quinoxaline as a new class of Nrf2 activator. (2019) BMC Chem. 13, 117 Pubmed BMC Chem PMC Article
Su R, Su W and Jiao Q. NGF protects neuroblastoma cells against β-amyloid-induced apoptosis via the Nrf2/HO-1 pathway. (2019) FEBS Open Bio. 9, 2063-2071 Pubmed FEBS Open Bio
Nam LB and Keum YS. Binding partners of NRF2: Functions and regulatory mechanisms. (2019) Arch. Biochem. Biophys.. 678, 108184 Pubmed Arch. Biochem. Biophys.
Szade A, Szade K, Nowak WN, Bukowska-Strakova K, Muchova L, Gońka M, Żukowska M, Cieśla M, Kachamakova-Trojanowska N, Rams-Baron M, Ratuszna A, Dulak J and Józkowicz A. Cobalt protoporphyrin IX increases endogenous G-CSF and mobilizes HSC and granulocytes to the blood. (2019) EMBO Mol Med. 11, e09571 Pubmed EMBO Mol Med
Towers CG and Thorburn A. Circumventing autophagy inhibition. (2019) Cell Cycle. 18, 3421-3431 Pubmed Cell Cycle
Zhang X, Wang Y, Li X, Yang A, Li Z and Wang D. The anti-carcinogenesis properties of erianin in the modulation of oxidative stress-mediated apoptosis and immune response in liver cancer. (2019) Aging (Albany NY). 11, 10284-10300 Pubmed Aging (Albany NY)
Montesano A, Senesi P, Vacante F, Mollica G, Benedini S, Mariotti M, Luzi L and Terruzzi I. L-Carnitine counteracts in vitro fructose-induced hepatic steatosis through targeting oxidative stress markers. (2019) J. Endocrinol. Invest.. Pubmed J. Endocrinol. Invest.
Sun Y, Zhou S, Guo H, Zhang J, Ma T, Zheng Y, Zhang Z and Cai L. Protective effects of sulforaphane on type 2 diabetes-induced cardiomyopathy via AMPK-mediated activation of lipid metabolic pathways and NRF2 function. (2019) Metab. Clin. Exp.. 102, 154002 Pubmed Metab. Clin. Exp.
Schultrich K, Henderson CJ, Braeuning A and Buhrke T. Correlation between 3-MCPD-induced organ toxicity and oxidative stress response in male mice. (2019) Food Chem. Toxicol.. 110957 Pubmed Food Chem. Toxicol.
Murray JR, de la Vega L, Hayes JD, Duan L and Penning TM. Induction of the Antioxidant Response by the Transcription Factor NRF2 Increases Bioactivation of the Mutagenic Air Pollutant 3-Nitrobenzanthrone in Human Lung Cells. (2019) Chem. Res. Toxicol.. Pubmed Chem. Res. Toxicol.
Lan J, Zheng J, Feng J and Peng W. Nrf2 mediates the antinociceptive activity of dexmedetomidine in an acute inflammatory visceral pain rat model by activating the NF-κB sensor. (2019) Cell Biochem. Funct.. Pubmed Cell Biochem. Funct.
Jang BS, Han W and Kim IA. Tumor mutation burden, immune checkpoint crosstalk and radiosensitivity in single-cell RNA sequencing data of breast cancer. (2019) Radiother Oncol. Pubmed Radiother Oncol
Ren J, Su D, Li L, Cai H, Zhang M, Zhai J, Li M, Wu X and Hu K. Anti-inflammatory effects of Aureusidin in LPS-stimulated RAW264.7 macrophages via suppressing NF-κB and activating ROS- and MAPKs-dependent Nrf2/HO-1 signaling pathways. (2019) Toxicol. Appl. Pharmacol.. 114846 Pubmed Toxicol. Appl. Pharmacol.
Chu Q, Jia R, Chen W, Liu Y, Li Y, Ye X, Jiang Y and Zheng X. Purified Tetrastigma hemsleyanum vines polysaccharide attenuates EC-induced toxicity in Caco-2 cells and Caenorhabditis elegans via DAF-16/FOXO pathway. (2019) Int. J. Biol. Macromol.. Pubmed Int. J. Biol. Macromol.
Kobayashi A and Waku T. New addiction to the NRF2-related factor NRF3 in cancer cells: Ubiquitin-independent proteolysis via the 20S proteasome. (2019) Cancer Sci.. Pubmed Cancer Sci.
Almeida M, Soares M, Ramalhinho AC, Moutinho JF, Breitenfeld L and Pereira L. The prognostic value of NRF2 in breast cancer patients: a systematic review with meta-analysis. (2019) Breast Cancer Res. Treat.. Pubmed Breast Cancer Res. Treat.
Bernardo PS, Guimarães GHC, De Faria FCC, Longo GMDC, Lopes GPF, Netto CD, Costa PRR and Maia RC. LQB‑118 compound inhibits migration and induces cell death in glioblastoma cells. (2019) Oncol. Rep.. Pubmed Oncol. Rep.
Ooi A. Advances in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) research. (2019) Semin. Cancer Biol.. Pubmed Semin. Cancer Biol.
Cho JH, Lee YM, Bae SH and Chou JY. Activation of tumor-promoting pathways implicated in hepatocellular adenoma/carcinoma, a long-term complication of glycogen storage disease type Ia. (2019) Biochem. Biophys. Res. Commun.. Pubmed Biochem. Biophys. Res. Commun.
Dwivedi DK and Jena GB. Diethylnitrosamine and thioacetamide-induced hepatic damage and early carcinogenesis in rats: Role of Nrf2 activator dimethyl fumarate and NLRP3 inhibitor glibenclamide. (2019) Biochem. Biophys. Res. Commun.. Pubmed Biochem. Biophys. Res. Commun.
Zimta AA, Cenariu D, Irimie A, Magdo L, Nabavi SM, Atanasov AG and Berindan-Neagoe I. The Role of Nrf2 Activity in Cancer Development and Progression. (2019) Cancers (Basel). 11, Pubmed Cancers (Basel)
Pellegatta S, Di Ianni N, Pessina S, Paterra R, Anghileri E, Eoli M and Finocchiaro G. ABCC3 Expressed by CD56 CD16 NK Cells Predicts Response in Glioblastoma Patients Treated with Combined Chemotherapy and Dendritic Cell Immunotherapy. (2019) Int J Mol Sci. 20, Pubmed Int J Mol Sci
Zhang X, Chu X, Gong X, Zhou H and Cai C. The expression of miR-125b in Nrf2-silenced A549 cells exposed to hyperoxia and its relationship with apoptosis. (2019) J. Cell. Mol. Med.. Pubmed J. Cell. Mol. Med.
Ashrafizadeh M, Ahmadi Z, Farkhondeh T and Samarghandian S. Back to Nucleus: Combating with Cadmium Toxicity Using Nrf2 Signaling Pathway as a Promising Therapeutic Target. (2019) Biol Trace Elem Res. Pubmed Biol Trace Elem Res
Yamaguchi Y, Kamai T, Higashi S, Murakami S, Arai K, Shirataki H and Yoshida KI. Nrf2 gene mutation and single nucleotide polymorphism rs6721961 of the Nrf2 promoter region in renal cell cancer. (2019) BMC Cancer. 19, 1137 Pubmed BMC Cancer PMC Article
Panigrahi DP, Bhol CS, R N, Nagini S, Patil S, Maiti TK and Bhutia SK. Abrus agglutinin inhibits oral carcinogenesis through inactivation of NRF2 signaling pathway. (2019) Int. J. Biol. Macromol.. Pubmed Int. J. Biol. Macromol.
Khiatah B, Qi M, Du W, T-Chen K, van Megen KM, Perez RG, Isenberg JS, Kandeel F, Roep BO, Ku HT and Al-Abdullah IH. Intra-pancreatic tissue-derived mesenchymal stromal cells: a promising therapeutic potential with anti-inflammatory and pro-angiogenic profiles. (2019) Stem Cell Res Ther. 10, 322 Pubmed Stem Cell Res Ther PMC Article
Qu H, Gao X, Wang ZY and Yi JJ. Comparative study on hepatoprotection of pine nut (Pinus koraiensis Sieb. et Zucc.) polysaccharide against different types of chemical-induced liver injury models in vivo. (2019) Int. J. Biol. Macromol.. Pubmed Int. J. Biol. Macromol.
Zhu T, Fang F, Sun D, Yang S, Zhang X, Yu X and Yang L. Piceatannol Inhibits P. acnes-Induced Keratinocyte Proliferation and Migration by Downregulating Oxidative Stress and the Inflammatory Response. (2019) Inflammation. Pubmed Inflammation
Londhe AM, Gadhe CG, Lim SM and Pae AN. Investigation of Molecular Details of Keap1-Nrf2 Inhibitors Using Molecular Dynamics and Umbrella Sampling Techniques. (2019) Molecules. 24, Pubmed Molecules
Mizumura K, Maruoka S, Shimizu T and Gon Y. Role of Nrf2 in the pathogenesis of respiratory diseases. (2019) Respir Investig. Pubmed Respir Investig
Wang J, Gao Y, Lin F, Han K and Wang X. Omentin-1 attenuates lipopolysaccharide (LPS)-induced U937 macrophages activation by inhibiting the TLR4/MyD88/NF-κB signaling. (2019) Arch. Biochem. Biophys.. 108187 Pubmed Arch. Biochem. Biophys.
Mussard E, Cesaro A, Lespessailles E, Legrain B, Berteina-Raboin S and Toumi H. Andrographolide, a Natural Antioxidant: An Update. (2019) Antioxidants (Basel). 8, Pubmed Antioxidants (Basel)
Lu Y, Hu P, Zhou H, Yang Z, Sun YU, Hoffman RM and Chen J. Double-negative T Cells Inhibit Proliferation and Invasion of Human Pancreatic Cancer Cells in Co-culture. (2019) Anticancer Res.. 39, 5911-5918 Pubmed Anticancer Res.
Wang Z, Zhang J, Li M, Kong L and Yu J. The expression of p-p62 and nuclear Nrf2 in esophageal squamous cell carcinoma and association with radioresistance. (2019) Thorac Cancer. Pubmed Thorac Cancer
Yang C, Gong J, Xu W, Liu Z and Cui D. Next-generation sequencing identified somatic alterations that may underlie the etiology of Chinese papillary thyroid carcinoma. (2019) Eur. J. Cancer Prev.. Pubmed Eur. J. Cancer Prev.
Wang T, Dai F, Li GH, Chen XM, Li YR, Wang SQ, Ren DM, Wang XN, Lou HX, Zhou B and Shen T. Trans-4,4'-dihydroxystilbene ameliorates cigarette smoke-induced progression of chronic obstructive pulmonary disease via inhibiting oxidative stress and inflammatory response. (2019) Free Radic. Biol. Med.. Pubmed Free Radic. Biol. Med.
Wang J, Lu Q, Cai J, Wang Y, Lai X, Qiu Y, Huang Y, Ke Q, Zhang Y, Guan Y, Wu H, Wang Y, Liu X, Shi Y, Zhang K, Wang M and Peng Xiang A. Nestin regulates cellular redox homeostasis in lung cancer through the Keap1-Nrf2 feedback loop. (2019) Nat Commun. 10, 5043 Pubmed Nat Commun PMC Article
Vaghefinezhad N, Farsani SF and Gharaghani S. In Silico Drug-Designing Studies on Sulforaphane Analogues: Pharmacophore Mapping, Molecular Docking and QSAR Modeling. (2019) Curr Drug Discov Technol. Pubmed Curr Drug Discov Technol
Li R, Jia Z and Zhu H. Regulation of Nrf2 Signaling. (2019) React Oxyg Species (Apex). 8, 312-322 Pubmed React Oxyg Species (Apex) PMC Article
Borella R, Forti L, Gibellini L, De Gaetano A, De Biasi S, Nasi M, Cossarizza A and Pinti M. Synthesis and Anticancer Activity of CDDO and CDDO-Me, Two Derivatives of Natural Triterpenoids. (2019) Molecules. 24, Pubmed Molecules
Luk ST, Ng KY, Zhou L, Tong M, Wong TL, Yu H, Lo CM, Man K, Guan XY, Lee TK and Ma S. Deficiency in embryonic stem cell marker REX1 activates MKK6-dependent p38 MAPK signaling to drive hepatocarcinogenesis. (2019) Hepatology. Pubmed Hepatology
Zhang XQ, Yao C, Bian WH, Chen X, Xue JX, Zhu ZY, Ying Y, Xu YL and Wang C. Effects of Astragaloside IV on treatment of breast cancer cells execute possibly through regulation of Nrf2 via PI3K/AKT/mTOR signaling pathway. (2019) Food Sci Nutr. 7, 3403-3413 Pubmed Food Sci Nutr PMC Article
Yu H, Wu CL, Wang X, Ban Q, Quan C, Liu M, Dong H, Li J, Kim GY, Choi YH, Wang Z and Jin CY. SP600125 enhances C-2-induced cell death by the switch from autophagy to apoptosis in bladder cancer cells. (2019) J. Exp. Clin. Cancer Res.. 38, 448 Pubmed J. Exp. Clin. Cancer Res. PMC Article
Ruhee RT, Ma S and Suzuki K. Sulforaphane Protects Cells against Lipopolysaccharide-Stimulated Inflammation in Murine Macrophages. (2019) Antioxidants (Basel). 8, Pubmed Antioxidants (Basel)
Wang Y, Chen Q, Shi C, Jiao F and Gong Z. Mechanism of glycyrrhizin on ferroptosis during acute liver failure by inhibiting oxidative stress. (2019) Mol Med Rep. 20, 4081-4090 Pubmed Mol Med Rep PMC Article
Kim DH, Jang JH, Kwon OS, Cha HJ, Chun KS and Surh YJ. Nrf2-induced reductive stress favours self-renewal of breast cancer stem-like cells via the FoxO3a-Bmi-1 axis. (2019) Antioxid. Redox Signal.. Pubmed Antioxid. Redox Signal.
Geng X, Yang B, Li R, Teng T, Ladu MJ, Sun GY, Greenlief CM and Lee JC. Effects of Docosahexaenoic Acid and Its Peroxidation Product on Amyloid-β Peptide-Stimulated Microglia. (2019) Mol. Neurobiol.. Pubmed Mol. Neurobiol.
Guo M, Lu H, Qin J, Qu S, Wang W, Guo Y, Liao W, Song M, Chen J and Wang Y. Biochanin A Provides Neuroprotection Against Cerebral Ischemia/Reperfusion Injury by Nrf2-Mediated Inhibition of Oxidative Stress and Inflammation Signaling Pathway in Rats. (2019) Med. Sci. Monit.. 25, 8975-8983 Pubmed Med. Sci. Monit.
Wang T, Liu Q and Duan L. MBNL1 regulates resistance of HeLa cells to cisplatin via Nrf2. (2019) Biochem. Biophys. Res. Commun.. Pubmed Biochem. Biophys. Res. Commun.
Nadal E, Palmero R and Muñoz-Pinedo C. Mutations in the Antioxidant KEAP1/NRF2 Pathway Define an Aggressive Subset of NSCLC Resistant to Conventional Treatments. (2019) J Thorac Oncol. 14, 1881-1883 Pubmed J Thorac Oncol
Dai N, Huang SQ, Tang CL, Tan CF, Dai P, Zeng TT, Zhu ZW and Yang ZX. [Electroacupuncture improves locomotor function by regulating expression of inflammation and oxidative stress-related proteins in mice with spinal cord injury]. (2019) Zhen Ci Yan Jiu. 44, 781-6 Pubmed Zhen Ci Yan Jiu
Bai M, Pan CL, Jiang GX, Zhang YM and Zhang Z. Effects of butylphthalide on oxidative stress and inflammatory response in rats with myocardial infarction through Akt/Nrf2 signaling pathway. (2019) Eur Rev Med Pharmacol Sci. 23, 9642-9650 Pubmed Eur Rev Med Pharmacol Sci
Hua CC. Associations between the Nrf2/Keap1 pathway and mitochondrial functions in colorectal cancer are affected by metastasis. (2019) Cancer Biomark. Pubmed Cancer Biomark
Uddin MS, Mamun AA, Jakaria M, Thangapandiyan S, Ahmad J, Rahman MA, Mathew B, Abdel-Daim MM and Aleya L. Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders. (2019) Sci. Total Environ.. 135624 Pubmed Sci. Total Environ.
Takahashi M, Fujii G, Hamoya T, Kurokawa Y, Matsuzawa Y, Miki K, Komiya M, Narita T and Mutoh M. Activation of NF-E2 p45-related factor-2 transcription and inhibition of intestinal tumor development by AHCC, a standardized extract of cultured mycelia. (2019) J Clin Biochem Nutr. 65, 203-208 Pubmed J Clin Biochem Nutr PMC Article
Silva MM, Rocha CRR, Kinker GS, Pelegrini AL and Menck CFM. The balance between NRF2/GSH antioxidant mediated pathway and DNA repair modulates cisplatin resistance in lung cancer cells. (2019) Sci Rep. 9, 17639 Pubmed Sci Rep
Zimta AA, Schitcu V, Gurzau E, Stavaru C, Manda G, Szedlacsek S and Berindan-Neagoe I. Biological and molecular modifications induced by cadmium and arsenic during breast and prostate cancer development. (2019) Environ. Res.. 178, 108700 Pubmed Environ. Res.
Gagliardi M, Cotella D, Santoro C, Corà D, Barlev NA, Piacentini M and Corazzari M. Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis. (2019) Cell Death Dis. 10, 902 Pubmed Cell Death Dis PMC Article
Luo J, Long Y, Ren G, Zhang Y, Chen J, Huang R and Yang L. Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy. (2019) J Med Food. Pubmed J Med Food
Huang S, Wang H, Chen W, Zhan M, Xu S, Huang X, Lin R, Shen H and Wang J. Tamoxifen inhibits cell proliferation by impaired glucose metabolism in gallbladder cancer. (2019) J. Cell. Mol. Med.. Pubmed J. Cell. Mol. Med.
Iqubal A, Sharma S, Najmi AK, Syed MA, Ali J, Alam MM and Haque SE. Nerolidol ameliorates cyclophosphamide-induced oxidative stress, neuroinflammation and cognitive dysfunction: Plausible role of Nrf2 and NF- κB. (2019) Life Sci.. 236, 116867 Pubmed Life Sci.
Kushwaha PP, Gupta S, Singh AK, Prajapati KS, Shuaib M and Kumar S. MicroRNA Targeting Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Cancer. (2019) Antioxid. Redox Signal.. Pubmed Antioxid. Redox Signal.
Ho CJ and Gorski SM. Molecular Mechanisms Underlying Autophagy-Mediated Treatment Resistance in Cancer. (2019) Cancers (Basel). 11, Pubmed Cancers (Basel)
Zhou Y, Wang K, Zhou Y, Li T, Yang M, Wang R, Chen Y, Cao M and Hu R. HEATR1 deficiency promotes pancreatic cancer proliferation and gemcitabine resistance by up-regulating Nrf2 signaling. (2019) Redox Biol. 29, 101390 Pubmed Redox Biol
Badshah H, Ikram M, Ali W, Ahmad S, Hahm JR and Kim MO. Caffeine May Abrogate LPS-Induced Oxidative Stress and Neuroinflammation by Regulating Nrf2/TLR4 in Adult Mouse Brains. (2019) Biomolecules. 9, Pubmed Biomolecules
Lee SM, Kim NH, Lee S, Kim YN, Heo JD, Jeong EJ and Rho JR. Deacetylphylloketal, a New Phylloketal Derivative from a Marine Sponge, Genus , with Potent Anti-Inflammatory Activity in In Vitro Co-Culture Model of Intestine. (2019) Mar Drugs. 17, Pubmed Mar Drugs
Zhang Z, Li H, Liang Z, Li C, Yang Z, Li Y, Cao L, She Y, Wang W, Liu C and Chen L. Vaporized perfluorocarbon inhalation attenuates primary blast lung injury in canines by inhibiting mitogen-activated protein kinase/nuclear factor-κB activation and inducing nuclear factor, erythroid 2 like 2 pathway. (2019) Toxicol. Lett.. 319, 49-57 Pubmed Toxicol. Lett.
Robinson RM, Reyes L, Duncan RM, Bian H, Strobel ED, Hyman SL, Reitz AB and Dolloff NG. Tuning isoform selectivity and bortezomib sensitivity with a new class of alkenyl indene PDI inhibitor. (2019) Eur J Med Chem. 111906 Pubmed Eur J Med Chem
Bai T, Lei P, Zhou H, Liang R, Zhu R, Wang W, Zhou L and Sun Y. Sigma-1 receptor protects against ferroptosis in hepatocellular carcinoma cells. (2019) J. Cell. Mol. Med.. 23, 7349-7359 Pubmed J. Cell. Mol. Med. PMC Article
Liu X, Bai J, Jiang C, Song Z, Zhao Y, Nauwynck H and Jiang P. Therapeutic effect of Xanthohumol against highly pathogenic porcine reproductive and respiratory syndrome viruses. (2019) Vet. Microbiol.. 238, 108431 Pubmed Vet. Microbiol.
Carota G, Raffaele M, Sorrenti V, Salerno L, Pittalà V and Intagliata S. Ginseng and heme oxygenase-1: The link between an old herb and a new protective system. (2019) Fitoterapia. 139, 104370 Pubmed Fitoterapia
Dai P, Shen D, Shen J, Tang Q, Xi M, Li Y and Li C. The roles of Nrf2 and autophagy in modulating inflammation mediated by TLR4 - NFκB in A549 cell exposed to layer house particulate matter 2.5 (PM). (2019) Chemosphere. 235, 1134-1145 Pubmed Chemosphere
Lian W, Liu X and Chen W. TNFα Induces Multidrug Resistance-Associated Protein 4 Expression through p38-E2F1-Nrf2 Signaling in Obstructive Cholestasis. (2019) Yonsei Med. J.. 60, 1045-1053 Pubmed Yonsei Med. J. PMC Article
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