Reversal of persistent fibrosis in aging by targeting nox4-Nrf2 redox imbalance – Sciencemag.org

A brand new article in Sciencemag.org presents a study demonstrating how pathological fibrosis increases with age, but how NRF2 activation in mice was able to reverse the damage and repair lung capacity and fibrosis (scar tissue) resolution. This is a promising study because the current treatments of pathological  and cystic fibrosis are costly and very… Continue reading Reversal of persistent fibrosis in aging by targeting nox4-Nrf2 redox imbalance – Sciencemag.org

Inflammation: A Major Contributor to Disease and Aging. Can Nrf2 Help Reduce It?

As the boomer generation ages it is probable that there will be more posts such as the one I saw this week from a friend on Facebook. Their plea was for suggestions and recommendations for a good solution to help alleviate the pain they were experiencing from inflammation. Externally, inflammation can be recognized by redness,… Continue reading Inflammation: A Major Contributor to Disease and Aging. Can Nrf2 Help Reduce It?

A New Nrf2 and Diabetes Study Underway

The American Diabetes Journal has details on an interesting NRF2 study currently in progress. Diabetes is a huge concern to many individuals and families. According to statistics published by the American Diabetes Association  more than 25.8 million children and adults in the United States in 2010 have diabetes. That accounts for 8.3% of the population.… Continue reading A New Nrf2 and Diabetes Study Underway

New Grant Issued for Nrf2 and Epilepsy Prevention Study

Professor Matthew Walker and his fellow researchers, at University College London (UCL), have some promising early evidence in epilepsy and NRF2 research. Their research targets two approaches, 1) By targeting anti-oxidant treatments to inhibit the enzymes that produce ROS (Approach A: An attacking approach) and 2) by increasing the ability of neurons to break ROS down… Continue reading New Grant Issued for Nrf2 and Epilepsy Prevention Study

Fibromyalgia, Oxidative Stress and Nrf2 – Any Hope?

Before jumping into the impact of Nrf2 activation on Fibromyalgia and it potential benefits, let’s review a few common facts about the illness. What is Fibromyalgia? Fibromyalgia is a relatively common condition in which an individual experiences pain and discomfort throughout the body. Side effects of this pain are anxiety, lack of sleep, headaches, fatigue… Continue reading Fibromyalgia, Oxidative Stress and Nrf2 – Any Hope?