English: Graph of Nrf2 publications (pubmed se...

English: Graph of Nrf2 publications (pubmed search) by year (Photo credit: Wikipedia)

There are currently over 2300 articles (peer reviewed clinical reviews and studies) on Pubmed.gov on the topic of NRF2 Activation. There are a ton of companies claiming they have scientific studies showing that their products are NRF2 Activators. Go to Pubmed.gov and type in the name of their product. Pubmed is a website operated by the National Institute of Health (NIH).  PubMed comprises over 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. PubMed citations and abstracts include the fields of biomedicine and health, covering portions of the life sciences, behavioral sciences, chemical sciences, and bioengineering. PubMed also provides access to additional relevant web sites and links to the other NCBI molecular biology resources. Last 200 NRF-2 Studies published on Pubmed
Jiang M, Jin J, Ye X, Wang J, Shen H, Zhen J, Zhou Y, Hiroyuki C and Uberla K. Construction of Lycetin Nanocarriers and Its Effect on the Proliferation and Apoptosis of Hepatocellular Carcinoma Cells by Regulating Nuclear Factor E2 Related Factor/Antioxidant Response Element Pathway. (2021) J Nanosci Nanotechnol. 21, 1054-1060 Pubmed J Nanosci Nanotechnol
Lou JS, Zhao LP, Huang ZH, Chen XY, Xu JT, Tai WC, Tsim KWK, Chen YT and Xie T. Ginkgetin derived from Ginkgo biloba leaves enhances the therapeutic effect of cisplatin via ferroptosis-mediated disruption of the Nrf2/HO-1 axis in EGFR wild-type non-small-cell lung cancer. (2021) Phytomedicine. 80, 153370 Pubmed Phytomedicine
Paithankar JG, Saini S, Dwivedi S, Sharma A and Chowdhuri DK. Heavy metal associated health hazards: An interplay of oxidative stress and signal transduction. (2021) Chemosphere. 262, 128350 Pubmed Chemosphere
Jessen C, Kreß JKC, Baluapuri A, Hufnagel A, Schmitz W, Kneitz S, Roth S, Marquardt A, Appenzeller S, Ade CP, Glutsch V, Wobser M, Friedmann-Angeli JP, Mosteo L, Goding CR, Schilling B, Geissinger E, Wolf E and Meierjohann S. Correction: The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression. (2020) Oncogene. Pubmed Oncogene
Ribeiro Reily Rocha C, Reily Rocha A, Molina Silva M, Rodrigues Gomes L, Teatin Latancia M, Andrade Tomaz M, de Souza I, Karolynne Seregni Monteiro L and Frederico Martins Menck C. Revealing Temozolomide Resistance Mechanisms via Genome-Wide CRISPR Libraries. (2020) Cells. 9, Pubmed Cells
Payandeh Z, Pirpour Tazehkand A, Barati G, Pouremamali F, Kahroba H, Baradaran B and Samadi N. Role of Nrf2 and mitochondria in cancer stem cells; in carcinogenesis, tumor progression, and chemoresistance. (2020) Biochimie. 179, 32-45 Pubmed Biochimie
Zhang F, Liu Z, He X, Li Z, Shi B and Cai F. β-Sitosterol-loaded solid lipid nanoparticles ameliorate complete Freund's adjuvant-induced arthritis in rats: involvement of NF-кB and HO-1/Nrf-2 pathway. (2020) Drug Deliv. 27, 1329-1341 Pubmed Drug Deliv PMC Article
Acito M, Bartolini D, Ceccarini MR, Russo C, Vannini S, Dominici L, Codini M, Villarini M, Galli F, Beccari T and Moretti M. Imbalance in the antioxidant defence system and pro-genotoxic status induced by high glucose concentrations: In vitro testing in human liver cells. (2020) Toxicol In Vitro. 69, 105001 Pubmed Toxicol In Vitro
Scheifele C, Zhu Q, Ignatov A, Kalinski T and Nass N. Glyoxalase 1 expression analysis by immunohistochemistry in breast cancer. (2020) Pathol Res Pract. 216, 153257 Pubmed Pathol Res Pract
Albazal A, Delshad AA and Roghani M. Melatonin reverses cognitive deficits in streptozotocin-induced type 1 diabetes in the rat through attenuation of oxidative stress and inflammation. (2020) J Chem Neuroanat. 101902 Pubmed J Chem Neuroanat
Zhao D, Xue C, Li J, Feng K, Zeng P, Chen Y, Duan Y, Zhang S, Li X, Han J and Yang X. Adiponectin agonist ADP355 ameliorates doxorubicin-induced cardiotoxicity by decreasing cardiomyocyte apoptosis and oxidative stress. (2020) Biochem Biophys Res Commun. 533, 304-312 Pubmed Biochem Biophys Res Commun
Jiang Y, Zhang K, Yu Y, Wang Y, Lian N, Xie K and Yu Y. Molecular hydrogen alleviates brain injury and cognitive impairment in a chronic sequelae model of murine polymicrobial sepsis. (2020) Exp Brain Res. 238, 2897-2908 Pubmed Exp Brain Res
Guo H, Wang Y and Liu D. Silibinin ameliorats HO-induced cell apoptosis and oxidative stress response by activating Nrf2 signaling in trophoblast cells. (2020) Acta Histochem. 122, 151620 Pubmed Acta Histochem
Wu WL and Papagiannakopoulos T. The Center Cannot Hold: NRF2 Battles Ferroptosis in the 3rd Dimension. (2020) Mol Cell. 80, 760-761 Pubmed Mol Cell
Song CH, Kim N, Hee Nam R, In Choi S, Hee Son J, Eun Yu J, Shin E, Lee HN, Kim DH and Surh YJ. 17β-Estradiol strongly inhibits azoxymethane/dextran sulfate sodium-induced colorectal cancer development in Nrf2 knockout male mice. (2020) Biochem Pharmacol. 182, 114279 Pubmed Biochem Pharmacol
Ryu D, Lee JH and Kwak MK. NRF2 level is negatively correlated with TGF-β1-induced lung cancer motility and migration via NOX4-ROS signaling. (2020) Arch Pharm Res. 43, 1297-1310 Pubmed Arch Pharm Res
Barakat LAA, Barakat N, Zakaria MM and Khirallah SM. Protective role of zinc oxide nanoparticles in kidney injury induced by cisplatin in rats. (2020) Life Sci. 262, 118503 Pubmed Life Sci
Takahashi N, Cho P, Selfors LM, Kuiken HJ, Kaul R, Fujiwara T, Harris IS, Zhang T, Gygi SP and Brugge JS. 3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis. (2020) Mol Cell. 80, 828-844.e6 Pubmed Mol Cell
Yardim A, Kandemir FM, Ozdemir S, Kucukler S, Comakli S, Gur C and Celik H. Quercetin provides protection against the peripheral nerve damage caused by vincristine in rats by suppressing caspase 3, NF-κB, ATF-6 pathways and activating Nrf2, Akt pathways. (2020) Neurotoxicology. 81, 137-146 Pubmed Neurotoxicology
Zhang S, Niu Y, Yang Z, Zhang Y, Guo Q, Yang Y, Zhou X, Ding Y and Liu C. Biochanin A alleviates gingival inflammation and alveolar bone loss in rats with experimental periodontitis. (2020) Exp Ther Med. 20, 251 Pubmed Exp Ther Med PMC Article
Liu RM, Xu P, Chen Q, Feng SL and Xie Y. A multiple-targets alkaloid nuciferine overcomes paclitaxel-induced drug resistance in vitro and in vivo. (2020) Phytomedicine. 79, 153342 Pubmed Phytomedicine
Singh B, Patwardhan RS, Jayakumar S, Sharma D and Sandur SK. Oxidative stress associated metabolic adaptations regulate radioresistance in human lung cancer cells. (2020) J Photochem Photobiol B. 213, 112080 Pubmed J Photochem Photobiol B
Wang W, Zhang S, Yang F, Xie J, Chen J and Li Z. Diosmetin alleviates acute kidney injury by promoting the TUG1/Nrf2/HO-1 pathway in sepsis rats. (2020) Int Immunopharmacol. 88, 106965 Pubmed Int Immunopharmacol
Logie E and Vanden Berghe W. Tackling Chronic Inflammation with Withanolide Phytochemicals-A Withaferin a Perspective. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel) PMC Article
De Cicco P, Maisto M, Tenore GC and Ianaro A. Olive Leaf Extract, from L., Reduces Palmitate-Induced Inflammation via Regulation of Murine Macrophages Polarization. (2020) Nutrients. 12, Pubmed Nutrients
Hahm ER, Kim SH, Singh KB and Singh SV. RNA-seq reveals novel cancer-selective and disease subtype-independent mechanistic targets of withaferin A in human breast cancer cells. (2020) Mol Carcinog. Pubmed Mol Carcinog
Friedmann Angeli JP and Meierjohann S. NRF2 dependent stress defence in tumor antioxidant control and immune evasion. (2020) Pigment Cell Melanoma Res. Pubmed Pigment Cell Melanoma Res
Kaji H, Matsui-Yuasa I, Matsumoto K, Omura A, Kiyomoto K and Kojima-Yuasa A. Sesaminol prevents Parkinson's disease by activating the Nrf2-ARE signaling pathway. (2020) Heliyon. 6, e05342 Pubmed Heliyon PMC Article
Ali A, Shah SA, Zaman N, Uddin MN, Khan W, Ali A, Riaz M and Kamil A. Vitamin D exerts neuroprotection via SIRT1/nrf-2/ NF-kB signaling pathways against D-galactose-induced memory impairment in adult mice. (2020) Neurochem Int. 142, 104893 Pubmed Neurochem Int
Jiang T, Zhou J, Liu W, Tao W, He J, Jin W, Guo H, Yang N and Li Y. The anti-inflammatory potential of protein-bound anthocyanin compounds from purple sweet potato in LPS-induced RAW264.7 macrophages. (2020) Food Res Int. 137, 109647 Pubmed Food Res Int
Clerici S and Boletta A. Role of the KEAP1-NRF2 Axis in Renal Cell Carcinoma. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel) PMC Article
Liang J, Liu L, Kang X, Hu F and Mao L. Mechanism underlying the effect of SO2-induced oxidation on human skin keratinocytes. (2020) Medicine (Baltimore). 99, e23152 Pubmed Medicine (Baltimore)
Kim MW, Kang JH, Jung HJ, Park SY, Phan THL, Namgung H, Seo SY, Yoon YS and Oh SH. Allyl Isothiocyanate Protects Acetaminophen-Induced Liver Injury via NRF2 Activation by Decreasing Spontaneous Degradation in Hepatocyte. (2020) Nutrients. 12, Pubmed Nutrients PMC Article
Saha S, Buttari B, Panieri E, Profumo E and Saso L. An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation. (2020) Molecules. 25, Pubmed Molecules PMC Article
Wang X, Saud SM, Zhang X, Li W and Hua B. Corrigendum to: "Protective effect of Shaoyao decoction against colorectal cancer via the Keap1-Nrf2-ARE signaling pathway", [J. Ethnopharmacol. 241 (2019) 111981]. (2020) J Ethnopharmacol. 113532 Pubmed J Ethnopharmacol
Abdelzaher WY, Ahmed SM, Welson NN, Marraiki N, Batiha GE and Kamel MY. Vinpocetine ameliorates L-arginine induced acute pancreatitis via Sirt1/Nrf2/TNF pathway and inhibition of oxidative stress, inflammation, and apoptosis. (2020) Biomed Pharmacother. 133, 110976 Pubmed Biomed Pharmacother
Thanas C, Ziros PG, Chartoumpekis DV, Renaud CO and Sykiotis GP. The Keap1/Nrf2 Signaling Pathway in the Thyroid-2020 Update. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel) PMC Article
Wu YX, Zeng S, Wan BB, Wang YY, Sun HX, Liu G, Gao ZQ, Chen D, Chen YQ, Lu MD and Pang QF. Sophoricoside attenuates lipopolysaccharide-induced acute lung injury by activating the AMPK/Nrf2 signaling axis. (2020) Int Immunopharmacol. 107187 Pubmed Int Immunopharmacol
Larrick J, Larrick JW and Mendelsohn AR. SUMO wrestles with mitophagy to extend lifespan. (2020) Rejuvenation Res. Pubmed Rejuvenation Res
Ma Y, Pan C, Tang X, Zhang M, Shi H, Wang T and Zhang Y. MicroRNA-200a represses myocardial infarction-related cell death and inflammation by targeting the Keap1/Nrf2 and β-catenin pathways. (2020) Hellenic J Cardiol. Pubmed Hellenic J Cardiol
Azouz AA, Abdel-Nassir Abdel-Razek E and Abo-Youssef AM. Amlodipine alleviates cisplatin-induced nephrotoxicity in rats through gamma-glutamyl transpeptidase (GGT) enzyme inhibition, associated with regulation of Nrf2/HO-1, MAPK/NF-κB, and Bax/Bcl-2 signaling. (2020) Saudi Pharm J. 28, 1317-1325 Pubmed Saudi Pharm J PMC Article
Qureshi MA, Khan S, Tauheed MS, Syed SA, Ujjan ID, Lail A and Sharafat S. Pan-Cancer Multiomics Analysis of TC2N Gene Suggests its Important Role(s) in Tumourigenesis of Many Cancers. (2020) Asian Pac J Cancer Prev. 21, 3199-3209 Pubmed Asian Pac J Cancer Prev
Yardım A, Kandemir FM, Çomaklı S, Özdemir S, Caglayan C, Kucukler S and Çelik H. Protective Effects of Curcumin Against Paclitaxel-Induced Spinal Cord and Sciatic Nerve Injuries in Rats. (2020) Neurochem Res. Pubmed Neurochem Res
Jaganjac M, Milkovic L, Sunjic SB and Zarkovic N. The NRF2, Thioredoxin, and Glutathione System in Tumorigenesis and Anticancer Therapies. (2020) Antioxidants (Basel). 9, Pubmed Antioxidants (Basel) PMC Article
Gureev AP, Sadovnikova IS, Starkov NN, Starkov AA and Popov VN. p62-Nrf2-p62 Mitophagy Regulatory Loop as a Target for Preventive Therapy of Neurodegenerative Diseases. (2020) Brain Sci. 10, Pubmed Brain Sci PMC Article
Zhou S, Guo J, Zhao L, Liao Y, Zhou Q, Cui Y, Hu W, Chen J, Ren X, Wei Q, Jiang S, Zheng Y, Li L, Wilcox CS, Persson PB, Patzak A, Tian J and Yin Lai E. ADAMTS13 inhibits oxidative stress and ameliorates progressive chronic kidney disease following ischaemia/reperfusion injury. (2020) Acta Physiol (Oxf). e13586 Pubmed Acta Physiol (Oxf)
Meng XW, He CX, Chen X, Yang XS and Liu C. The extract of Gnaphalium affine D. Don protects against HO-induced apoptosis by targeting PI3K/AKT/GSK-3β signaling pathway in cardiomyocytes. (2020) J Ethnopharmacol. 113579 Pubmed J Ethnopharmacol
Yang Y, Zheng J, Wang M, Zhang J, Tian T, Wang Z, Yuan S, Liu L, Zhu P, Gu F, Fu S, Shan Y, Pan Z and Zhou W. NQO1 promotes an aggressive phenotype in hepatocellular carcinoma via amplifying ERK-NRF2 signaling. (2020) Cancer Sci. Pubmed Cancer Sci
Kong Q, Deng H, Li C, Wang X, Shimoda Y, Tao S, Kato K, Zhang J, Yamanaka K and An Y. Sustained high expression of NRF2 and its target genes induces dysregulation of cellular proliferation and apoptosis is associated with arsenite-induced malignant transformation of human bronchial epithelial cells. (2020) Sci Total Environ. 143840 Pubmed Sci Total Environ
Bailly C. Atractylenolides, essential components of Atractylodes-based traditional herbal medicines: antioxidant, anti-inflammatory and anticancer properties. (2020) Eur J Pharmacol. 173735 Pubmed Eur J Pharmacol
Fouzder C, Mukhuty A and Kundu R. Kaempferol inhibits Nrf2 signalling pathway via downregulation of Nrf2 mRNA and induces apoptosis in NSCLC cells. (2020) Arch Biochem Biophys. 108700 Pubmed Arch Biochem Biophys
de Oliveira MR, de Souza ICC and Brasil FB. Mitochondrial Protection and Anti-inflammatory Effects Induced by Emodin in the Human Neuroblastoma SH-SY5Y Cells Exposed to Hydrogen Peroxide: Involvement of the AMPK/Nrf2 Signaling Pathway. (2020) Neurochem Res. Pubmed Neurochem Res
Zhang J, Wang J, Fang H, Yu H, Zhao Y, Shen J, Zhou C and Jin Y. Pterostilbene inhibits deoxynivalenol-induced oxidative stress and inflammatory response in bovine mammary epithelial cells. (2020) Toxicon. 189, 10-18 Pubmed Toxicon
Hu Z, Wang X, Li D, Cao L, Cui H and Xu G. UFBP1, a key component in ufmylation, enhances drug sensitivity by promoting proteasomal degradation of oxidative stress-response transcription factor Nrf2. (2020) Oncogene. Pubmed Oncogene
Merk R, Heßelbach K, Osipova A, Popadić D, Schmidt-Heck W, Kim GJ, Günther S, Piñeres AG, Merfort I and Humar M. Particulate Matter (PM) from Biomass Combustion Induces an Anti-Oxidative Response and Cancer Drug Resistance in Human Bronchial Epithelial BEAS-2B Cells. (2020) Int J Environ Res Public Health. 17, Pubmed Int J Environ Res Public Health PMC Article
Okazaki K, Anzawa H, Liu Z, Ota N, Kitamura H, Onodera Y, Alam MM, Matsumaru D, Suzuki T, Katsuoka F, Tadaka S, Motoike I, Watanabe M, Hayasaka K, Sakurada A, Okada Y, Yamamoto M, Suzuki T, Kinoshita K, Sekine H and Motohashi H. Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers. (2020) Nat Commun. 11, 5911 Pubmed Nat Commun PMC Article
Guo S, Li Y, Wei B, Liu W, Li R, Cheng W, Zhang X, He X, Li X and Duan C. Tim-3 deteriorates neuroinflammatory and neurocyte apoptosis after subarachnoid hemorrhage through the Nrf2/HMGB1 signaling pathway in rats. (2020) Aging (Albany NY). 12, 21161-21185 Pubmed Aging (Albany NY)
Tamatam CM, Reddy NM, Potteti HR, Ankireddy A, Noone PM, Yamamoto M, Kensler TW and Reddy SP. Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice. (2020) Sci Rep. 10, 19034 Pubmed Sci Rep PMC Article
Liu J, Cui JY, Lu YF, Corton JC and Klaassen CD. Sex-, age-, and race/ethnicity-dependent variations in drug-processing and NRF2-regulated genes in human livers. (2020) Drug Metab Dispos. Pubmed Drug Metab Dispos
Liao H, Ye J, Gao L and Liu Y. The main bioactive compounds of Scutellaria baicalensis Georgi. for alleviation of inflammatory cytokines: A comprehensive review. (2020) Biomed Pharmacother. 133, 110917 Pubmed Biomed Pharmacother
Calabrese EJ and Kozumbo WJ. The phytoprotective agent sulforaphane prevents inflammatory degenerative diseases and age-related pathologies via Nrf2-mediated hormesis. (2020) Pharmacol Res. 105283 Pubmed Pharmacol Res
Manga P and Choudhury N. The Unfolded Protein and Integrated Stress Response in Melanoma and Vitiligo. (2020) Pigment Cell Melanoma Res. Pubmed Pigment Cell Melanoma Res
Zhong S, Xue J, Cao JJ, Sun B, Sun QF, Bian LG, Hu LY and Pan SJ. The therapeutic value of XL388 in human glioma cells. (2020) Aging (Albany NY). 12, Pubmed Aging (Albany NY)
Inesta-Vaquera F, Navasumrit P, Henderson CJ, Frangova TG, Honda T, Dinkova-Kostova AT, Ruchirawat M and Wolf CR. Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity. (2020) Environ Pollut. 116053 Pubmed Environ Pollut
Li Z, Teng M, Wang Y, Feng Y, Xiao Z, Hu H, Wang Q, Lu Y, Li C, Zeng K and Yang B. Dihydroartemisinin administration improves the effectiveness of 5-aminolevulinic acid-mediated photodynamic therapy for the treatment of high-risk human papillomavirus infection. (2020) Photodiagnosis Photodyn Ther. 102078 Pubmed Photodiagnosis Photodyn Ther
Zamani E, Parviz M, Roghani M, Hosseini M, Mohseni-Moghaddam P and Nikbakhtzadeh M. Netrin-1 protects the SH-SY5Y cells against amyloid beta neurotoxicity through NF-κB/Nrf2 dependent mechanism. (2020) Mol Biol Rep. Pubmed Mol Biol Rep
Gupta N, Verma K, Nalla S, Kulshreshtha A, Lall R and Prasad S. Free Radicals as a Double-Edged Sword: The Cancer Preventive and Therapeutic Roles of Curcumin. (2020) Molecules. 25, Pubmed Molecules PMC Article
Horiuchi M, Taguchi K, Hirose W, Tsuchida K, Suzuki M, Taniyama Y, Kamei T and Yamamoto M. Cellular Nrf2 Levels Determine Cell Fate during Chemical Carcinogenesis in Esophageal Epithelium. (2020) Mol Cell Biol. Pubmed Mol Cell Biol
Liang Y, Zheng B, Li J, Shi J, Chu L, Han X, Chu X, Zhang X and Zhang J. Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis. (2020) Biomed Pharmacother. 131, 110713 Pubmed Biomed Pharmacother
Wu Q, Ma Y, Liu Y, Wang N, Zhao X and Wen D. CB2R agonist JWH-133 attenuates chronic inflammation by restraining M1 macrophage polarization via Nrf2/HO-1 pathway in diet-induced obese mice. (2020) Life Sci. 260, 118424 Pubmed Life Sci
Sim H, Choo S, Kim J, Baek MC and Bae JS. Fisetin Suppresses Pulmonary Inflammatory Responses Through Heme Oxygenase-1 Mediated Downregulation of Inducible Nitric Oxide Synthase. (2020) J Med Food. 23, 1163-1168 Pubmed J Med Food
Zhang T, Shi L, Li Y, Mu W, Zhang H, Li Y, Wang X, Zhao W, Qi Y and Liu L. Polysaccharides extracted from Rheum tanguticum ameliorate radiation-induced enteritis via activation of Nrf2/HO-1. (2020) J Radiat Res. Pubmed J Radiat Res
Yang L, Yuan Z, Zhang Y, Cui Z, Li Y, Hou J, Liu X, Liu Z, Shi R, Tian Q, Wang J and Wang L. MiniPDX-guided postoperative anticancer treatment can effectively prolong the survival of patients with hepatocellular carcinoma. (2020) Cancer Chemother Pharmacol. Pubmed Cancer Chemother Pharmacol
Baird L and Yamamoto M. NRF2-dependent bioactivation of mitomycin C as a novel strategy to target KEAP1-NRF2 pathway activation in human cancer. (2020) Mol Cell Biol. Pubmed Mol Cell Biol
Jamali N, Zal F, Mostafavi-Pour Z, Samare-Najaf M, Poordast T and Dehghanian A. Ameliorative Effects of Quercetin and Metformin and Their Combination Against Experimental Endometriosis in Rats. (2020) Reprod Sci. Pubmed Reprod Sci
Shaw P, Sen A, Mondal P, Dey Bhowmik A, Rath J and Chattopadhyay A. Shinorine ameliorates chromium induced toxicity in zebrafish hepatocytes through the facultative activation of Nrf2-Keap1-ARE pathway. (2020) Aquat Toxicol. 228, 105622 Pubmed Aquat Toxicol
Bose C, Alves I, Singh P, Palade PT, Carvalho E, Børsheim E, Jun SR, Cheema A, Boerma M, Awasthi S and Singh SP. Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling. (2020) Aging Cell. 19, e13261 Pubmed Aging Cell PMC Article
Wang Y, Cui X, Lin Q, Cai J, Tang L and Liang Y. Active Peptide KF-8 from Rice Bran Attenuates Oxidative Stress in a Mouse Model of Aging Induced by d-Galactose. (2020) J Agric Food Chem. 68, 12271-12283 Pubmed J Agric Food Chem
Elsherbiny NM, Eisa NH, El-Sherbiny M and Said E. Chemo-preventive effect of crocin against experimentally-induced hepatocarcinogenesis via regulation of apoptotic and Nrf2 signaling pathways. (2020) Environ Toxicol Pharmacol. 80, 103494 Pubmed Environ Toxicol Pharmacol
Li M, Liu P, Xue Y, Liang Y, Shi J, Han X, Zhang J, Chu X and Chu L. Tannic acid attenuates hepatic oxidative stress, apoptosis and inflammation by activating the Keap1‑Nrf2/ARE signaling pathway in arsenic trioxide‑toxicated rats. (2020) Oncol Rep. 44, 2306-2316 Pubmed Oncol Rep
Gu X, Shi Y, Chen X, Sun Z, Luo W, Hu X, Jin G, You S, Qian Y, Wu W, Liang G, Wu G, Chen Z and Chen X. Isoliquiritigenin attenuates diabetic cardiomyopathy via inhibition of hyperglycemia-induced inflammatory response and oxidative stress. (2020) Phytomedicine. 78, 153319 Pubmed Phytomedicine
Mehranfard N, Yazdi A, Rafiei A, Shakerin Z and Ghasemi M. Honey protects against chronic unpredictable mild stress induced- intestinal barrier disintegration and hepatic inflammation. (2020) Mol Biol Rep. 47, 8475-8484 Pubmed Mol Biol Rep
Elgendy SM, Alyammahi SK, Alhamad DW, Abdin SM and Omar HA. Ferroptosis: An emerging approach for targeting cancer stem cells and drug resistance. (2020) Crit Rev Oncol Hematol. 155, 103095 Pubmed Crit Rev Oncol Hematol
Khaled S, Makled MN and Nader MA. Tiron protects against nicotine-induced lung and liver injury through antioxidant and anti-inflammatory actions in rats in vivo. (2020) Life Sci. 260, 118426 Pubmed Life Sci
Zhu Y, Yang Q, Liu H, Song Z and Chen W. Phytochemical compounds targeting on Nrf2 for chemoprevention in colorectal cancer. (2020) Eur J Pharmacol. 887, 173588 Pubmed Eur J Pharmacol
DeBlasi JM and DeNicola GM. Dissecting the Crosstalk between NRF2 Signaling and Metabolic Processes in Cancer. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel) PMC Article
Licznerska B, Szaefer H and Krajka-Kuźniak V. R-sulforaphane modulates the expression profile of AhR, ERα, Nrf2, NQO1, and GSTP in human breast cell lines. (2020) Mol Cell Biochem. Pubmed Mol Cell Biochem
Yardım A, Kucukler S, Özdemir S, Çomaklı S, Caglayan C, Kandemir FM and Çelik H. Silymarin alleviates docetaxel-induced central and peripheral neurotoxicity by reducing oxidative stress, inflammation and apoptosis in rats. (2020) Gene. 145239 Pubmed Gene
Deville SS, Luft S, Kaufmann M and Cordes N. Keap1 inhibition sensitizes head and neck squamous cell carcinoma cells to ionizing radiation via impaired non-homologous end joining and induced autophagy. (2020) Cell Death Dis. 11, 887 Pubmed Cell Death Dis PMC Article
Liu Z and Sun X. A Critical Review of the Abilities, Determinants, and Possible Molecular Mechanisms of Seaweed Polysaccharides Antioxidants. (2020) Int J Mol Sci. 21, Pubmed Int J Mol Sci PMC Article
Mohamed ME, Abduldaium YS and Younis NS. Ameliorative Effect of Linalool in Cisplatin-Induced Nephrotoxicity: The Role of HMGB1/TLR4/NF-κB and Nrf2/HO1 Pathways. (2020) Biomolecules. 10, Pubmed Biomolecules PMC Article
Sampath C, Okoro EU, Gipson MJ, Chukkapalli SS, Farmer-Dixon CM and Gangula PR. Porphyromonas gingivalis infection alters Nrf2-Phase II enzymes and nitric oxide in primary human aortic endothelial cells. (2020) J Periodontol. Pubmed J Periodontol
Waz S, Heeba GH, Hassanin SO and Abdel-Latif RG. Nephroprotective effect of exogenous hydrogen sulfide donor against cyclophosphamide-induced toxicity is mediated by Nrf2/HO-1/NF-κB signaling pathway. (2020) Life Sci. 118630 Pubmed Life Sci
Wan Z, Li H, Wu X, Zhao H, Wang R, Li M, Liu J, Liu Q, Wang R and Li X. Hepatoprotective effect of gentiopicroside in combination with leflunomide and/or methotrexate in arthritic rats. (2020) Life Sci. 118689 Pubmed Life Sci
Li YJ, Shimizu T, Shinkai Y, Ihara T, Sugamata M, Kato K, Kobayashi M, Hirata Y, Inagaki H, Uzuki M, Akimoto T, Umezawa M, Takeda K, Azuma A, Yamamoto M and Kawada T. Nrf2 Lowers the Risk of Lung Injury via Modulating the Airway Innate Immune Response Induced by Diesel Exhaust in Mice. (2020) Biomedicines. 8, Pubmed Biomedicines PMC Article
Qiu L, Ma Z, Li X, Deng Y, Duan G, Zhao L, Xu X, Xiao L, Liu H, Zhu Z and Chen H. DJ-1 is involved in the multidrug resistance of SGC7901 gastric cancer cells through PTEN/PI3K/Akt/Nrf2 pathway. (2020) Acta Biochim Biophys Sin (Shanghai). Pubmed Acta Biochim Biophys Sin (Shanghai)
Abouzed TK, Beltagy ER, Kahilo KA and Ibrahim WM. Molecular changes associated with the anticancer effect of sulforaphane against Ehrlich solid tumour in mice. (2020) J Biochem Mol Toxicol. e22655 Pubmed J Biochem Mol Toxicol
Singh A, Daemen A, Nickles D, Jeon SM, Foreman O, Sudini K, Gnad F, Lajoie S, Gour N, Mitzner W, Chatterjee S, Choi EJ, Ravishankar B, Rappaport A, Patil NS, McCleland M, Johnson L, Acquaah-Mensah GK, Gabrielson E, Biswal S and Hatzivassiliou G. NRF2 activation promotes aggressive lung cancer and associates with poor clinical outcomes. (2020) Clin Cancer Res. Pubmed Clin Cancer Res
Abusarah J, Cui Y, El-Hachem N, El-Kadiry AE, Hammond-Martel I, Wurtele H, Beaudry A, Raynal NJ, Robert F, Pelletier J, Jankovic M, Mercier F, Kamyabiazar S, Annabi B and Rafei M. TACIMA-218: A NOVEL PRO-OXIDANT AGENT EXHIBITING SELECTIVE ANTI-TUMORAL ACTIVITY. (2020) Mol Cancer Ther. Pubmed Mol Cancer Ther
Orozco-Morales M, Hernández-Pedro NY, Barrios-Bernal P, Arrieta O, Ruiz-Godoy LM, Aschner M, Santamaría A and Colín-González AL. S-allylcysteine induces cytotoxic effects in two human lung cancer cell lines via induction of oxidative damage, downregulation of Nrf2 and NF-κB, and apoptosis. (2020) Anticancer Drugs. Pubmed Anticancer Drugs
Di Sotto A, Mancinelli R, Gullì M, Eufemi M, Mammola CL, Mazzanti G and Di Giacomo S. Chemopreventive Potential of Caryophyllane Sesquiterpenes: An Overview of Preliminary Evidence. (2020) Cancers (Basel). 12, Pubmed Cancers (Basel) PMC Article
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